期刊
CARBOHYDRATE RESEARCH
卷 416, 期 -, 页码 59-69出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2015.07.016
关键词
Glycolipids; Biomedicine; Cosmetic; Pharmaceutics; Detergent; Biotechnology
资金
- Tunisian Ministry of Higher Education, Scientific Research and Technology
Glycolipids, consisting of a carbohydrate moiety linked to fatty acids, are microbial surface active compounds produced by various microorganisms. They are characterized by highly structural diversity and have the ability to decrease the surface and interfacial tension at the surface and interface respectively. Rhamnolipids, trehalolipids, mannosylerythritol-lipids and cellobiose lipids are among the most popular glycolipids. Moreover, their ability to form pores and destabilize biological membrane permits their use in biomedicine as antibacterial, antifungal and hemolytic agents. Their antiviral and antitumor effects enable their use in pharmaceutic as therapeutic agents. Also, glycolipids can inhibit the bioadhesion of pathogenic bacteria enabling their use as anti-adhesive agents and for disruption of biofilm formation and can be used in cosmetic industry. Moreover, they have great potential application in industry as detergents, wetting agents and for flotation. Furthermore, glycolipids can act at the surface and can modulate enzyme activity permitting the enhancement or the inhibition of the activity of certain enzymes. (C) 2015 Elsevier Ltd. All rights reserved.
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