4.5 Review

The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens

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The Tumor Suppressor, p53 Regulates the γA-Crystallin Gene During Mouse Lens Development

X. -H. Hu et al.

CURRENT MOLECULAR MEDICINE (2014)

Article Developmental Biology

The cellular and molecular mechanisms of vertebrate lens development

Ales Cvekl et al.

DEVELOPMENT (2014)

Article Anatomy & Morphology

AP-2α is Required After Lens Vesicle Formation to Maintain Lens Integrity

Christine L. Kerr et al.

DEVELOPMENTAL DYNAMICS (2014)

Article Ophthalmology

Mutations in the ABCA3 Gene Are Associated With Cataract-Microcornea Syndrome

Peng Chen et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

Article Cell Biology

The roles of aV integrins in lens EMT and posterior capsular opacification

Fahmy A. Mamuya et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2014)

Article Public, Environmental & Occupational Health

Visual Axis Opacification in Children Following Paediatric Cataract Surgery

Ujjowala Devi Shrestha et al.

JOURNAL OF NEPAL MEDICAL ASSOCIATION (2014)

Article Multidisciplinary Sciences

Sumoylation differentially regulates Sp1 to control cell differentiation

Lili Gong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Biochemistry & Molecular Biology

Properties of membranes derived from the total lipids extracted from the human lens cortex and nucleus

Laxman Mainali et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)

Article Medicine, Research & Experimental

p53 Directly Regulates αA- and βA3/A1-Crystallin Genes to Modulate Lens Differentiation

W. -K. Ji et al.

CURRENT MOLECULAR MEDICINE (2013)

Article Cell Biology

Neuropeptides: Developmental Signals in Placode Progenitor Formation

Laura Lleras-Forero et al.

DEVELOPMENTAL CELL (2013)

Article Ophthalmology

Residual lens cortex material: Potential risk factor for endophthalmitis after phacoemulsification cataract surgery

Bingsheng Lou et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2013)

Editorial Material Biology

Chaperones: needed for both the good times and the bad times

Roy A. Quinlan et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2013)

Review Biochemistry & Molecular Biology

Lens and retina regeneration: new perspectives from model organisms

Karla Barbosa-Sabanero et al.

BIOCHEMICAL JOURNAL (2012)

Article Medicine, Research & Experimental

The Tumor Suppressor p53 Regulates c-Maf and Prox-1 to Control Lens Differentiation

F. -Y. Liu et al.

CURRENT MOLECULAR MEDICINE (2012)

Article Biophysics

Phases and domains in sphingomyelin-cholesterol membranes: structure and properties using EPR spin-labeling methods

Laxman Mainali et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2012)

Article Biochemistry & Molecular Biology

The small heat shock proteins family: The long forgotten chaperones

C. Garrido et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)

Article Ophthalmology

Modified technique for removal of Soemmerring ring and in-the-bag secondary intraocular lens placement in aphakic eyes

Dilraj S. Grewal et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2012)

Article Cell Biology

A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells

Miguel Jarrin et al.

MOLECULAR BIOLOGY OF THE CELL (2012)

Article Ophthalmology

Age-Related Cataract Is Associated with Type 2 Diabetes and Statin Use

Carolyn M. Machan et al.

OPTOMETRY AND VISION SCIENCE (2012)

Article Ophthalmology

Enhancement of Ubiquitin Conjugation Activity Reduces Intracellular Aggregation of V76D Mutant γD-Crystallin

Zhenzhen Liu et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)

Article Ophthalmology

MMP2 Activity is Critical for TGFβ2-Induced Matrix Contraction-Implications for Fibrosis

Julie A. Eldred et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)

Article Genetics & Heredity

Mutations in FYCO1 Cause Autosomal-Recessive Congenital Cataracts

Jianjun Chen et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Article Cell & Tissue Engineering

Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice

Katrin Arnold et al.

CELL STEM CELL (2011)

Article Biochemistry & Molecular Biology

Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens

Gregory J. Zablocki et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2011)

Article Ophthalmology

Secondary intraocular lens implantation after pediatric aphakia

Bharti R. Nihalani et al.

