☆ 4.6 Review

Strategies for Improving Bioavailability, Bioactivity, and Physical-Chemical Behavior of Curcumin

MOLECULES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Polymer Science

Hollow microcapsule with pH-sensitive chitosan/polymer shell for in vitro delivery of curcumin and gemcitabine

Faeze Kazemi-Andalib et al.

Summary: The utilization of hollow structures for drug encapsulation and controlled release has gained attention. The layer-by-layer assembly of oppositely charged polymers is important, especially for pH-responsive capsules in cancer drug delivery. pH-sensitive and biodegradable capsules were prepared, showing high encapsulation and releasing efficiency for anticancer drugs and high cytotoxicity on colorectal carcinoma cells.

EUROPEAN POLYMER JOURNAL (2022)

添加到收藏夹

Article Chemistry, Physical

1H NMR spectroscopic characterization of inclusion complex of desferrioxamine B chelator and β-cyclodextrin

Calin G. Floare et al.

Summary: In this study, the complexation between DFOB and beta-CD in solution was investigated using 1H NMR spectroscopy, confirming inclusion compound formation. A 1:1 stoichiometry and association constant were determined, and theoretical molecular docking study was performed to ascertain possible conformations of the inclusion complex.

JOURNAL OF MOLECULAR STRUCTURE (2022)

添加到收藏夹

Article Food Science & Technology

Entrapment of curcumin in soy protein isolate using the pH-driven method: Nanoencapsulation and formation mechanism

Hanyu Li et al.

Summary: This study demonstrates that pH-driven method can achieve nanoencapsulation of curcumin by soybean protein isolate, with different pH values affecting the stability and encapsulation efficiency of the nanocomposites. Hydrophobic interactions promoted the formation of the nanocomposites, and curcumin had a strong static fluorescence quenching effect on SPI.

LWT-FOOD SCIENCE AND TECHNOLOGY (2022)

添加到收藏夹

Article Food Science & Technology

Encapsulation of curcumin in ZEIN-HTCC complexes: Physicochemical characterization, in vitro sustained release behavior and encapsulation mechanism

Gerui Ren et al.

Summary: The encapsulation of curcumin (CUR) in ZEIN-N-(2-hydroxy) propyl-3-trimethylammonium chitosan chloride (HTCC) complexes using antisolvent precipitation (ASP) method improved its stability and water solubility, achieving sustained release. The complexes exhibited good redispersibility and controlled release behavior, fitting into the Higuchi model. Results showed that hydrophobic interaction, hydrogen bonding, and electrostatic interactions were driving forces for complex formation, with the encapsulated CUR in an amorphous state.

LWT-FOOD SCIENCE AND TECHNOLOGY (2022)

添加到收藏夹

Article Nutrition & Dietetics

Protective effects of whey protein concentrate admixtured of curcumin on metabolic control, inflammation and oxidative stress in Wistar rats submitted to exhaustive exercise

Aline Rosignoli da Conceicao et al.

Summary: The study showed that the combination of whey protein concentrate and curcumin can reduce blood glucose levels, oxidative damage, and inflammatory responses, which helps mitigate the effects of exhaustive physical exercise in swimming.

BRITISH JOURNAL OF NUTRITION (2022)

添加到收藏夹

Article Chemistry, Applied

Binding affinity of curcumin to bovine serum albumin enhanced by pulsed electric field pretreatment

Rui Wang et al.

Summary: This study found that pulsed electric field pretreatment can increase the binding affinity between curcumin and bovine serum albumin, and improve the loading capacity and storage stability of curcumin. PEF pretreatment makes the protein structure more disordered and increases the binding affinity to curcumin.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Applied

The stability and bioavailability of curcumin loaded ?-lactalbumin nanocarriers formulated in functional dairy drink

Qimeng Wang et al.

Summary: Curcumin-loaded nanocarriers were successfully applied in functional dairy drinks, improving the stability and bioavailability of curcumin. The nanocarriers exhibited intestine-responsive release behavior and provided protection against UV light, resulting in excellent colloidal stability and enhanced perception score of stability and overall assessment.

FOOD HYDROCOLLOIDS (2022)

添加到收藏夹

Review Food Science & Technology

A review on selected pharmacological activities of Curcuma longa L

B. Jyotirmayee et al.

Summary: Turmeric, a significant spice, possesses various active biochemical activities, including anti-inflammatory, antioxidant, antibacterial, and hypoglycemic qualities. It is extensively studied in the medical industry and used for the treatment of multiple diseases.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Binding analysis of the curcumin-based synthetic alpha-glucosidase inhibitors to beta-lactoglobulin as potential vehicle carrier for antidiabetic drugs

Afsoon Yousefi et al.

