相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Serum Analyte Profiles Associated With Crohn's Disease and Disease Location
Gabrielle Boucher et al.
INFLAMMATORY BOWEL DISEASES (2022)
Open Targets Platform: supporting systematic drug-target identification and prioritisation
David Ochoa et al.
NUCLEIC ACIDS RESEARCH (2021)
QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis
Kwontae You et al.
SCIENCE (2021)
EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
Jasmin Maier et al.
CELL REPORTS (2021)
Prolonged Exposure to Platelet Activating Factor Transforms Breast Epithelial Cells
Vaishali Chakravarty et al.
FRONTIERS IN GENETICS (2021)
The Charming World of the Extracellular Matrix: A Dynamic and Protective Network of the Intestinal Wall
Simona Pompili et al.
FRONTIERS IN MEDICINE (2021)
Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression
Soren Mucha et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)
The fate of myofibroblasts during the development of fibrosis in Crohn's disease
Chao Li et al.
JOURNAL OF DIGESTIVE DISEASES (2020)
Immunological roles of intestinal mesenchymal cells
Carolyn A. Thomson et al.
IMMUNOLOGY (2020)
TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response
Jianwen Chen et al.
NATURE COMMUNICATIONS (2020)
Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts
Wei Zhou et al.
NATURE GENETICS (2020)
PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells
Yueli Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Neutrophilic HGF-MET Signalling Exacerbates Intestinal Inflammation
Michelle Stakenborg et al.
JOURNAL OF CROHNS & COLITIS (2020)
The relationship between intestinal goblet cells and the immune response
Mingming Zhang et al.
BIOSCIENCE REPORTS (2020)
The mesenchymal context in inflammation, immunity and cancer
Vasiliki Koliaraki et al.
NATURE IMMUNOLOGY (2020)
Incidence and prevalence of inflammatory bowel disease in UK primary care: a population-based cohort study
Thomas Joshua Pasvol et al.
BMJ OPEN (2020)
Exome sequencing and characterization of 49,960 individuals in the UK Biobank
Cristopher V. Van Hout et al.
NATURE (2020)
Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease
Laxmi Sunuwar et al.
JCI INSIGHT (2020)
A missense variant in SLC39A8 confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity
Toru Nakata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Regulatory network analysis of Paneth cell and goblet cell enriched gut organoids using transcriptomics approaches
A. Treveil et al.
MOLECULAR OMICS (2020)
Treatments for Crohn's Disease-Associated Bowel Damage: A Systematic Review
Benjamin Pariente et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)
Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism
Takayoshi Sasako et al.
NATURE COMMUNICATIONS (2019)
Function and dysfunction of plasma cells in intestine
Xue Wang et al.
CELL AND BIOSCIENCE (2019)
Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome
Gang Liu et al.
MUCOSAL IMMUNOLOGY (2019)
TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epithelium
Dorothee Birkl et al.
MUCOSAL IMMUNOLOGY (2019)
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
Christopher S. Smillie et al.
CELL (2019)
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
Jerome C. Martin et al.
CELL (2019)
SDF2-like protein 1 (SDF2L1) regulates the endoplasmic reticulum localization and chaperone activity of ERdj3 protein
Ken Hanafusa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
TLR4-RelA-miR-30a signal pathway regulates Th17 differentiation during experimental autoimmune encephalomyelitis development
Xuebin Qu et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Expression patterns common and unique to ulcerative colitis and celiac disease
Luz Maria Medrano et al.
ANNALS OF HUMAN GENETICS (2019)
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells
Alexander Agrotis et al.
AUTOPHAGY (2019)
Novel proteins that regulate cell extension formation in fibroblasts
A. Yuda et al.
EXPERIMENTAL CELL RESEARCH (2018)
C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions
Vishnu Mohanan et al.
SCIENCE (2018)
Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity
Jonathan S. Duke-Cohan et al.
SCIENCE SIGNALING (2018)
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
Manuel A. Rivas et al.
PLOS GENETICS (2018)
Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity
Jonathan S. Duke-Cohan et al.
SCIENCE SIGNALING (2018)
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease
James Kinchen et al.
CELL (2018)
The NFκB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells
Bing Tian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
Wei Zhou et al.
NATURE GENETICS (2018)
Hepatocyte Growth Factor Activator: A Proteinase Linking Tissue Injury with Repair
Tsuyoshi Fukushima et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
The UK Biobank resource with deep phenotyping and genomic data
Clare Bycroft et al.
NATURE (2018)
Mesenchymal Cells in Colon Cancer
Vasiliki Koliaraki et al.
GASTROENTEROLOGY (2017)
Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation
Tsutomu Fujimori et al.
GENES TO CELLS (2017)
T-cell activation RhoGTPase-activating protein plays an important role in TH17-cell differentiation
Norimasa Tamehiro et al.
