Invasive Streptococcus Gallolyticus Infections in Infants At Texas Children's Hospital: A 9-Year Retrospective Review

Streptococcus gallolyticus subsp. pasteurianus is an unusual pathogen in infants, which causes sepsis and meningitis. We describe the clinical course and treatment of 15 infants with bacteremia and/or meningitis due to S. gallolyticus. Outcomes were favorable with limited neuroimaging findings. One-third of isolates displayed reduced susceptibility to penicillin highlighting the importance of performing antimicrobial susceptibility testing in infants with meningitis.

Automated summary

This study describes the clinical course and treatment of 15 infants with bacteremia and/or meningitis caused by Streptococcus gallolyticus. The outcomes were favorable and limited neuroimaging findings were observed. The study highlights the importance of performing antimicrobial susceptibility testing in infants with meningitis.