☆ 4.8 Review

Biofilm microenvironment-responsive nanoparticles for the treatment of bacterial infection

NANO TODAY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Engineering, Biomedical

Quaternized carbon quantum dots with broad-spectrum antibacterial activity for the treatment of wounds infected with mixed bacteria

Chengfei Zhao et al.

Summary: Bacterial resistance to antibiotics has become a serious global public health threat, highlighting the urgent need for new antimicrobial agents. In this study, quaternized carbon quantum dots (qCQDs) with broad-spectrum antibacterial activity were successfully synthesized. The qCQDs exhibited satisfactory antibacterial activity against both Gram-positive and Gram-negative bacteria. In rat models of wound infections, qCQDs effectively restored the weight of rats, reduced the mortality rate associated with severe infection, and promoted wound recovery and healing. Biosafety tests confirmed the absence of obvious toxic and side effects during the testing phase. Proteomics analysis revealed that qCQDs primarily targeted ribosomal proteins in Staphylococcus aureus (Gram-positive bacteria) and down-regulated proteins associated with the citrate cycle in Escherichia coli (Gram-negative bacteria). Real-time quantitative PCR confirmed the consistency between the changes in genes corresponding to these proteins and the proteomic results after qCQDs treatment, suggesting a new antibacterial mechanism of qCQDs different from previously reported carbon quantum dots with antibacterial properties.

ACTA BIOMATERIALIA (2022)

添加到收藏夹

Article Chemistry, Analytical

Single-Walled Carbon Nanotube Probes for the Characterization of Biofilm-Degrading Enzymes Demonstrated against Pseudomonas aeruginosa Extracellular Matrices

Sparsh Agarwal et al.

Summary: A novel method involving biofilm EPS-functionalized SWCNT probes was developed for rapid screening of hydrolases on EPS, with specific studies conducted on six enzymes in CF environments. Extraction of relevant parameters and confirmation of experimental results were achieved through model fitting.

ANALYTICAL CHEMISTRY (2022)

添加到收藏夹

Review Ecology

The significance of biofilms to human, animal, plant and ecosystem health

Hugo Sentenac et al.

Summary: Biofilms are matrix-enclosed communities that are dominant in microbial life on Earth, playing important roles in various environments. Despite this significance, their importance is not well understood by the general public, conservation practitioners, and policymakers. Their impact on disease transmission and environmental health remains poorly understood.

FUNCTIONAL ECOLOGY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Hollow Mesoporous Manganese Oxides: Application in Cancer Diagnosis and Therapy

Wenjing Xu et al.

Summary: Precision, minimal invasiveness, and integration of diagnosis and treatment are critical for tumor treatment. Hollow mesoporous manganese oxides nanomaterials (HM-MONs) have unique properties, such as tumor microenvironment stimuli-responsiveness, prominent catalytic activity, excellent biodegradation, and outstanding magnetic resonance imaging ability, making them promising for tumor diagnosis and therapy applications.

SMALL (2022)

添加到收藏夹

Article Optics

Orthogonal Aza-BODIPY-BODIPY dyad as heavy-atom free photosensitizer for photo-initiated antibacterial therapy

Dongliang Yang et al.

Summary: A novel halogen-free photosensitizer, NDB, was synthesized in this study. The ROS generation capability of NDB under 730 nm laser illumination was found to be 3-fold higher than that of the commercial ICG, suggesting its potential application in photo-initiated antibacterial therapy.

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES (2022)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Charge reversal nano-systems for tumor therapy

Peng Zhang et al.

Summary: This review comprehensively summarizes the recent advances in charge-reversal nanocarriers, including their roles in cellular uptake, charge-conversion mechanisms in response to specific stimuli, the relationship between chemical structure and charge reversal activity, and commonly used polymeric materials.

JOURNAL OF NANOBIOTECHNOLOGY (2022)

添加到收藏夹

Article Chemistry, Medicinal

Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms

Ke Liu et al.

Summary: This study reports synthetic routes to fluorine-containing halogenated phenazine and halogenated acridine agents and investigates their effects against Gram-positive pathogens and biofilms. The results demonstrate significant antibacterial and biofilm-killing activities of these compounds, possibly through iron starvation.