Summary: This study investigated the binding properties of beta-LG with four different synthetic curcumin-based derivatives, showing high affinity between the compounds and beta-LG. Hydrophobic interactions were found to play a notable role in the protein-ligand binding, with results suggesting the binding process to be endothermic and entropy driven. The research also indicated that the protein-ligand binding was spontaneous, implying the presence of static quenching between the two molecules.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Nutrition & Dietetics

Delivery of Curcumin Using Zein-Gum Arabic-Tannic Acid Composite Particles: Fabrication, Characterization, and in vitro Release Properties

Yiquan Zhang et al.

Summary: Composite particles of zein-gum arabic-tannic acid were fabricated to deliver curcumin with improved stability and bioaccessibility. The curcumin in the composite particles showed enhanced thermal and photochemical stability, increased retention rate, higher antioxidant activity, and significantly improved bioaccessibility compared to free curcumin. Therefore, these designed particles have the potential to broaden the application of curcumin in the food industry.

FRONTIERS IN NUTRITION (2022)

添加到收藏夹

Article Nutrition & Dietetics

Fabrication and Characterization of Ultra-High-Pressure (UHP)-Induced Whey Protein Isolate/κ-Carrageenan Composite Emulsion Gels for the Delivery of Curcumin

Jiaqi Su et al.

Summary: This study fabricated whey protein isolate (WPI)/kappa-carrageenan (kappa-CG) composite emulsion gels using ultra-high-pressure (UHP) technology, which showed better physical properties and release capabilities compared to traditional thermal, acid, or enzyme processing. By adjusting the formulation and processing conditions, emulsion gels with different properties and microstructures could be obtained. Moreover, the study demonstrated the delayed release of curcumin in UHP-treated emulsion gels.

FRONTIERS IN NUTRITION (2022)

添加到收藏夹

Article Nutrition & Dietetics

Formation mechanism of binary complex based on β-lactoglobulin and propylene glycol alginate with different molecular weights: Structural characterization and delivery of curcumin

Dongdong Lin et al.

Summary: This study prepared propylene glycol alginate (PGA) molecules with different molecular weights and combined them with beta-lactoglobulin nanoparticles (beta-lgNPs) to form complexes for the delivery of curcumin. The depolymerization rate of PGA molecules depended on various factors. The complexes formation was driven by non-covalent interactions and the molecular weight of PGA influenced the micro-morphology of the complexes.

FRONTIERS IN NUTRITION (2022)

添加到收藏夹

Article Chemistry, Applied

Entrapping curcumin in the hydrophobic reservoir of rice proteins toward stable antioxidant nanoparticles

Pengcheng Xu et al.

Summary: This study prepared water-soluble curcumin-loaded nanoparticles using hydrophobic rice proteins (RPs). The curcumin was entrapped inside the hydrophobic reservoir formed by the acid-induced refolding of RPs, resulting in excellent colloidal stability and prominent antioxidant properties of the nanoparticles.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Food Science & Technology

Pea protein based nanocarriers for lipophilic polyphenols: Spectroscopic analysis, characterization, chemical stability, antioxidant and molecular docking

Xiaoge Zhang et al.

Summary: The research successfully encapsulated lipophilic polyphenols CUR, QUE, and RES into PPI nanocarriers with different loading capacities, without changing the secondary structure of PPI. Results from FTIR, DSC, and XRD confirmed the transformation of polyphenols from crystalline to amorphous state after combination with PPI. PPI effectively shielded polyphenols from UV light and thermal treatment, and improved their antioxidant activity.

FOOD RESEARCH INTERNATIONAL (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Folic acid-decorated PEGylated magnetite nanoparticles as efficient drug carriers to tumor cells overexpressing folic acid receptor

Codina Movileanu et al.

Summary: The study aimed to develop FA-functionalized magnetic nanoparticles for better internalization and targeted delivery of therapeutic agents, applicable not only for cancer treatment but also for treatment of other inflammation-associated diseases.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

COMPLEXATION OF CURCUMIN USING WHEY PROTEINS TO ENHANCE AQUEOUS SOLUBILITY, STABILITY AND ANTIOXIDANT PROPERTY

Levente Zsolt Racz et al.

Summary: This study investigated the use of whey protein concentrate to enhance the stability and solubility of curcumin. Encapsulation of curcumin-WPC complexes using spray drying and freeze drying methods showed improvements in stability and solubility. Different molar ratios and drying methods influenced the properties of the complexes, with freeze-dried samples exhibiting higher solubility. Antioxidant activity of curcumin complexes with WPC was found to be superior to vitamin C, with the 1CCM-1WPC_SD complex showing the best antioxidant properties.

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

CURCUMIN AND WHEY PROTEIN BINDING AND STRUCTURAL CHARACTERISTICS OF THEIR COMPLEX EVIDENCED BY ATOMIC FORCE MICROSCOPY

Levente Zsolt Racz et al.

Summary: The study demonstrates that whey protein can help curcumin improve water solubility and bioavailability, embedding them in a compact structure. The surface roughness of the thin films formed on adsorption depends on the ratio of pure curcumin and whey protein concentrate. This research provides strong support for the application of whey protein as an effective carrier of curcumin.