JOURNAL OF AAPOS (2011)

Review Biology

The lens as a model for fibrotic disease

J. A. Eldred et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)

Review Biology

Homeostasis in the vertebrate lens: mechanisms of solute exchange

Ralf Dahm et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)

Review Biology

Vitreoretinal influences on lens function and cataract

David C. Beebe et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)

Review Biology

The lens: a classical model of embryonic induction providing new insights into cell determination in early development

Lena Gunhaga

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)

Editorial Material Multidisciplinary Sciences

Blind attraction: The mechanism of an inherited congenital cataract

Neer Asherie

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia

Bharesh K. Chauhan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Neurosciences

The emerging role of forces in axonal elongation

Daniel M. Suter et al.

PROGRESS IN NEUROBIOLOGY (2011)

Article Multidisciplinary Sciences

Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma

Salil A. Lachke et al.

SCIENCE (2011)

Article Ophthalmology

Imaging of Forward Light-Scatter by Opacified Posterior Capsules Isolated from Pseudophakic Donor Eyes

Maartje C. J. van Bree et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

Article Ophthalmology

Role of anterior capsule polishing in residual lens epithelial cell proliferation

Xialin Liu et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2010)

Review Biochemistry & Molecular Biology

Lipids and the ocular lens

Douglas Borchman et al.

JOURNAL OF LIPID RESEARCH (2010)

Article Biochemistry & Molecular Biology

Partially Folded Aggregation Intermediates of Human yD-, yC-, and yS-Crystallin Are Recognized and Bound by Human αB-Crystallin Chaperone

Ligia Acosta-Sampson et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Review Physiology

Lens Gap Junctions in Growth, Differentiation, and Homeostasis

Richard T. Mathias et al.

PHYSIOLOGICAL REVIEWS (2010)

Article Multidisciplinary Sciences

Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development

Qin Yan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Ophthalmology

Molecular and cellular aspects of amphibian lens regeneration

Jonathan J. Henry et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2010)

Article Ophthalmology

Natural Course of Elschnig Pearl Formation and Disappearance

Oliver Findl et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)

Article Ophthalmology

The ultrastructure of Elschnig's pearls in a pseudophakic eye

Örn Sveinsson

ACTA OPHTHALMOLOGICA (2009)

Article Ophthalmology

Posterior Capsular Opacification A Problem Reduced but Not Yet Eradicated

Niranjan Awasthi et al.

ARCHIVES OF OPHTHALMOLOGY (2009)

Review Developmental Biology

Pax6 is essential for lens fiber cell differentiation

Ohad Shaham et al.

DEVELOPMENT (2009)

Review Ophthalmology

The lens capsule

Brian P. Danysh et al.

EXPERIMENTAL EYE RESEARCH (2009)

Review Medicine, Research & Experimental

Functions of the intermediate filament cytoskeleton in the eye lens

Shuhua Song et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Developmental Biology

Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells

Hsin-Yi Ho et al.

MECHANISMS OF DEVELOPMENT (2009)

Review Cell Biology

Retina and lens regeneration in anuran amphibians

Sergio Filoni

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)

Article Ophthalmology

TGFβ/Smad4-Dependent and -Independent Regulation of Human Lens Epithelial Cells

Lucy Jean Dawes et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)

Article Ophthalmology

Age-Related Changes in the Spatial Distribution of Human Lens α-Crystallin Products by MALDI Imaging Mass Spectrometry

Angus C. Grey et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)

Article Genetics & Heredity

Mutation of solute carrier SLC16A12 associates with a syndrome combining juvenile cataract with microcornea and renal glucosuria

Barbara Kloeckener-Gruissem et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2008)

Article Biochemistry & Molecular Biology

Glycation by ascorbic acid oxidation products leads to the aggregation of lens proteins

Mikhail Linetsky et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2008)

Article Ophthalmology

Expression and localisation of apical junctional complex proteins in lens epithelial cells

Yuki Sugiyama et al.

EXPERIMENTAL EYE RESEARCH (2008)

Review Ophthalmology

Eye manifestations of intrauterine infections and their impact on childhood blindness

Marilyn Baird Mets et al.

