期刊
ORGANIC LETTERS
卷 -, 期 -, 页码 -出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c03091
关键词
-
资金
- National Natural Science Foundation of China
- Science & Technology Innovation Program of Zhejiang Province
- [21773052]
- [22071040]
- [2018R52051]
Supramolecular asymmetric catalysis is an important field that combines supramolecular chemistry and asymmetric catalysis. By utilizing crown ether-based host-guest chemistry and chiral phosphoric acid, the catalytic reaction can be regulated, leading to improved yield and enantioselectivity of the catalyst.
Supramolecular asymmetric catalysis has arisen from the in-depth intersection of supramolecular chemistry and asymmetric catalysis due to its unique advantages in building chiral catalyst libraries and regulating performance of catalysts. Herein, we combine crown ether based host-guest chemistry with chiral phosphoric acid mediated asymmetric catalysis to actualize the supramolecular regulation of catalytic asymmetric two-component tandem acetalization reactions. By comparison with the catalytic reaction without host-guest interaction, improvement of up to 72% in yield and increases of up to 13% in enantioselectivity were acquired after addition of the alkali metal guests, which demonstrated the great advantages of this supramolecular regulation strategy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据