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA (2022)

添加到收藏夹

Article Engineering, Biomedical

Slow release curcumin-containing soy protein nanoparticles as anticancer agents for osteosarcoma: synthesis and characterization

Hadi Zare-Zardini et al.

Summary: Curcumin-containing soy protein nanoparticles were successfully synthesized and evaluated for their anticancer activity and drug release behavior.

PROGRESS IN BIOMATERIALS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Analysis of the interaction behavior between Nano-Curcumin and two human serum proteins: combining spectroscopy and molecular stimulation to understand protein-protein interaction

Parisa Mokaberi et al.

Summary: In this study, the effects of Nano-curcumin binding on HSA-HTF interactions were investigated through spectroscopic techniques and MD simulation. The study revealed that Nano-CUR can quench both proteins with a static mechanism and the significance of van-der-Waals forces and hydrogen bonds in the binding process. The induced conformational changes and proximity to specific residues were evaluated, showing higher binding significance in the HTF (Nano-CUR) complex.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

添加到收藏夹

Article Oncology

Synergistic Induction of Apoptosis by Quercetin and Curcumin in Chronic Myeloid Leukemia (K562) Cells: II. Signal Transduction Pathways Involved

Ergul Mutlu Altundag et al.

Summary: Flavonoids have chemo-preventive and chemotherapeutic properties, with quercetin and curcumin showing beneficial synergistic effects on human cancer cells, specifically chronic myeloid leukemia cells through various signaling pathways.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2021)

添加到收藏夹

Article Food Science & Technology

Electrospray Production of Curcumin-walnut Protein Nanoparticles

Maryam Asadi et al.

Summary: Electrospray technique was used to produce nanoparticles from walnut protein isolate for curcumin encapsulation. The addition of curcumin affected the properties of the nanoparticles. In vitro study showed limited release of curcumin in the stomach and higher antioxidant activity of curcumin-WPI NPs after digestion.

FOOD BIOPHYSICS (2021)

添加到收藏夹

Review Engineering, Chemical

Determination of mechanical properties of whey protein films during accelerated aging: Application ofFTIRprofiles and chemometric tools

Camilo Agudelo-Cuartas et al.

Summary: The study demonstrates the potential use of FTIR profiles and chemometric tools for predicting mechanical properties of whey protein-based film (WPF). The research provides a practical approach for evaluating film properties and could be beneficial for rapid monitoring and characterization of films for food packaging.

JOURNAL OF FOOD PROCESS ENGINEERING (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Silymarin is an ally against insulin resistance: A review

Karla MacDonald-Ramos et al.

Summary: Silymarin, derived from Milk thistle plant, has been historically used to treat liver disease and has shown potential benefits in cardioprotection, neuroprotection, immune modulation, and cancer. Its active component silybin possesses antioxidant, anti-inflammatory, and insulin-sensitizing properties which have been studied in clinical trials for patients with insulin resistance.

ANNALS OF HEPATOLOGY (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Mung bean protein as a promising biopolymeric vehicle for loading of curcumin: Structural characterization, antioxidant properties, and in vitro release kinetics

Mehdi Mohammadian et al.

Summary: Mung bean protein was used to load curcumin through conventional and pH-shifting methods, with the latter showing higher encapsulation efficiency; hydrophobic interactions and hydrogen bonding between curcumin and mung bean proteins were confirmed through fluorescence spectroscopy and Fourier transform infra-red analysis; XRD and DSC analysis indicated a decrease in curcumin crystallinity and predicted release mechanisms as non-Fickian diffusion or super case II transport relaxation release.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

添加到收藏夹

Article Engineering, Chemical

Microencapsulation of curcumin using coconut milk whey and Gum Arabic

Sachin Ramdas Adsare et al.

Summary: The study investigated the spray-drying of coconut whey powders with gum Arabic and curcumin, analyzing their physicochemical characteristics, functional properties, and thermogravimetric analysis. Results showed that addition of gum Arabic significantly influenced the encapsulation efficiency of curcumin and spray drying yield, and coconut whey powder was found to be more stable than gum Arabic. The study concluded that spray-drying was favorable for curcumin microencapsulation, particularly when using coconut whey powder with 5% gum Arabic.

JOURNAL OF FOOD ENGINEERING (2021)

添加到收藏夹

Article Food Science & Technology

Morphological characterization of whey protein concentrate admixture of microencapsulated curcumin by spray drying

Jaqueline Vieira Piovezana Gomes et al.

Summary: The study utilized spray drying technology to develop whey protein concentrate (WPC) and whey protein concentrate admixture of microencapsulated curcumin (TWPC), both showing spherical, irregular, particulate morphology with agglomeration points and no apparent cracks. By comparing the colorimetry values of WPC and TWPC, it was found that the addition of curcumin extract led to a tendency towards yellow coloration. The research successfully developed TWPC without altering the technological characteristics of WPC.