SURVEY OF OPHTHALMOLOGY (2008)

Article Ophthalmology

TGFβ-Induced contraction is not promoted by fibronectin-fibronectin receptor interaction, or αSMA expression

Lucy Jean Dawes et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)

Article Genetics & Heredity

Acute postnatal cataract formation in Smith-Lemh-Opitz syndrome

Halima Goodwin et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2008)

Review Immunology

Exploring the full spectrum of macrophage activation

David M. Mosser et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Review Ophthalmology

Genetic and epigenetic mechanisms of gene regulation during lens development

Ales Cvekl et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2007)

Article Biochemistry & Molecular Biology

The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression

Junling Jia et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Review Ophthalmology

The etiology of steroid cataract

Eric R. James

JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2007)

Article Biochemistry & Molecular Biology

Connexins in lens development and cataractogenesis

Xiaohua Gong et al.

JOURNAL OF MEMBRANE BIOLOGY (2007)

Article Genetics & Heredity

Autosomal recessive juvenile onset cataract associated with mutation in BFSP1

Ramya Devi Ramachandran et al.

HUMAN GENETICS (2007)

Article Ophthalmology

Bag-in-the-lens intraocular lens implantation in the pediatric eye

Marie-Jose Tassignon et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2007)

Review Ophthalmology

Crystallins in the eye: Function and pathology

Usha P. Andley

PROGRESS IN RETINAL AND EYE RESEARCH (2007)

Review Ophthalmology

Accommodating intraocular lenses: a critical review of present and future concepts

R. Menapace et al.

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2007)

Review Biochemistry & Molecular Biology

The lens circulation

Richard T. Mathias et al.

JOURNAL OF MEMBRANE BIOLOGY (2007)

Review Cell Biology

Extracellular matrix and integrin signaling in lens development and cataract

Elizabeth D. Wederell et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2006)

Review Cell Biology

Cell cycle regulation in the developing lens

Anne E. Griep

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Six3 activation of Pax6 expression is essential for mammalian lens induction and specification

Wei Liu et al.

EMBO JOURNAL (2006)

Article Ophthalmology

Short-term exposure to transforming growth factor β induces long-term fibrotic responses

I. Michael Wormstone et al.

EXPERIMENTAL EYE RESEARCH (2006)

Article Ophthalmology

Role of the unfolded protein response (UPR) in cataract formation

Kengo Ikesugi et al.

EXPERIMENTAL EYE RESEARCH (2006)

Article Ophthalmology

Ring-shaped caliper for better anterior capsulorhexis sizing and centration

Marie-Jose Tassignon et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2006)

Article Ophthalmology

A hierarchy of proliferative cells exists in mouse lens epithelium: Implications for lens maintenance

Mingyuan Zhou et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)

Article Medicine, Research & Experimental

Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat

M Mori et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Review Ophthalmology

Lens regeneration in mammals: A review

A Gwon

SURVEY OF OPHTHALMOLOGY (2006)

Review Cell Biology

Apoptosis in lens development and pathology

Qin Yan et al.

DIFFERENTIATION (2006)

Article Anatomy & Morphology

Lens and retina formation require expression of Pitx3 in Xenopus pre-lens Ectoderm

F Khosrowshahian et al.

DEVELOPMENTAL DYNAMICS (2005)

Article Biochemistry & Molecular Biology

α-Crystallin is a target gene of the farnesoid X-activated receptor in human livers

FY Lee et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Ophthalmology

Risk factors for idiopathic congenital/infantile cataract

B Haargaard et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)

Article Chemistry, Physical

Cholesterol ozonolysis: Kinetics, mechanism, and oligomer products

MA Dreyfus et al.

JOURNAL OF PHYSICAL CHEMISTRY A (2005)

Review Ophthalmology

Age-related nuclear cataract - oxidation is the key

RJW Truscott

EXPERIMENTAL EYE RESEARCH (2005)

Article Ophthalmology

Human lens phospholipid changes with age and cataract

L Huang et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)

Article Ophthalmology

Regulation of aquaporin water permeability in the lens

K Varadaraj et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)

Article Ophthalmology

Lens epithelial apoptosis and cell proliferation in human age-related cortical cataract

A Charakidas et al.

