期刊
PREVENTIVE MEDICINE
卷 164, 期 -, 页码 -出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ypmed.2022.107229
关键词
Colorectal neoplasms; Early detection of cancer; Health communication; Mass screening; Prevention
This study aimed to test whether combining the standard invitation procedure with a pre-notification and/or an extra reminder can increase participation in colorectal cancer (CRC) screening. The results showed that the four-staged invitation procedure was the most effective, especially for the youngest age group.
This study aimed to test whether participation in colorectal cancer (CRC) screening can be increased by combining the standard invitation procedure with a pre-notification and/or an extra reminder.In a non-blinded randomised controlled trial nested in a population-based CRC screening programme employing the faecal immunochemical test, Group I received a three-staged invitation procedure (pre -notifica-tion, invitation and one reminder), Group II received a three-staged invitation procedure (invitation and two reminders) and Group III received a four-staged invitation procedure (pre-notification, invitation and two re-minders). The control group received the invitation and one reminder (usual procedure).A total of 59,041 participants were included in the analyses. Overall participation rates increased from 66.9% in the control group to 69.8% in the four-staged invitation procedure corresponding to an increase in overall participation rate of 2.9% (95% CI: 1.8 to 4.0). In the age group 50-59 years, the four-staged invitation pro-cedure increased the participation rate by 4.0% (95% CI: 2.4 to 5.6). An extra reminder increased participation with 2.7% (95% CI: 1.1; 4.2) for males compared to 1.1% (95% CI:-0.3; 2.5) for females.In conclusion, the four-staged invitation procedure was the most effective invitation procedure indicating that multiple invitation procedures are most effective, especially in the youngest age group. If a three-staged invi-tation procedure is applied, a second reminder should be preferred over a pre-notification.Trial registrationThe project was registered at ClinicalTrials.gov on 26 February 2020 and patient enrolment began in August 2020. ClinicalTrials.gov Identifier: NCT04292366.
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