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Kawasaki disease and MIS-C share a host immune response

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NATURE REVIEWS RHEUMATOLOGY
卷 18, 期 10, 页码 555-556

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NATURE PORTFOLIO
DOI: 10.1038/s41584-022-00820-5

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  1. Clinician-Scientist Training Program at The Hospital for Sick Children
  2. Hak-Ming and Deborah Chiu Chair in Paediatric Translational Research, Hospital for Sick Children, University of Toronto

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Multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease are hyperinflammatory disorders associated with infectious diseases. This article explores whether they are distinct syndromes or exist along a continuum, providing new insights into the host immune response.
Multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease are both hyperinflammatory disorders associated with infectious diseases, but are they distinct syndromes or do they exist along a continuum? A comparison of the host immune response in these illnesses provides surprising new insights.

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