JOURNAL OF FOOD PROCESSING AND PRESERVATION (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural interplay between curcumin and soy protein to improve the water-solubility and stability of curcumin

Yuying Wang et al.

Summary: This study evaluated the potential of using soy protein to interact, encapsulate, and protect hydrophobic curcumin by pH-shift method, leading to the formation of SP-Cur nanoparticles with enhanced thermal and photostability. The encapsulation of curcumin into soy protein was shown to be a spontaneous reaction mainly driven by hydrophobic interaction. The spherical SP-Cur nanoparticles had a relatively small size and a high encapsulation efficiency of up to 97.43%.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Synthesis of nano-fibers containing nano-curcumin in zein corn protein and its physicochemical and biological characteristics

Narges Fereydouni et al.

Summary: The study demonstrated the successful incorporation of Nano-CUR into zein nanofibers, improving their physicochemical properties and biological activities. Different concentrations of Nano-CUR showed varying release profiles and encapsulation efficiencies in NFs, with zein/Nano-CUR 10% NFs providing the best conditions for cell proliferation.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Article Chemistry, Applied

Curcumin extracts from Curcuma Longa - Improvement of concentration, purity, and stability in food-approved and water-soluble surfactant-free microemulsions

Pierre Degot et al.

Summary: Curcumin was extracted from Curcuma Longa using a surfactant-free microemulsion, producing highly concentrated tinctures of up to 130 mg/mL curcuminoids. Water content influenced the extraction process and the purity of the extracts, with additional purification steps enhancing purity to 94%. Purification before extraction allowed for indefinite solubilization of water insoluble curcumin extracts in aqueous environments, with stability of the solutions for up to five months when kept away from natural light.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Applied

Fabrication and characterization of sunflower protein isolate nanoparticles, and their potential for encapsulation and sustainable release of curcumin

Laleh Mehryar et al.

Summary: The research investigated the effects of ethanol and methanol as desolvating agents at different temperatures on the fabrication of sunflower protein isolate (SnPI) nanoparticles, as well as the encapsulation efficiency of curcumin. Ethanol produced smaller and more uniform nanoparticles compared to methanol, with encapsulation efficiencies ranging from 39.1% to 95.4%. The release of curcumin from the nanoparticles exhibited a biphasic trend, with over 50% released in the first 2 hours due to the burst effect of the protein matrix.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Engineering, Chemical

Complexation of curcumin using proteins to enhance aqueous solubility and bioaccessibility: Pea protein vis-a-vis whey protein

Umesh Kannamangalam Vijayan et al.

Summary: This study evaluated the complexation of curcumin using pea protein isolate (PPI) and whey protein isolate (WPI) to overcome challenges such as poor aqueous solubility and limited bioaccessibility. The thermodynamic parameters indicated a hydrophobic interaction nature. While there were differences in solubility between PPI-curcumin and WPI-curcumin complexes under different conditions, both proteins showed similar bioaccessibility scores for curcumin from their respective complexes.

JOURNAL OF FOOD ENGINEERING (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

CURCUMIN-WHEY PROTEIN SOLID DISPERSION SYSTEM WITH IMPROVED SOLUBILITY AND CANCER CELL INHIBITORY EFFECT

Levente Racz et al.

Summary: A solid dispersion system containing a high amount of curcumin was prepared using whey protein concentrate by spray-drying method, showing an amorphous state with weak hydrogen bond interactions and a homogeneous microparticle morphology. The enhanced solubility of curcumin and promising antitumoral effects against skin melanoma cells suggest potential for further exploitation.

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Zein Nanoparticles Improve the Oral Bioavailability of Curcumin in Wistar Rats

Ana Brotons-Canto et al.

Summary: Curcumin is a natural compound with high antioxidant and anti-inflammatory activities, but has limited clinical application due to low solubility and rapid metabolism. Incorporating curcumin in zein nanoparticles significantly increased oral bioavailability by 9-fold compared to standard curcumin extract, and showed superior effectiveness to other bioavailability-enhanced curcumin complexes currently available. This nanoparticle-based formulation has great potential as a nutraceutical for oral curcumin administration.

PHARMACEUTICS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dimethoxycurcumin reduces proliferation and induces apoptosis in renal tumor cells more efficiently than demethoxycurcumin and curcumin

Thalita Alves Zanetti et al.

Summary: This study compared the effects of curcumin and its two analogs on human renal adenocarcinoma cells, revealing that they induce cell death through different mechanisms, with DiMC showing the highest cytotoxicity and apoptosis-inducing effects.

CHEMICO-BIOLOGICAL INTERACTIONS (2021)

添加到收藏夹

Article Chemistry, Applied

Comparison of bioactive compounds and nutrient contents in whey protein concentrate admixture of turmeric extract produced by spray drying and foam mat drying

Jaqueline Vieira Piovezana Gomes et al.

