4.8 Article

Ublituximab versus Teriflunomide in Relapsing Multiple Sclerosis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Clinical Neurology

A phase 2 multicenter study of ublituximab, a novel glycoengineered anti-CD20 monoclonal antibody, in patients with relapsing forms of multiple sclerosis

Edward Fox et al.

Summary: The study demonstrated that Ublituximab is safe and effective in relapsing multiple sclerosis patients, leading to rapid depletion of B-cells and significant reductions in MRI activity and relapses.

MULTIPLE SCLEROSIS JOURNAL (2021)

Review Clinical Neurology

Role of B Cells in Multiple Sclerosis and Related Disorders

Giancarlo Comi et al.

Summary: Selective B-cell depletion in patients with relapsing multiple sclerosis and primary progressive MS has led to a conceptual shift in understanding the pathogenesis of MS, highlighting the essential role of B cells in both inflammatory and neurodegenerative components of the disease.

ANNALS OF NEUROLOGY (2021)

Review Clinical Neurology

Targeting B Cells to Modify MS, NMOSD, and MOGAD Part 1

Jonas Graf et al.

Summary: Ocrelizumab, rituximab, ofatumumab, ublituximab, inebilizumab, and evobrutinib are immunotherapies targeting B cell-related proteins with proven efficacy in MS and NMOSD. This review examines the role of B lymphocytes in immune-mediated pathophysiology and the clinical development of CD20 depletion, particularly the pioneering contribution of rituximab. Phase 3 and postmarketing studies are highlighted for better understanding of long-term B-cell depletion efficacy and safety aspects.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2021)

Article Medicine, General & Internal

Ofatumumab versus Teriflunomide in Multiple Sclerosis

Stephen L. Hauser et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Review Immunology

Infusion-related reactions to rituximab: frequency, mechanisms and predictors

Franciane Paul et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2019)

Review Clinical Neurology

Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis

Ralph H. B. Benedict et al.

MULTIPLE SCLEROSIS JOURNAL (2017)

Article Medicine, General & Internal

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

S. L. Hauser et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

X. Montalban et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Clinical Neurology

Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis

Ralph H. B. Benedict et al.

MULTIPLE SCLEROSIS JOURNAL (2017)

Article Clinical Neurology

Magnetic resonance imaging outcomes from a phase III trial of teriflunomide

Jerry S. Wolinsky et al.

MULTIPLE SCLEROSIS JOURNAL (2013)

Article Clinical Neurology

Diagnostic Criteria for Multiple Sclerosis: 2010 Revisions to the McDonald Criteria

Chris H. Polman et al.

ANNALS OF NEUROLOGY (2011)

Article Medicine, General & Internal

Randomized Trial of Oral Teriflunomide for Relapsing Multiple Sclerosis

Paul O'Connor et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)