4.6 Article

Ultralong floating hydrogel raft for prolonged gastric retention

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Cheerios Effect Inspired Microbubbles as Suspended and Adhered Oral Delivery Systems

Cheng Zhao et al.

Summary: A novel microbubble carrier inspired by the Cheerios effect has been developed for durable oral drug delivery, showing stability and controllability in product fabrication. The hollow microbubbles exhibit behavior similar to Cheerios, floating in gastric juice, adhering to the stomach wall, and enhancing drug absorption. In a proof of concept study, dexamethasone-loaded hollow microbubbles were shown to remain suspended in the stomach of mice for over 1 day, demonstrating good therapeutic effect in treating lupus erythematosus. The microbubble floating system is believed to have important values in long-term oral administration.

ADVANCED SCIENCE (2021)

Review Chemistry, Multidisciplinary

Rational Design of Smart Hydrogels for Biomedical Applications

Yanyu Zhang et al.

Summary: Hydrogels are polymeric structures with high water content that play a significant role in biomedical applications. They are categorized based on composition, with intelligent hydrogels designed to respond to environmental stimuli. Applications include tissue repair, drug delivery, and cancer therapy.

FRONTIERS IN CHEMISTRY (2021)

Review Pharmacology & Pharmacy

Gastroretentive Technologies in Tandem with Controlled-Release Strategies: A Potent Answer to Oral Drug Bioavailability and Patient Compliance Implications

Napoleon-Nikolaos Vrettos et al.

Summary: Combining gastroretentive drug delivery technologies with controlled-release strategies can enhance the therapeutic efficacy of many drugs and improve patient compliance by reducing dosing frequency.

PHARMACEUTICS (2021)

Article Pharmacology & Pharmacy

Long-Acting Risperidone Dual Control System: Preparation, Characterization and Evaluation In Vitro and In Vivo

Xieguo Yan et al.

Summary: This study developed a long-acting risperidone implant system for schizophrenia treatment, which achieved stable drug release and blood concentration through evaluation indicators and mathematical modeling optimization. The optimized formulation exhibited good biocompatibility and stability in in vitro and in vivo assessments, providing a new avenue for treating schizophrenia.

PHARMACEUTICS (2021)

Article Chemistry, Multidisciplinary

Mechanism of a long-term controlled drug release system based on simple blended electrospun fibers

Jiaen Wu et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Medicine, General & Internal

Prevalence of and factors associated with primary medication non-adherence in chronic disease: A systematic review and meta-analysis

McVin Hua Heng Cheen et al.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2019)

Review Pharmacology & Pharmacy

Current State and Future Perspectives on Gastroretentive Drug Delivery Systems

Julu Tripathi et al.

PHARMACEUTICS (2019)

Review Pharmacology & Pharmacy

Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form

David H. Altreuter et al.

EXPERT OPINION ON DRUG DELIVERY (2018)

Review Pharmacology & Pharmacy

Navigating the human gastrointestinal tract for oral drug delivery: Uncharted waters and new frontiers

Mirko Koziolek et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Cell Biology

Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals

Andrew M. Bellinger et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Review Pharmacology & Pharmacy

Gastro-retentive drug delivery systems and their in vivo success: A recent update

Uttam Kumar Mandal et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Article Pharmacology & Pharmacy

Formulation of risperidone in floating microparticles to alleviate its extrapyramidal side effects

Hussein O. Ammar et al.

FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Article Multidisciplinary Sciences

Optimization and In Vivo Toxicity Evaluation of G4.5 Pamam Dendrimer-Risperidone Complexes

Maria Jimena Prieto et al.

PLOS ONE (2014)

Review Cell Biology

Aging with multimorbidity: A systematic review of the literature

Alessandra Marengoni et al.

AGEING RESEARCH REVIEWS (2011)

Review Pharmacology & Pharmacy

Recent advances and perspectives on coated alginate microspheres for modified drug delivery

Pietro Matricardi et al.

EXPERT OPINION ON DRUG DELIVERY (2008)