Precision Medicine Approaches to Mental Health Care

Developing a more comprehensive understanding of the physiological underpinnings of mental illness, precision medicine has the potential to revolutionize psychiatric care. With recent breakthroughs in next-generation multi-omics technologies and data analytics, it is becoming more feasible to leverage multimodal biomarkers, from genetic variants to neuroimaging biomarkers, to objectify diagnostics and treatment decisions in psychiatry and improve patient outcomes. Ongoing work in precision psychiatry will parallel progress in precision oncology and cardiology to develop an expanded suite of blood- and neuroimaging-based diagnostic tests, empower monitoring of treatment efficacy over time, and reduce patient exposure to ineffective treatments. The emerging model of precision psychiatry has the potential to mitigate some of psychiatry's most pressing issues, including improving disease classification, lengthy treatment duration, and suboptimal treatment outcomes. This narrative-style review summarizes some of the emerging breakthroughs and recurring challenges in the application of precision medicine approaches to mental health care

Automated summary

By utilizing multi-modal biomarkers and advanced technologies, precision medicine has the potential to revolutionize psychiatric care by providing better diagnostics and treatment decisions. The emerging field of precision psychiatry aims to develop diagnostic tests, monitor treatment efficacy, and reduce ineffective treatments in order to mitigate challenges in mental health care. This narrative-style review summarizes the breakthroughs and challenges in applying precision medicine to mental health.