A common activator of tissue-remodeling fibroblasts across tissues

ETS1 regulates tissue-remodeling properties of specific fibroblast subtypes in the synovium, gut and cancer and thus emerges as a novel cross-tissue therapeutic target for modulation of pathogenic fibroblast activation.

Automated summary

ETS1 regulates tissue-remodeling properties of specific fibroblast subtypes in synovium, gut, and cancer, making it a novel therapeutic target for modulating pathogenic fibroblast activation.