ACS INFECTIOUS DISEASES (2022)

添加到收藏夹

Article Engineering, Biomedical

An injectable and biodegradable hydrogel incorporated with photoregulated NO generators to heal MRSA-infected wounds

Xinyi Lv et al.

Summary: An injectable, degradable, and photoactivated antibacterial hydrogel (MPDA-BNN6@Gel) was developed for the treatment of infected wounds. The hydrogel could generate local hyperthermia and release large quantities of NO gas to treat the infection under laser irradiation. It was found that the hydrogel eradicated bacteria by damaging the cell membrane, genetic metabolism, and material energy. Additionally, the hydrogel promoted wound healing in vivo in the absence of laser irradiation.

ACTA BIOMATERIALIA (2022)

添加到收藏夹

Article Chemistry, Applied

Chitosan and polyhexamethylene guanidine dual-functionalized cotton gauze as a versatile bandage for the management of chronic wounds

Chao Yang et al.

Summary: In this study, a versatile medical dressing with good antibacterial, hygroscopic and moisturizing abilities was developed. The dressing showed excellent immediate and long-lasting antibacterial activity and also had good biocompatibility and cell scratch healing performances.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹

Article Chemistry, Physical

The relief of hypoxic microenvironment using an O2 self-sufficient fluorinated nanoplatform for enhanced photodynamic eradication of bacterial biofilms

Lingyun Zou et al.

Summary: The study developed oxygen-sufficient fluorinated liposomes that enhanced the photodynamic eradication of bacterial biofilms by relieving the hypoxic microenvironment and promoting ROS generation under laser irradiation. The co-delivered O-2 carrier PFH significantly improved the bactericidal capability of PDT. Lip-Ce6-PFH@O-2 showed better antibiofilm ability than Lip-Ce6, alleviated inflammation symptoms, and accelerated wound healing in a mouse model, providing a new paradigm for enhancing the therapeutic efficacy of PDT for efficient biofilm eradication.

NANO RESEARCH (2022)

添加到收藏夹

Review Materials Science, Multidisciplinary

Stimuli-responsive nanocarriers for bacterial biofilm treatme

Meng Ding et al.

Summary: Bacterial biofilm infections pose a long-standing threat to human life and health, with traditional antibiotic therapies proving ineffective in eradicating them. Stimuli-responsive nanocarriers have gained attention for their smart drug release properties, with various stimuli such as enzymes, pH levels, and external triggers proving beneficial for biofilm treatment.

RARE METALS (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Nano-bio interactions: A major principle in the dynamic biological processes of nano-assemblies

Jing Liu et al.

Summary: Controllable nano-assembly with stimuli-responsive groups is a powerful strategy for generating theranostic nanosystems in modern medicine. However, the understanding of complex interactions between nanoassemblies and biosystems is still lacking, which limits the development of this field. In this review, the authors propose a 4W1H principle to describe the dynamic biological processes, behavior, and fate of nano-assemblies, and summarize key parameters that govern effective nano-bio interactions. The effects of these parameters on ADMET processes are discussed, and challenges in evaluating nano-bio interactions of assembled nanodrugs are highlighted.

ADVANCED DRUG DELIVERY REVIEWS (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections

Weijun Xiu et al.

Summary: Traditional antibiotic treatment is not very effective against bacteria in biofilms due to their unique metabolic conditions. This study explores the use of photodynamic therapy to eliminate methicillin-resistant Staphylococcus aureus biofilms and enhance the hypoxic microenvironment, which induces anaerobic metabolism and activates the antibacterial activity of metronidazole. Additionally, the activated chemotherapy can promote the repair of biofilm-infected wounds by polarizing macrophages to a specific phenotype.

NATURE COMMUNICATIONS (2022)

添加到收藏夹

Article Engineering, Biomedical

NIR-activated nanosystems with self-modulated bacteria targeting for enhanced biofilm eradication and caries prevention

Yunjian Yu et al.

Summary: We have developed a microenvironment-activated nanoplatform for efficient targeted delivery of antimicrobial drugs to oral biofilms. The nanoplatform can penetrate biofilms and release drugs under acidic conditions, resulting in targeted drug delivery to bacteria. Under near-infrared irradiation, the nanoplatform exhibits enhanced biofilm penetration and disruption capabilities compared to drugs alone.

