4.8 Article

Sulfilimines as Transformable and Retainable Directing Groups in Rhodium-Catalyzed ortho-C-H Bond Functionalization

期刊

ORGANIC LETTERS
卷 24, 期 37, 页码 6772-6776

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c02630

关键词

-

资金

  1. State Key Laboratory of Pulp and Paper Engineering [2020C02]
  2. National Natural Science Foundation of China [21971074]
  3. Natural Science Foundation of Guangdong Province [2019A1515010006, 2021A1515010159]
  4. 111 Project [B20003]

向作者/读者索取更多资源

This study demonstrates for the first time the utilization of sulfilimine as a directing group for Rh(III)-catalyzed C-H activation/annulation with intermolecular and intramolecular alkyne compounds. Sulfilimine functions as a transformable directing group and an internal oxidant in the annulation with an alkyne moiety via N-S bond cleavage. Importantly, the retention of sulfilimine as a directing group is also achieved in the Rh(III)-catalyzed ortho-alkynylation with alkyne bromides.
Shown herein is the first time that the sulfilimine is utilized as a directing group for Rh(III)-catalyzed C-H activation/ annulation with intermolecular and intramolecular alkyne com-pounds. Sulfilimine serves as a transformable directing group, an internal oxidant, in the annulation with an alkyne moiety via N-S bond cleavage. Notably, the retention of sulfilimine as a directing group is also achieved in the Rh(III)-catalyzed ortho-alkynylation with alkyne bromides.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据