4.7 Editorial Material

Are we compulsively chasing rainbows?

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Compulsive alcohol drinking in rodents is associated with altered representations of behavioral control and seeking in dorsal medial prefrontal cortex

Nicholas M. Timme et al.

Summary: This study investigates the neural activity changes underlying compulsive alcohol drinking behavior using a validated rodent model. The findings suggest that in rats with compulsive alcohol drinking, neural signals in a key decision-making brain region shift from behavioral control signals to alcohol seeking signals.

NATURE COMMUNICATIONS (2022)

Article Substance Abuse

Clinical and Neural Correlates of Reward and Relief Drinking

Elizabeth M. Burnette et al.

Summary: The study found differences between reward and relief/habit-motivated drinking behaviors, with relief/habit drinkers exhibiting higher AUD severity on clinical measures and greater activation in the dorsal striatum in response to controlled alcohol cues. These findings contribute to a better understanding of drinking behavior categorization and treatment for AUD.

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH (2021)

Article Clinical Neurology

FMRI-based prediction of naltrexone response in alcohol use disorder: a replication study

Patrick Bach et al.

Summary: The neural alcohol cue-reactivity may serve as a marker for selecting patients who benefit from naltrexone treatment, supporting its potential use in precision medicine approaches for alcohol dependence.

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

Synaptic mechanism underlying serotonin modulation of transition to cocaine addiction

Yue Li et al.

Summary: This study found that cocaine use enhances compulsive behavior by affecting serotonin levels, while this effect can be reversed by increasing serotonin levels. The presynaptic depression induced by 5-HT via 5-HT1B receptors plays a role in the bidirectional effect on behavior.

SCIENCE (2021)

Article Biology

Punishment insensitivity in humans is due to failures in instrumental contingency learning

Philip Jean-Richard-Dit-Bressel et al.

Summary: Research has shown that differences in sensitivity to punishment can impact decision-making abilities and psychopathologies. In humans, individuals who are sensitive and insensitive to punishment show similar preferences for rewards and aversion to punishments, but differ significantly in their ability to detect and learn how to control aversive outcomes.
Article Multidisciplinary Sciences

A neural substrate of compulsive alcohol use

Esi Domi et al.

Summary: Research using a footshock-punished alcohol self-administration procedure identified a subpopulation of rats showing punishment-resistant self-administration behavior, which was found to be a stable trait in a subset of rats and associated with activity in the CeA brain network. Activity of PKC delta(+) inhibitory neurons in the CeL accounted for a significant portion of variance in punishment-resistant alcohol taking, suggesting a potential therapeutic target for alcohol addiction.

SCIENCE ADVANCES (2021)

Article Biochemistry & Molecular Biology

Incubation of neural alcohol cue reactivity after withdrawal and its blockade by naltrexone

Patrick Bach et al.

ADDICTION BIOLOGY (2020)

Review Psychology, Clinical

Defining Compulsive Behavior

Judy Luigjes et al.

NEUROPSYCHOLOGY REVIEW (2019)

Article Multidisciplinary Sciences

A cortical-brainstem circuit predicts and governs compulsive alcohol drinking

Cody A. Siciliano et al.

SCIENCE (2019)

Article Psychiatry

Connectome-Based Prediction of Cocaine Abstinence

Sarah W. Yip et al.

AMERICAN JOURNAL OF PSYCHIATRY (2019)

Review Neurosciences

Behavioral and neurobiological mechanisms of punishment: implications for psychiatric disorders

Philip Jean-Richard-Dit-Bressel et al.

NEUROPSYCHOPHARMACOLOGY (2018)

Editorial Material Substance Abuse

Heterogeneity of Alcohol Use Disorder: Understanding Mechanisms to Advance Personalized Treatment

Raye Z. Litten et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2015)

Article Substance Abuse

Effects of Naltrexone on Neural and Subjective Response to Alcohol in Treatment-Seeking Alcohol-Dependent Patients

Primavera A. Spagnolo et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)

Article Neurosciences

Dissociation of psychomotor sensitization from compulsive cocaine consumption

SH Ahmed et al.

NEUROPSYCHOPHARMACOLOGY (2006)