BIOACTIVE MATERIALS (2022)

添加到收藏夹

Article Engineering, Environmental

Near-infrared-activated nanohybrid coating with black phosphorus/zinc oxide for efficient biofilm eradication against implant-associated infections

Jiao Fang et al.

Summary: In this study, an antibacterial phototherapeutic system based on polydopamine-black phosphorus nanosheets/zinc oxide nanowires was designed to address biofilm infection of medical implants. The system exhibited remarkable photothermal therapy capability and improved antibacterial ability, effectively dispersing bacterial biofilms and killing bacteria.

CHEMICAL ENGINEERING JOURNAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

POD Nanozyme optimized by charge separation engineering for light/pH activated bacteria catalytic/photodynamic therapy

Changyu Gao et al.

Summary: This article introduces a novel Ag/Bi2MoO6 (Ag/BMO) nanozyme optimized by charge separation engineering with photoactivated sustainable peroxidase-mimicking activities and NIR-II photodynamic performance, which exhibits satisfactory bactericidal performance against MRSA.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

添加到收藏夹

Review Microbiology

Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

Jessa Marie V. Makabenta et al.

Summary: Nanomaterial-based therapies offer a promising approach to combat antibiotic-resistant bacterial infections by targeting biofilms and overcoming recalcitrant infections. Their unique size and physical properties enable them to evade existing mechanisms associated with acquired drug resistance.

NATURE REVIEWS MICROBIOLOGY (2021)

添加到收藏夹

Review Nanoscience & Nanotechnology

Intrinsicstimuli-responsivenanocarriers for smart drug delivery of antibacterial agents-Anin-depthreview of the last two decades

Nikita Devnarain et al.

Summary: Stimuli-responsive nanocarriers have become a focus of research due to their enhanced activity, improved targeted delivery, and superior potential for bacterial penetration and eradication. These nanocarriers have the ability to release drugs specifically, and hold great promise as important tools for future antibacterial therapy.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2021)

添加到收藏夹

Article Engineering, Environmental

Solvent mixing generating air bubbles as a template for polydopamine nanobowl fabrication: Underlying mechanism, nanomotor assembly and application in cancer treatment

Qichen Zhan et al.

Summary: By releasing bubbles through mixing water and water-soluble solvents to form bubble templates, polydopamine (PDA) nanobowls are fabricated and loaded with Mn(CO)(5)Br (COMn) to form nanomotors for efficient migration in cancer cells and enhanced photodynamic therapy activity.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Review Microbiology

Eradicating biofilm infections: an update on current and prospective approaches

Ronni A. G. da Silva et al.

Summary: Biofilm formation is a complex process involving multiple factors, and antibiotics are still the main choice for treating bacterial biofilm infections. However, a holistic and multi-faceted approach is needed to eliminate hard-to-treat antibiotic-resistant biofilm infections.

CURRENT OPINION IN MICROBIOLOGY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Self-Assembled Nanoparticles as Cancer Therapeutic Agents

Wei Ge et al.

Summary: Supramolecular self-assembly in nanomedicines shows promise in overcoming the limitations of current cancer therapeutic agents, with the potential to transition from the lab to clinical settings. The review summarizes recent advances in this area, covering noncovalent driving forces, classifications, design, and applications of multifunctional self-assembled nanoparticles.

ADVANCED MATERIALS INTERFACES (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Magneto-Based Synergetic Therapy for Implant-Associated Infections via Biofilm Disruption and Innate Immunity Regulation

Jiaxing Wang et al.

Summary: The study introduces a magnetic synergistic therapy for implant-associated infections, which effectively reduces the occurrence of infections by destroying microbial biofilms. This treatment method can kill sessile bacteria and trigger immune responses to prevent infection relapse.

ADVANCED SCIENCE (2021)

添加到收藏夹

Article Engineering, Biomedical

A Biofilm Microenvironment-Activated Single-Atom Iron Nanozyme with NIR-Controllable Nanocatalytic Activities for Synergetic Bacteria-Infected Wound Therapy

Qiqi Xu et al.