Summary: A whey protein admixture of turmeric extract was developed using spray drying (TWPC-SD) and foam mat drying (TWPC-FMD) methods. The TWPC-SD showed higher contents of total phenolics and curcumin, along with good sensory acceptability, making it a viable option for human consumption. The study also found that the vitamin C content was maintained and antioxidant capacity was increased in both TWPC samples.

FOOD CHEMISTRY (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Improving Curcumin Bioavailability: Current Strategies and Future Perspectives

Rita Tabanelli et al.

Summary: This article discusses the issue of low bioavailability of curcumin and introduces strategies to improve its bioavailability, including the use of adjuvants, complexed/encapsulated curcumin, specific curcumin formulations, and curcumin nanoparticles. Clinical trial results show that improved bioavailability leads to increased therapeutic efficacy, and advancements in nanoparticle technology hold great promise for developing curcumin-based therapeutic agents.

PHARMACEUTICS (2021)

添加到收藏夹

Review Medicine, Research & Experimental

Will curcumin nanosystems be the next promising antiviral alternatives in COVID-19 treatment trials?

Douglas Dourado et al.

Summary: Curcumin and its nanostructured systems show potential as antiviral keys for treating SARS-CoV-2, with the possibility of improving treatment efficacy by increasing bioavailability and therapeutic efficiency.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Article Chemistry, Applied

On improving bioaccessibility and targeted release of curcumin-whey protein complex microparticles in food

Qianyu Ye et al.

Summary: Spray drying enhances the complexation of curcumin with whey protein isolate, forming microparticles with improved solubility, stability, and bioaccessibility. The study suggests a strategy to incorporate hydrophobic bioactive small molecules into a food matrix to improve bioavailability and target release without affecting sensory properties.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Interaction between Curcumin and β-Casein: Multi-Spectroscopic and Molecular Dynamics Simulation Methods

Ruichen Zhao et al.

Summary: The study showed that curcumin can form a complex with beta-casein, mainly driven by electrostatic interaction. The binding energy of the complex was lower under acidic conditions compared to neutral conditions. Additionally, presence of curcumin led to a decrease in alpha-helix content and an increase in random coil content in beta-casein.

MOLECULES (2021)

添加到收藏夹

Review Food Science & Technology

Promising role of curcumin against viral diseases emphasizing COVID-19 management: A review on the mechanistic insights with reference to host-pathogen interaction and immunomodulation

Shrinjana Dhar et al.

Summary: Curcumin has garnered significant interest in medical and scientific research due to its multifaceted activity, showing promise against inflammatory diseases and virus infections. Further analysis of its cellular mechanisms is needed to understand its role in combating COVID-19.

JOURNAL OF FUNCTIONAL FOODS (2021)

添加到收藏夹

Article Food Science & Technology

Preparation of spray-dried curcumin microcapsules using a blend of whey protein with maltodextrin and gum arabica and its in-vitro digestibility evaluation

Sunil Meena et al.

Summary: The study aimed to prepare spray-dried curcumin microcapsules using a blend of whey proteins and carbohydrates, with an optimized core: wall material solids ratio of 1:2 and protein: carbohydrates ratio of 1:2. Spray drying at an inlet air temperature of 180 degrees Celsius was found to be the most suitable for drying the curcumin emulsion.

FOOD BIOSCIENCE (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

A protective effect of curcumin on cardiovascular oxidative stress indicators in systemic inflammation induced by lipopolysaccharide in rats

Somaieh Ahmadabady et al.

Summary: The study investigated the protective effect of curcumin on cardiovascular oxidative stress induced by systemic inflammation in rats. Results showed that curcumin decreased white blood cell levels, reduced oxidative stress, and improved antioxidant enzyme activity.

BIOCHEMISTRY AND BIOPHYSICS REPORTS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Isocratic high-performance liquid chromatography (HPLC) for simultaneous quantification of curcumin and piperine in a microparticle formulation containing Curcuma longa and Piper nigrum

Dewi Setyaningsih et al.

Summary: The study developed a simple HPLC method to quantify curcumin and piperine content in a solid dispersion based microparticle formulation, achieving satisfactory separation of the compounds and validating the method according to ICH guidelines.

HELIYON (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Solubility improvement of curcumin with amino acids

Anilkumar Gunnam et al.

Summary: The study focuses on enhancing the physicochemical properties of curcumin by utilizing basic amino acids and their derivatives, resulting in a significant improvement in its solubility and dissolution in a 40% ethanol-water solution. This approach opens up new possibilities for the application of curcumin in medical supplements.

CRYSTENGCOMM (2021)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Anti-fibrotic effects of curcumin and some of its analogues in the heart

Armita Mahdavi Gorabi et al.