EUROPEAN JOURNAL OF OPHTHALMOLOGY (2005)

Article Ophthalmology

Effect of bag-in-the-lens implantation on posterior capsule opacification in human donor eyes and rabbit eyes

V De Groot et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2005)

Article Pharmacology & Pharmacy

Ozone exposure in vivo and formation of biologically active oxysterols in the lung

MK Pulfer et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Review Biochemistry & Molecular Biology

Sphingolipids in human lens membranes: an update on their composition and possible biological implications

MC Yappert et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2004)

Article Ophthalmology

Influence of optic edge design and anterior capsule polishing on posterior capsule fibrosis

S Sacu et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2004)

Article Anatomy & Morphology

Cell proliferation during the early stages of human eye development

D Bozanic et al.

ANATOMY AND EMBRYOLOGY (2004)

Article Ophthalmology

Ocular features of the congenital cataracts facial dysmorphism neuropathy syndrome

A Müllner-Eidenböck et al.

OPHTHALMOLOGY (2004)

Review Ophthalmology

Management of the anterior and posterior lens capsules and vitreous in pediatric cataract surgery

SQ Guo et al.

JOURNAL OF PEDIATRIC OPHTHALMOLOGY & STRABISMUS (2004)

Article Ophthalmology

Morphology of and visual performance with posterior subcapsular cataract

AR Vasavada et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2004)

Article Developmental Biology

A newt's eye view of lens regeneration

PA Tsonis et al.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2004)

Article Multidisciplinary Sciences

Evidence for ozone formation in human atherosclerotic arteries

P Wentworth et al.

SCIENCE (2003)

Article Ophthalmology

Epithelial transdifferentiation and cataract in the human lens

JM Marcantonio et al.

EXPERIMENTAL EYE RESEARCH (2003)

Article Multidisciplinary Sciences

Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens

S Nishimoto et al.

NATURE (2003)

Article Ophthalmology

Isolation and lipid characterization of cholesterol-enriched fractions in cortical and nuclear human lens fibers

M Rujoi et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)

Review Ophthalmology

Alpha-crystallin

J Horwitz

EXPERIMENTAL EYE RESEARCH (2003)

Article Biochemistry & Molecular Biology

Discordant expression of the sterol pathway in lens underlies simvastatin-induced cataracts in Chbb: Thom rats

RJ Cenedella et al.

JOURNAL OF LIPID RESEARCH (2003)

Article Ophthalmology

TGFβ-Smad signalling in postoperative human lens epithelial cells

S Saika et al.

BRITISH JOURNAL OF OPHTHALMOLOGY (2002)

Article Ophthalmology

Using BSS with viscoadaptives in the ultimate soft-shell technique

SA Arshinoff

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2002)

Article Ophthalmology

Bag-in-the-lens implantation of intraocular lenses

MJBR Tassignon et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2002)

Article Biochemistry & Molecular Biology

Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays

BK Chauhan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Unique and redundant connexin contributions to lens development

TW White

SCIENCE (2002)

Review Ophthalmology

Posterior capsule opacification: A cell biological perspective

IM Wormstone

EXPERIMENTAL EYE RESEARCH (2002)

Article Multidisciplinary Sciences

Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye

JM Collinson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Biochemistry & Molecular Biology

The ocular lens epithelium

SP Bhat

BIOSCIENCE REPORTS (2001)

Article Ophthalmology

Anterior capsule opacification

TA Macky et al.

INTERNATIONAL OPHTHALMOLOGY CLINICS (2001)

Article Biochemistry & Molecular Biology

Regulation of c-maf gene expression by Pax6 in cultured cells

M Sakai et al.

NUCLEIC ACIDS RESEARCH (2001)

Review Biochemistry & Molecular Biology

SPARC, a matricellular protein: at the crossroads of cell-matrix

RA Brekken et al.

MATRIX BIOLOGY (2000)

Article Ophthalmology

Lens epithelial cell proliferation in human posterior capsule opacification specimens

JM Rakic et al.

EXPERIMENTAL EYE RESEARCH (2000)

Article Ophthalmology

Effect of surgical technique on in vitro posterior capsule opacification

MG Davidson et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2000)

Article Biochemistry & Molecular Biology

Functional impairment of lens aquaporin in two families with dominantly inherited cataracts

P Francis et al.

HUMAN MOLECULAR GENETICS (2000)

Article Ophthalmology

Glutathione: A vital lens antioxidant

FJ Giblin

JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2000)