Summary: A novel FePN SAzyme is introduced in this study for photothermal/chemodynamic synergistic therapy of bacterial-infected wounds in the biofilm microenvironment. The nanozyme shows high efficiency, specificity, and sensitivity, and can be activated by internal and external stimuli in the biofilm, minimizing side effects on healthy tissue.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Different strategies for the lipase immobilization on the chitosan based supports and their applications

F. Rafiee et al.

Summary: Immobilized enzymes, particularly lipase on chitosan support, have attracted significant attention due to their advantages in industry and biochemistry. This review highlights the recent studies on lipase immobilization and discusses the potential solutions for current limitations.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Polymer Science

An Amphiphilic PEGylated Peptide Dendron-Gemcitabine Prodrug-Based Nanoagent for Cancer Therapy

Ning Li et al.

Summary: An amphiphilic peptide dendrimer conjugated with gemcitabine has been developed as a nano-prodrug for breast cancer therapy, showing self-assembled behavior and effective release of the drug. In vivo studies confirm the therapeutic efficacy of the drug against breast cancer, indicating potential applications for gemcitabine and other anticancer agents.

MACROMOLECULAR RAPID COMMUNICATIONS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Novel Strategies to Combat Bacterial Biofilms

Fatemeh Hemmati et al.

Summary: Biofilms are a severe problem in bacterial infection treatment, with new therapeutic approaches needed to address biofilm-related infections. Potential strategies to inhibit bacterial biofilm development include the use of antiadhesion agents, AMPs, and other methods to interfere with different phases of biofilm development.

MOLECULAR BIOTECHNOLOGY (2021)

添加到收藏夹

Article Engineering, Environmental

An overview of the use of nanozymes in antibacterial applications

Linqiang Mei et al.

Summary: The emergence of nanozymes as promising candidates for combating bacteria is driven by their combination of advantages from nanomaterials and natural enzymes, resulting in low cost, good stability, controllable size, easy preparation, multifunctionality, and superior catalytic activity, making them potent antibacterial agents with broad-spectrum antibacterial abilities and biocompatibility.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Near-infrared Aza-BODIPY Dyes Through Molecular Surgery for Enhanced Photothermal and Photodynamic Antibacterial Therapy

Qing Yu et al.

Summary: The study synthesized two near-infrared dyes with good biocompatibility in the form of nanoparticles, showing excellent photothermal conversion efficiency and reactive oxygen species production performance under 660 nm photoirradiation.

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES (2021)

添加到收藏夹

Article Biophysics

Reduction-sensitive polymeric micelles as amplifying oxidative stress vehicles for enhanced antitumor therapy

Haoran Xia et al.

Summary: Chemotherapy-photodynamic therapy (PDT)-based combination therapy, utilizing a GSH-scavenging and ROS-generating polymeric micelle (MSLP), was designed to amplify oxidative stress and enhance anticancer therapy, showing significant antitumor activity.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Nanosilver-Decorated Biodegradable Mesoporous Organosilica Nanoparticles for GSH-Responsive Gentamicin Release and Synergistic Treatment of Antibiotic-Resistant Bacteria

Haijun Li et al.

Summary: The study developed a new material, Ag-MONs@GEN, for the treatment of antibiotic-resistant bacteria, demonstrating excellent antibacterial activity against various strains through controlled release of GEN and silver ions. Furthermore, the nanoplatform showed high safety profiles in cell experiments.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Biomimetic pH/lipase dual responsive vitamin-based solid lipid nanoparticles for on-demand delivery of vancomycin

Usri H. Ibrahim et al.

Summary: In this study, a novel antibiotic nanosystem ATS was designed to enhance antibacterial efficacy and combat antimicrobial resistance. Experimental results demonstrated that ATS could serve as a potential multifunctional adjuvant for effective and targeted delivery of antibiotics.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Materials Science, Biomaterials

Ciprofloxacin conjugated gold nanorods with pH induced surface charge transformable activities to combat drug resistant bacteria and their biofilms

Meihui Yin et al.

Summary: A novel synergistic chemo-photothermal integrated antimicrobial platform was developed, showing enhanced killing efficiency against multidrug resistant bacteria (MDR) and their biofilms.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹

Review Chemistry, Physical

Polymer-Based Therapeutic Nanoagents for Photothermal-Enhanced Combination Cancer Therapy

Nan Yang et al.

Summary: Scientists have made significant efforts in cancer control, with photothermal therapy (PTT) emerging as a promising treatment method. Polymer-based PTAs play a crucial role in cancer diagnosis and therapy, offering various advantages in terms of design, synthesis, biocompatibility, and therapeutic effects.