HEART FAILURE REVIEWS (2020)

添加到收藏夹

Review Chemistry, Medicinal

Therapeutic potentials of curcumin in the treatment of glioblstoma

Zahra Shabaninejad et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Applied

Spray-drying microencapsulation of curcumin nanocomplexes with soy protein isolate: Encapsulation, water dispersion, bioaccessibility and bioactivities of curcumin

Fei-Ping Chen et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Quercetin, Epigallocatechin Gallate, Curcumin, and Resveratrol: From Dietary Sources to Human MicroRNA Modulation

Erika Cione et al.

MOLECULES (2020)

添加到收藏夹

Article Multidisciplinary Sciences

The dual role of curcumin and ferulic acid in counteracting chemoresistance and cisplatin-induced ototoxicity

Fabiola Paciello et al.

SCIENTIFIC REPORTS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Curcumin and Colorectal Cancer: From Basic to Clinical Evidences

Maria Pricci et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Nanoscience & Nanotechnology

Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications

Yan Chen et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

添加到收藏夹

Article Engineering, Chemical

The encapsulation of curcumin by whey protein: Assessment of the stability and bioactivity

Saber Solghi et al.

JOURNAL OF FOOD PROCESS ENGINEERING (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract-Influence of Physiological, Pathophysiological and Pharmaceutical Factors

Susan Hua

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Article Chemistry, Applied

Insights into protein-curcumin interactions: Kinetics and thermodynamics of curcumin and lactoferrin binding

Carini Aparecida Lelis et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Article Chemistry, Applied

Complexation with whey protein fibrils and chitosan: A potential vehicle for curcumin with improved aqueous dispersion stability and enhanced antioxidant activity

Yu Hu et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Review Food Science & Technology

Recent advances in encapsulation of curcumin in nanoemulsions: A review of encapsulation technologies, bioaccessibility and applications

Tian Jiang et al.

FOOD RESEARCH INTERNATIONAL (2020)

添加到收藏夹

Review Cell Biology

Versatile role of curcumin and its derivatives in lung cancer therapy

Milad Ashrafizadeh et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

添加到收藏夹

Article Food Science & Technology

Improving the Functional Activities of Curcumin Using Milk Proteins as Nanocarriers

Soad Taha et al.

FOODS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Formulation of More Efficacious Curcumin Delivery Systems Using Colloid Science: Enhanced Solubility, Stability, and Bioavailability

Bingjing Zheng et al.

MOLECULES (2020)

添加到收藏夹

Review Nutrition & Dietetics

A systemic review on the antioxidant and anti-inflammatory effects of resveratrol, curcumin, and dietary nitric oxide supplementation on human cardiovascular health

Melissa J. Banez et al.

NUTRITION RESEARCH (2020)

添加到收藏夹

Review Chemistry, Analytical

Compressed fluids and phytochemical profiling tools to obtain and characterize antiviral and anti-inflammatory compounds from natural sources

Patricia Poletto et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2020)

添加到收藏夹

Review Chemistry, Applied

Nanocomplexation of proteins with curcumin: From interaction to nanoencapsulation (A review)

Chuan-He Tang

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Fabrication of curcumin-zein-ethyl cellulose composite nanoparticles using antisolvent co-precipitation method

Sadaf Hasankhan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Review Virology

Curcumin as an Antiviral Agent

Morgan R. Jennings et al.

VIRUSES-BASEL (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin - piperine nutraceutical system with improved enzyme inhibition properties

Anna Stasilowicz et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Applied

Fabrication and investigation of physicochemical, food simulant release, and antioxidant properties of whey protein isolate-based films activated by loading with curcumin through the pH-driven method

Hossein Taghavi Kevij et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Article Medicine, General & Internal

Use of Curcumin in Multiple Myeloma patients intolerant of steroid therapy

Rajeev Ramakrishna et al.

CLINICAL CASE REPORTS (2020)

添加到收藏夹

Article Integrative & Complementary Medicine

Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and -independent apoptosis via Smad or Akt signaling pathways in HOS cells

Cheng Huang et al.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs

Avinash Ramrao Tekade et al.

ADVANCED PHARMACEUTICAL BULLETIN (2020)

添加到收藏夹

Letter Biochemistry & Molecular Biology

Curcumin: a Wonder Drug as a Preventive Measure for COVID19 Management

Yamuna Manoharan et al.

INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2020)

添加到收藏夹

Article Food Science & Technology

A tailored nanostructure design to protect camel casein-curcumin complex against the upper gastrointestinal tract hydrolysis using aggregated whey proteins in order to increase its antioxidant activity

Haniye Takbirgou et al.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Enhancing Curcumin Oral Bioavailability Through Nanoformulations

Vinod S. Ipar et al.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2019)

添加到收藏夹

Article Chemistry, Applied

Enhancing the aqueous solubility of curcumin at acidic condition through the complexation with whey protein nanofibrils

Mehdi Mohammadian et al.

FOOD HYDROCOLLOIDS (2019)

添加到收藏夹

Article Chemistry, Applied

Encapsulation of curcumin in zein/ caseinate/sodium alginate nanoparticles with improved physicochemical and controlled release properties

Qingguan Liu et al.

