相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Structure-based discovery of nonhallucinogenic psychedelic analogs
Dongmei Cao et al.
SCIENCE (2022)
UCSF ChimeraX: Structure visualization for researchers, educators, and developers
Eric F. Pettersen et al.
PROTEIN SCIENCE (2021)
Structural insights into the lipid and ligand regulation of serotonin receptors
Peiyu Xu et al.
NATURE (2021)
Trial of Psilocybin versus Escitalopram for Depression
Robin Carhart-Harris et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
Ling-Xiao Shao et al.
NEURON (2021)
LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1
Ramona M. Rodriguiz et al.
SCIENTIFIC REPORTS (2021)
Virtual discovery of melatonin receptor ligands to modulate circadian rhythms
Reed M. Stein et al.
NATURE (2020)
Nickel-catalysed anti-Markovnikov hydroarylation of unactivated alkenes with unactivated arenes facilitated by non-covalent interactions
Noam Saper et al.
NATURE CHEMISTRY (2020)
The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis
Simon B. Goldberg et al.
PSYCHIATRY RESEARCH (2020)
Dibenzofuranylethylamines as 5-HT2A/2C Receptor Agonists
Thirumal Yempala et al.
ACS OMEGA (2020)
Psychedelic Psychiatry's Brave New World
David Nutt et al.
CELL (2020)
Metadynamics as a Postprocessing Method for Virtual Screening with Application to the Pseudokinase Domain of JAK2
Kara J. Cutrona et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2020)
An open-source drug discovery platform enables ultra-large virtual screens
Christoph Gorgulla et al.
NATURE (2020)
TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome
Reid H. J. Olsen et al.
NATURE CHEMICAL BIOLOGY (2020)
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor
Kuglae Kim et al.
CELL (2020)
GemSpot: A Pipeline for Robust Modeling of Ligands into Cryo-EM Maps
Michael J. Robertson et al.
STRUCTURE (2020)
Ultra-large library docking for discovering new chemotypes
Jiankun Lyu et al.
NATURE (2019)
Bigger is better in virtual drug screens
David E. Gloriam
NATURE (2019)
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Dorothee Liebschner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2019)
MolProbity: More and better reference data for improved all-atom structure validation
Christopher J. Williams et al.
PROTEIN SCIENCE (2018)
Expanding the medicinal chemistry synthetic toolbox
Jonas Bostrom et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Development of an antibody fragment that stabilizes GPCR/G-protein complexes
Shoji Maeda et al.
NATURE COMMUNICATIONS (2018)
New tools for automated high-resolution cryo-EM structure determination in RELION-3
Jasenko Zivanov et al.
ELIFE (2018)
ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine
Iryna Berezniuk et al.
JOURNAL OF NEUROCHEMISTRY (2017)
In silico design of novel probes for the atypical opioid receptor MRGPRX2
Katherine Lansu et al.
NATURE CHEMICAL BIOLOGY (2017)
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Shawn Q. Zheng et al.
NATURE METHODS (2017)
5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice
Vladimir M. Pogorelov et al.
NEUROPSYCHOPHARMACOLOGY (2017)
Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group
Pierrik Lassalas et al.
ACS MEDICINAL CHEMISTRY LETTERS (2017)
Advancing Drug Discovery through Enhanced Free Energy Calculations
Robert Abel et al.
ACCOUNTS OF CHEMICAL RESEARCH (2017)
Crystal Structure of an LSD-Bound Human Serotonin Receptor
Daniel Wacker et al.
CELL (2017)
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
Christopher Southan et al.
NUCLEIC ACIDS RESEARCH (2016)
Docking Screens for Novel Ligands Conferring New Biology
John J. Irwin et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial
Stephen Ross et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2016)
ZINC 15-Ligand Discovery for Everyone
Teague Sterling et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)
Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field
Lingle Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65
Xi-Ping Huang et al.
NATURE (2015)
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
Wesley K. Kroeze et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Structure and function of serotonin G protein-coupled receptors
John D. McCorvy et al.
PHARMACOLOGY & THERAPEUTICS (2015)
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
Wesley K. Kroeze et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects
Peter Gasser et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2015)
The ChEMBL bioactivity database: an update
A. Patricia Bento et al.
NUCLEIC ACIDS RESEARCH (2014)
Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs
Herbert Y. Meltzer et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Unstabilized Azomethine Ylides for the Stereoselective Synthesis of Substituted Piperidines, Tropanes, and Azabicyclo[3.1.0] Systems
Michael A. Ischay et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Ligand Pose and Orientational Sampling in Molecular Docking
Ryan G. Coleman et al.
PLOS ONE (2013)
Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice
William C. Wetsel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structural Features for Functional Selectivity at Serotonin Receptors
Daniel Wacker et al.
SCIENCE (2013)
Proton Donor Acidity Controls Selectivity in Nonaromatic Nitrogen Heterocycle Synthesis
Simon Duttwyler et al.
SCIENCE (2013)
Serial Femtosecond Crystallography of G Protein-Coupled Receptors
Wei Liu et al.
SCIENCE (2013)
An overview of the Amber biomolecular simulation package
Romelia Salomon-Ferrer et al.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2013)
Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking
Michael M. Mysinger et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Highly Diastereoselective Synthesis of Tetrahydropyridines by a C-H Activation-Cyclization-Reduction Cascade
Simon Duttwyler et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer
Charles S. Grob et al.
ARCHIVES OF GENERAL PSYCHIATRY (2011)
PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa Predictions
Mats H. M. Olsson et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Rapid Context-Dependent Ligand Desolvation in Molecular Docking
Michael M. Mysinger et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Psychedelics and the Human Receptorome
Thomas S. Ray
PLOS ONE (2010)
Efficient Drug Lead Discovery and Optimization
William L. Jorgensen
ACCOUNTS OF CHEMICAL RESEARCH (2009)
The Expanded Biology of Serotonin
Miles Berger et al.
ANNUAL REVIEW OF MEDICINE (2009)
Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
Frank Lovering et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Vmat2 heterozygous mutant mice display a depressive-like phenotype
Masato Fukui et al.
JOURNAL OF NEUROSCIENCE (2007)
Automated electron microscope tomography using robust prediction of specimen movements
DN Mastronarde
JOURNAL OF STRUCTURAL BIOLOGY (2005)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
A model binding site for testing scoring functions in molecular docking
BQQ Wei et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Is there a difference between leads and drugs? A historical perspective
TI Oprea et al.
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2001)
The role of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors in modulating spinal nociceptive transmission in normal and carrageenan-injected rats
YQ Zhang et al.
PAIN (2001)
分享论文