SMALL STRUCTURES (2021)

添加到收藏夹

Article Chemistry, Physical

Reductant-Free Synthesis of MnO2 Nanosheet-Decorated Hybrid Nanoplatform for Magnetic Resonance Imaging-Monitored Tumor Microenvironment-Responsive Chemodynamic Therapy and Near-Infrared-Mediated Photodynamic Therapy

Qili Yu et al.

Summary: A smart nanoplatform was developed by combining various responsive materials for the treatment of tumor microenvironment through photodynamic therapy and chemodynamic therapy, with the therapeutic efficacy monitored using MRI.

SMALL STRUCTURES (2021)

添加到收藏夹

Review Chemistry, Physical

Polymer-Based Therapeutic Nanoagents for Photothermal-Enhanced Combination Cancer Therapy

Nan Yang et al.

Summary: Photothermal therapy (PTT) has gained considerable attention in cancer treatment for its unique features, and polymer-based photothermal agents (PTAs) have been widely employed in cancer diagnosis and PTT due to their competitive advantages, including customizable designs, controllable synthesis, excellent biocompatibility, negligible cytotoxicity, satisfactory photostability, and desirable photothermal effects.

SMALL STRUCTURES (2021)

添加到收藏夹

Review Nanoscience & Nanotechnology

Recent development of nanomedicine for the treatment of bacterial biofilm infections

Weijun Xiu et al.

Summary: This review focuses on the recent advances in nanotechnology-based strategies and nanoagents for combating bacterial biofilm infections. It discusses typical antibiofilm nanotechnologies, smart nanoagents responsive to biofilm microenvironment, and promising antibiofilm approaches, such as theranostics, biofilm structure destruction, and quorum sensing inhibition. The current challenges and future directions in antibiofilm nanotechnologies are also discussed.

VIEW (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Emerging photothermal-derived multimodal synergistic therapy in combating bacterial infections

Jingjing Huo et al.

Summary: Given the challenges of bacterial resistance and biofilm protection, photothermal therapy (PTT)-derived multimodal synergistic treatments have emerged as a promising approach to combat bacterial infections. By combining PTT with chemotherapy, photo-dynamic/catalytic therapy, immunotherapy, and sonodynamic therapy, enhanced bactericidal activity can be achieved while minimizing potential side effects.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Review Materials Science, Multidisciplinary

Advances and Prospects of Polymeric Particles for the Treatment of Bacterial Biofilms

Chang Li et al.

Summary: This article provides a detailed overview of the application of polymeric nanoparticles in the treatment of bacterial biofilms, including their ability to enter bacterial biofilms, alter chemical properties, interact with bacteria, or release drugs. The article also discusses the physiological factors of bacterial biofilms and describes different types of polymeric nanoparticles as antibiofilm therapeutics in detail. It also discusses the cytotoxicity of polymeric nanoparticles and the current challenges and future prospects of antibiofilm treatments.

ACS APPLIED POLYMER MATERIALS (2021)

添加到收藏夹

Article Materials Science, Biomaterials

Hyaluronidase-responsive phototheranostic nanoagents for fluorescence imaging and photothermal/photodynamic therapy of methicillin-resistant Staphylococcus aureus infections

Lihui Yuwen et al.

Summary: Novel phototheranostic nanoagents with hyaluronidase-responsive fluorescence imaging and photothermal/photodynamic therapy functions have been developed for effective detection and treatment of bacterial infections.

BIOMATERIALS SCIENCE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

In situ injection of dual-delivery PEG based MMP-2 sensitive hydrogels for enhanced tumor penetration and chemo-immune combination therapy

Jianqin Yan et al.

Summary: The study utilized a nuclear-targeted tetrahedral DNA nanostructure to construct a delivery system combining chemotherapy and immunotherapy, achieving successful treatment of breast cancer with significant efficacy demonstrated in both in vivo and in vitro experiments.

NANOSCALE (2021)

添加到收藏夹

Article Materials Science, Biomaterials

A photo-triggered antifungal nanoplatform with efflux pump and heat shock protein reversal activity for enhanced chemo-photothermal synergistic therapy

Dongliang Yang et al.