FOOD HYDROCOLLOIDS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

New insights into alpha-lactalbumin behavior upon interaction with resveratrol and curcumin by spectroscopic and molecular modeling techniques: binary and ternary system comparison

Mahtab Jahanshahtalab et al.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Applied

Modification of molecular conformation of spray-dried whey protein microparticles improving digestibility and release characteristics

Qianyu Ye et al.

FOOD CHEMISTRY (2019)

添加到收藏夹

Review Cell Biology

Demethoxycurcumin: A naturally occurring curcumin analogue for treating non-cancerous diseases

Mahdi Hatamipour et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin-sunflower protein nanoparticles-A potential antiinflammatory agent

Athahalli Honnagirigowda Sneharani

JOURNAL OF FOOD BIOCHEMISTRY (2019)

添加到收藏夹

Article Food Science & Technology

Investigation of Curcumin Water Solubility Through Emulsifying with Biocompatible Polyethylene Glycol-Based Polymers

Gulcemal Yildiz et al.

FOOD ANALYTICAL METHODS (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Curcumin Encapsulated PEGylated Nanoliposomes: A Potential Anti-Infective Therapeutic Agent

Anuj Mittal et al.

INDIAN JOURNAL OF MICROBIOLOGY (2019)

添加到收藏夹

Article Chemistry, Applied

Nano-encapsulation of curcumin using soy protein hydrolysates - tannic acid complexes regulated by photocatalysis: a study on the storage stability and in vitro release

Bei Jin et al.

JOURNAL OF MICROENCAPSULATION (2019)

添加到收藏夹

Article Infectious Diseases

Evaluation of Nano-curcumin effects on expression levels of virulence genes and biofilm production of multidrug-resistant Pseudomonas aeruginosa isolated from burn wound infection in Tehran, Iran

Aref Shariati et al.

INFECTION AND DRUG RESISTANCE (2019)

添加到收藏夹

Article Biophysics

Noncovalent interactions of bovine trypsin with curcumin and effect on stability, structure, and function

Mina Rajabi et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

添加到收藏夹

Article Food Science & Technology

Complexation of curcumin with whey protein isolate for enhancing its aqueous solubility through a solvent-free pH-driven approach

Hossein Taghavi Kevij et al.

JOURNAL OF FOOD PROCESSING AND PRESERVATION (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Application of Solid Dispersion Technique to Improve Solubility and Sustain Release of Emamectin Benzoate

Bin Bin Huang et al.

MOLECULES (2019)

添加到收藏夹

Review Nutrition & Dietetics

Dietary Curcumin: Correlation between Bioavailability and Health Potential

Michele Dei Cas et al.

NUTRIENTS (2019)

添加到收藏夹

Article Pathology

Possible curative role of curcumin and silymarin against nephrotoxicity induced by gamma-rays in rats

Nadia Abdel-Magied et al.

EXPERIMENTAL AND MOLECULAR PATHOLOGY (2019)

添加到收藏夹

Article Chemistry, Physical

Recent advances in colloidal delivery systems for nutraceuticals: A case study - Delivery by Design of curcumin

Mahesh Kharat et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

添加到收藏夹

Review Food Science & Technology

Structure activity relationship of tautomers of curcumin: a review

Sameera A. Rege et al.

UKRAINIAN FOOD JOURNAL (2019)

添加到收藏夹

Article Chemistry, Applied

Thermodynamic and kinetic analyses of curcumin and bovine serum albumin binding

Eliara Acipreste Hudson et al.

FOOD CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Applied

Modification of soy protein isolate by glutaminase for nanocomplexation with curcumin

Huan Xiang et al.

FOOD CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Applied

Protective effect of β-lactoglobulin against heat induced loss of antioxidant activity of resveratrol

Yuchen Guo et al.

FOOD CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Applied

Radical cross-linked whey protein aggregates as building blocks of non-heated cold-set gels

Farhad Alavi et al.

FOOD HYDROCOLLOIDS (2018)

添加到收藏夹

Article Chemistry, Applied

Cold gelation of curcumin loaded whey protein aggregates mixed with k-carrageenan: Impact of gel microstructure on the gastrointestinal fate of curcumin

Farhad Alavi et al.

FOOD HYDROCOLLOIDS (2018)

添加到收藏夹

Article Food Science & Technology

Effect of cellulose nanocrystals from sugarcane bagasse on whey protein isolate-based films

P. Sukyai et al.

FOOD RESEARCH INTERNATIONAL (2018)

添加到收藏夹

Article Engineering, Chemical

Assessing the potential of whey protein fibril as emulsifier

Raphaela Araujo Mantovani et al.

JOURNAL OF FOOD ENGINEERING (2018)

添加到收藏夹

Article Chemistry, Medicinal

ANTIFUNGAL ACTIVITY OF VARIOUS SPECIES AND STRAINS OF TURMERIC (CURCUMA SPP.) AGAINST FUSARIUM SOLANI SENSU LATO

Jesmin Akter et al.