IMMUNOLOGY AND CELL BIOLOGY (2017)
Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration
Yousef R. Badran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Hailiang Huang et al.
NATURE (2017)
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de lange et al.
NATURE GENETICS (2017)
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease
Elizaveta S. Leshchiner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cigarette smoke promotes COPD by activating platelet-activating factor receptor and inducing neutrophil autophagic death in mice
Xiao-Xi Lv et al.
ONCOTARGET (2017)
Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components
Laween Meran et al.
STEM CELLS INTERNATIONAL (2017)
Mucosal Mesenchymal Cells: Secondary Barrier and Peripheral educator for the Gut immune System
Yosuke Kurashima et al.
FRONTIERS IN IMMUNOLOGY (2017)
NF-kappa B signaling in inflammation
Ting Liu et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2017)
Model-free Estimation of Recent Genetic Relatedness
Matthew P. Conomos et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Loss of Dok-1 and Dok-2 in mice causes severe experimental colitis accompanied by reduced expression of IL-17A and IL-22
Masazumi Waseda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Epithelial-mesenchymal transition in tissue repair and fibrosis
Rivka C. Stone et al.
CELL AND TISSUE RESEARCH (2016)
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
Dalin Li et al.
GASTROENTEROLOGY (2016)
IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking
Durga Sivanesan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
David Ellinghaus et al.
NATURE GENETICS (2016)
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
Manuel A. Rivas et al.
NATURE COMMUNICATIONS (2016)
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation
Zhifang Cao et al.
IMMUNITY (2015)
FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function
Matthew G. Thompson et al.
JOURNAL OF IMMUNOLOGY (2015)
Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn's-like murine ileitis
Eoin N. McNamee et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2015)
MET is required for the recruitment of anti-tumoural neutrophils
Veronica Finisguerra et al.
NATURE (2015)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
The support of human genetic evidence for approved drug indications
Matthew R. Nelson et al.
NATURE GENETICS (2015)
TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits
Dorothee Diogo et al.
PLOS ONE (2015)
Dok1 and Dok2 proteins regulate natural killer cell development and function
Javier Celis-Gutierrez et al.
EMBO JOURNAL (2014)
Very Early Onset Inflammatory Bowel Disease Associated with Aberrant Trafficking of IL-10R1 and Cure by T Cell Replete Haploidentical Bone Marrow Transplantation
Dhaarini Murugan et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2014)
Re-thinking the functions of IgA(+) plasma cells
Jennifer L. Gommerman et al.
GUT MICROBES (2014)
Microbial Modulation of Host Immunity with the Small Molecule Phosphorylcholine
Sarah E. Clark et al.
INFECTION AND IMMUNITY (2013)
Analysis of the STAT3 interactome using in-situ biotinylation and SILAC
Conny Blumert et al.
JOURNAL OF PROTEOMICS (2013)
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
Melissa Beaudoin et al.
PLOS GENETICS (2013)
Mucosal genome-wide methylation changes in inflammatory bowel disease
James Cooke et al.
INFLAMMATORY BOWEL DISEASES (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
Manuel A. Rivas et al.
NATURE GENETICS (2011)
Role of the endothelium in inflammatory bowel diseases
Walter E. Cromer et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease
Eleonora A. M. Festen et al.
PLOS GENETICS (2011)
METAL: fast and efficient meta-analysis of genomewide association scans
Cristen J. Willer et al.
BIOINFORMATICS (2010)
Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model
Marina C. Pils et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Tiam1 and Rac1 Are Required for Platelet-activating Factor-induced Endothelial Junctional Disassembly and Increase in Vascular Permeability
Ivana I. Knezevic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor
Erik-Oliver Glocker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease
Arthur Kaser et al.
SEMINARS IN IMMUNOLOGY (2009)
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
Steven A. McCarroll et al.
NATURE GENETICS (2008)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett et al.
NATURE GENETICS (2008)
Hepatocyte growth factor promotes colonic epithelial regeneration via Akt signaling
Masami Kanayama et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
John D. Rioux et al.
NATURE GENETICS (2007)
CCR7 is critically important in intestinal lamina propria for migration of dendritic cells to mesenteric lymph nodes
MH Jang et al.
JOURNAL OF IMMUNOLOGY (2006)
Expression of chemokine receptors in normal and inflamed human intestine, tonsil, and liver - An immunohistochemical analysis with new monoclonal antibodies from the 8th international workshop and conference on human leucocyte differentiation antigens
F Autschbach et al.
CELLULAR IMMUNOLOGY (2005)
Platelet-activating factor increases VIE-cadherin tyrosine phosphorylation in mouse endothelial cells and its association with the PtdIns3′-kinase
H Hudry-Clergeon et al.
FASEB JOURNAL (2005)
Hepatocyte growth factor facilitates colonic mucosal repair in experimental ulcerative colitis in rats
Y Tahara et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases
M Chamaillard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins
L Meunier et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
分享论文