Summary: The newly developed photo-triggered multifunctional nanoplatform can effectively eliminate drug-resistant fungi by releasing a quorum sensing molecule and an antifungal drug, and destroying the integrity of fungal cell membrane, inhibiting the expression of drug efflux pumps and heat shock proteins, and effectively blocking the hyphal and biofilm formation of fungi.

BIOMATERIALS SCIENCE (2021)

添加到收藏夹

Review Multidisciplinary Sciences

Therapeutic strategies against bacterial biofilms

Yufang Bi et al.

Summary: The emergence of multi-drug resistance has posed a major threat to public health and the economy due to bacterial infections. The complexity of bacterial biofilms makes eliminating mature biofilms a difficult problem, requiring potent antimicrobial agents and novel antibiofilm strategies. Researchers have been making efforts in this field to inspire the design of new antibiofilm systems.

FUNDAMENTAL RESEARCH (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Approaches for the inhibition and elimination of microbial biofilms using macromolecular agents

Lewis D. Blackman et al.

Summary: Biofilms, formed by the vast majority of bacteria and fungi at interfaces, have detrimental impacts on various industries and daily life aspects, and their high tolerance towards conventional antimicrobial agents poses challenges in their removal. Innovative antibiofilm materials utilizing aqueous-soluble macromolecules have shown promising abilities to inhibit biofilm formation or eradicate organisms within established biofilms.ButtonTitles: Biofilms are complex structures formed by bacteria and fungi, posing challenges in their removal due to their high tolerance towards antimicrobial agents. New innovative antibiofilm materials utilizing aqueous-soluble macromolecules show promise in inhibiting and removing biofilms.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Dermatology

The Immune Response to Chronic Pseudomonas aeruginosa Wound Infection in Immunocompetent Mice

Johanna M. Sweere et al.

ADVANCES IN WOUND CARE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Surface Charge Switchable Supramolecular Nanocarriers for Nitric Oxide Synergistic Photodynamic Eradication of Biofilms

Dengfeng Hu et al.

ACS NANO (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Ultra-efficient Antibacterial System Based on Photodynamic Therapy and CO Gas Therapy for Synergistic Antibacterial and Ablation Biofilms

Wei Ma et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Tannic Acid-Assisted Synthesis of Biodegradable and Antibacterial Mesoporous Organosilica Nanoparticles Decorated with Nanosilver

Yue Zhang et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics

Fei Gong et al.

NANO TODAY (2020)

添加到收藏夹

Review Microbiology

Biofilm dispersion

Kendra P. Rumbaugh et al.

NATURE REVIEWS MICROBIOLOGY (2020)

添加到收藏夹

Article Chemistry, Physical

Biofilm-Responsive Polymeric Nanoparticles with Self-Adaptive Deep Penetration for In Vivo Photothermal Treatment of Implant Infection

Congyu Wang et al.

CHEMISTRY OF MATERIALS (2020)

添加到收藏夹

Review Nanoscience & Nanotechnology

Beyond Antibiotics: Photo/Sonodynamic Approaches for Bacterial Theranostics

Xin Pang et al.

NANO-MICRO LETTERS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Self-Propelled Active Photothermal Nanoswimmer for Deep-Layered Elimination of Biofilm In Vivo

Tingting Cui et al.

NANO LETTERS (2020)

添加到收藏夹

Article Microbiology

Pseudomonas Quinolone Signal-Induced Outer Membrane Vesicles Enhance Biofilm Dispersion in Pseudomonas aeruginosa

Adam C. Cooke et al.

MSPHERE (2020)

添加到收藏夹

Review Materials Science, Biomaterials

Recent advances in pH-responsive nanomaterials for anti-infective therapy

Xinyi Lv et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biofilm microenvironment activated supramolecular nanoparticles for enhanced photodynamic therapy of bacterial keratitis

Haijie Han et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Article Materials Science, Biomaterials

An acidity-responsive polyoxometalate with inflammatory retention for NIR-II photothermal-enhanced chemodynamic antibacterial therapy

Yunhao Shi et al.

BIOMATERIALS SCIENCE (2020)

添加到收藏夹

Review Chemistry, Physical

Recent Progress on Activatable Nanomedicines for Immunometabolic Combinational Cancer Therapy

Chi Zhang et al.

SMALL STRUCTURES (2020)

添加到收藏夹

Article Materials Science, Biomaterials

Enzyme-responsive turn-on nanoprobes forin situfluorescence imaging and localized photothermal treatment of multidrug-resistant bacterial infections

Xuancheng Du et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Review Nanoscience & Nanotechnology

Emerging nanobiomaterials against bacterial infections in postantibiotic era

Dengfeng Hu et al.

VIEW (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Bacteria responsive polyoxometalates nanocluster strategy to regulate biofilm microenvironments for enhanced synergetic antibiofilm activity and wound healing

Yuetong Zhang et al.

THERANOSTICS (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Microneedle Patch-Mediated Treatment of Bacterial Biofilms

Junhua Xu et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Enzyme responsive copolymer micelles enhance the anti-biofilm efficacy of the antiseptic chlorhexidine

Yassamin N. Albayaty et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Enzyme-Responsive Mesoporous Ruthenium for Combined Chemo-Photothermal Therapy of Drug-Resistant Bacteria

Yanan Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Depriving Bacterial Adhesion-Related Molecule to Inhibit Biofilm Formation Using CeO2-Decorated Metal-Organic Frameworks

Hao Qiu et al.

SMALL (2019)

添加到收藏夹

Review Microbiology

Interaction Between Staphylococcal Biofilm and Bone: How Does the Presence of Biofilm Promote Prosthesis Loosening?

Jerome Josse et al.

FRONTIERS IN MICROBIOLOGY (2019)

添加到收藏夹

Article Robotics

Catalytic antimicrobial robots for biofilm eradication

Geelsu Hwang et al.

SCIENCE ROBOTICS (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Nanoparticle-Biofilm Interactions: The Role of the EPS Matrix

Stephanie Fulaz et al.

TRENDS IN MICROBIOLOGY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mesoporous Organosilica Hollow Nanoparticles: Synthesis and Applications

Zhaogang Teng et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Review Microbiology

Biofilm-associated infection by enterococci

Jun-Hong Ch'ng et al.

NATURE REVIEWS MICROBIOLOGY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Double-slit photoelectron interference in strong-field ionization of the neon dimer

Maksim Kunitski et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Combating Biofilm Associated Infection In Vivo: Integration of Quorum Sensing Inhibition and Photodynamic Treatment based on Multidrug Delivered Hollow Carbon Nitride Sphere

Yuhuan Sun et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Nanotechnology-based antimicrobials and delivery systems for biofilm-infection control

Yong Liu et al.

CHEMICAL SOCIETY REVIEWS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

A lipase-responsive antifungal nanoplatform for synergistic photodynamic/photothermal/pharmaco-therapy of azole-resistant Candida albicans infections

Dongliang Yang et al.

CHEMICAL COMMUNICATIONS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Enzyme Mimicry for Combating Bacteria and Biofilms

Zhaowei Chen et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Bacteria-Targeting Nanoparticles with Microenvironment-Responsive Antibiotic Release To Eliminate Intracellular Staphylococcus aureus and Associated Infection

Shengbing Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹

Review Pharmacology & Pharmacy

Responsive triggering systems for delivery in chronic wound healing

Mangesh Morey et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

添加到收藏夹

Review Medicine, General & Internal

Bacterial biofilm and associated infections

Muhsin Jamal et al.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION (2018)

添加到收藏夹

Review Microbiology

Implant infections: adhesion, biofilm formation and immune evasion

Carla Renata Arciola et al.

NATURE REVIEWS MICROBIOLOGY (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Microenvironment-Responsive Magnetic Nanocomposites Based on Silver Nanoparticles/Gentamicin for Enhanced Biofilm Disruption by Magnetic Field

Xi Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Selective cancer treatment via photodynamic sensitization of hypoxia-responsive drug delivery

Hua He et al.

NANOSCALE (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Redox/pH dual-controlled release of chlorhexidine and silver ions from biodegradable mesoporous silica nanoparticles against oral biofilms

Meng-meng Lu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

添加到收藏夹

Review Food Science & Technology

Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection

Tamara Escajadillo et al.

TOXINS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Erythrocyte membrane-coated nanogel for combinatorial antivirulence and responsive antimicrobial delivery against Staphylococcus aureus infection

Yue Zhang et al.

JOURNAL OF CONTROLLED RELEASE (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Matrix metalloproteinases: The sculptors of chronic cutaneous wounds

Venkat Raghavan Krishnaswamy et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)

添加到收藏夹

Article Chemistry, Applied

Pectin-conjugated silica microcapsules as dual-responsive carriers for increasing the stability and antimicrobial efficacy of kasugamycin

Chen Fan et al.

CARBOHYDRATE POLYMERS (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Redox-Responsive Polysulfide-Based Biodegradable Organosilica Nanoparticles for Delivery of Bioactive Agents

Seyyed Pouya Hadipour Moghaddam et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine

Shengke Li et al.

CHEMICAL COMMUNICATIONS (2017)

添加到收藏夹

Review Immunology

Microenvironmental characteristics and physiology of biofilms in chronic infections of CF patients are strongly affected by the host immune response

Peter O. Jensen et al.

APMIS (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Enzyme-Sensitive and Amphiphilic PEGylated Dendrimer-Paclitaxel Prodrug-Based Nanoparticles for Enhanced Stability and Anticancer Efficacy

Ning Li et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enzyme-Responsive Polymeric Vesicles for Bacterial-Strain-Selective Delivery of Antimicrobial Agents

Yamin Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Mini-review: Biofilm responses to oxidative stress

Michela Gambino et al.

BIOFOULING (2016)

添加到收藏夹

Review Microbiology

Biofilms: an emergent form of bacterial life

Hans-Curt Flemming et al.

NATURE REVIEWS MICROBIOLOGY (2016)

添加到收藏夹

Article Cell Biology

Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections

Taylor S. Cohen et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

添加到收藏夹

Article Immunology

Nitric oxide production by polymorphonuclear leucocytes in infected cystic fibrosis sputum consumes oxygen

M. Kolpen et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)

添加到收藏夹

Article Microbiology

Hyaluronidase expression and biofilm involvement in Staphylococcus aureus UAMS-1 and its sarA, agr and sarA agr regulatory mutants

Mark E. Hart et al.

MICROBIOLOGY-SGM (2013)

添加到收藏夹

Review Dermatology

Neutrophils and Wound Repair: Positive Actions and Negative Reactions

Traci A. Wilgus et al.

ADVANCES IN WOUND CARE (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics

Aleksandar F. Radovic-Moreno et al.

ACS NANO (2012)

添加到收藏夹

Article Biotechnology & Applied Microbiology

pH, redox potential and local biofilm potential microenvironments within Geobacter sulfurreducens biofilms and their roles in electron transfer

Jerome T. Babauta et al.

BIOTECHNOLOGY AND BIOENGINEERING (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

Philana Ling Lin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

添加到收藏夹

Article Dermatology

Clinically Addressing Biofilm in Chronic Wounds

Christopher Attinger et al.

ADVANCES IN WOUND CARE (2012)

添加到收藏夹

Article Biochemistry & Molecular Biology

The Cystine/Cysteine Cycle and GSH Are Independent and Crucial Antioxidant Systems in Malignant Melanoma Cells and Represent Druggable Targets

Roberta Vene et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

添加到收藏夹

Article Microbiology

Oxidative and nitrosative stress in Staphylococcus aureus biofilm

Julio E. Arce Miranda et al.

FEMS MICROBIOLOGY LETTERS (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bacterial Toxin-Triggered Drug Release from Gold Nanoparticle-Stabilized Liposomes for the Treatment of Bacterial Infection

Dissaya Pornpattananangkul et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

添加到收藏夹

Review Microbiology

The biofilm matrix

Hans-Curt Flemming et al.

NATURE REVIEWS MICROBIOLOGY (2010)

添加到收藏夹

Article Respiratory System

Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

M. Kolpen et al.

THORAX (2010)

添加到收藏夹

Article Immunology

Biofilm formation in clinical Candida isolates and its association with virulence

Fahmi Hasan et al.

MICROBES AND INFECTION (2009)

添加到收藏夹

Article Microbiology

Role of hyaluronidase in Streptococcus intermedius biofilm

D. Pecharki et al.

MICROBIOLOGY-SGM (2008)

添加到收藏夹

Article Microbiology

Dynamics and spatial distribution of β-lactamase expression in Pseudomonas aeruginosa biofilms

N Bagge et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.