PHARMACEUTICAL CHEMISTRY JOURNAL (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Curcumin and piperine loaded zein-chitosan nanoparticles: Development and in-vitro characterisation

Yucel Baspinar et al.

SAUDI PHARMACEUTICAL JOURNAL (2018)

添加到收藏夹

Review Nutrition & Dietetics

Curcumin in Liver Diseases: A Systematic Review of the Cellular Mechanisms of Oxidative Stress and Clinical Perspective

Mohammad Hosein Farzaei et al.

NUTRIENTS (2018)

添加到收藏夹

Article Food Science & Technology

Physicochemical and microstructural properties of whey protein isolate-based films with addition of pectin

K. S. Silva et al.

FOOD PACKAGING AND SHELF LIFE (2018)

添加到收藏夹

Article Fisheries

Sylimarin as hepatic protector and immunomodulator in Nile tilapia during Streptococcus agalactiae infection

Marco Shizuo Owatari et al.

FISH & SHELLFISH IMMUNOLOGY (2018)

添加到收藏夹

Article Chemistry, Applied

Bovine serum albumin nanoparticles improve the antitumour activity of curcumin in a murine melanoma model

Luciana Erzinger Alves de Camargo et al.

JOURNAL OF MICROENCAPSULATION (2018)

添加到收藏夹

Article Food Science & Technology

Effect of heat treatment on physicochemical and emulsifying properties of polymerized whey protein concentrate and polymerized whey protein isolate

Shanshan Jiang et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2018)

添加到收藏夹

Review Food Science & Technology

Delivery by Design (DbD): A Standardized Approach to the Development of Efficacious Nanoparticle- and Microparticle-Based Delivery Systems

David Julian McClements

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2018)

添加到收藏夹

Review Food Science & Technology

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

Betul Kocaadam et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Fabrication of biodegradable PEG-PLA nanospheres for solubility, stabilization, and delivery of curcumin

Hongying Liang et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2017)

添加到收藏夹

Article Chemistry, Applied

Recent progress in hydrogel delivery systems for improving nutraceutical bioavailability

David Julian McClements

FOOD HYDROCOLLOIDS (2017)

添加到收藏夹

Article Immunology

Immunomodulatory activities of curcumin-stabilized silver nanoparticles: Efficacy as an antiretroviral therapeutic

Rakesh Kumar Sharma et al.

IMMUNOLOGICAL INVESTIGATIONS (2017)

添加到收藏夹

Article Agriculture, Multidisciplinary

Physical and Chemical Stability of Curcumin in Aqueous Solutions and Emulsions: Impact of pH, Temperature, and Molecular Environment

Mahesh Kharat et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

添加到收藏夹

Article Chemistry, Physical

A spectroscopic study on stability of curcumin as a function of pH in silica nanoformulations, liposome and serum protein

Beena Jain

JOURNAL OF MOLECULAR STRUCTURE (2017)

添加到收藏夹

Article Food Science & Technology

Preparation of curcumin-loaded emulsion using high pressure homogenization: Impact of oil phase and concentration on physicochemical stability

Peihua Ma et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2017)

添加到收藏夹

Article Physics, Atomic, Molecular & Chemical

The mechanism of the interaction between curcumin and bovine serum albumin using fluorescence spectrum

Changchun Hao et al.

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Binding behaviors and structural characteristics of ternary complexes of β-lactoglobulin, curcumin, and fatty acids

Jingwen Liu et al.

RSC ADVANCES (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin suppresses gastric cancer by inhibiting gastrin-mediated acid secretion

Shufen Zhou et al.

FEBS OPEN BIO (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Microparticles Containing Curcumin Solid Dispersion: Stability, Bioavailability and Anti-Inflammatory Activity

C. C. C. Teixeira et al.

AAPS PHARMSCITECH (2016)

添加到收藏夹

Article Chemistry, Physical

Natural emulsifiers - Biosurfactants, phospholipids, biopolymers, and colloidal particles: Molecular and physicochemical basis of functional performance

David Julian McClements et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2016)

添加到收藏夹

Article Chemistry, Applied

One-pot nanoparticulation of potentially bioactive peptides and gallic acid encapsulation

Himan Nourbakhsh et al.

FOOD CHEMISTRY (2016)

添加到收藏夹

Article Food Science & Technology

Impact of stirring speed on β-lactoglobulin fibril formation

Shy Kai Ng et al.

FOOD SCIENCE AND BIOTECHNOLOGY (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

Preparation and Characterization of PEG-albumin-curcumin Nanoparticles Intended to Treat Breast Cancer

R. Thadakapally et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Cold-set hydrogels made of whey protein nanofibrils with different divalent cations

Mehdi Mohammadian et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

添加到收藏夹

Review Medicine, Research & Experimental

Determining whether curcumin degradation/condensation is actually bioactivation (Review)

Jerzy Jankun et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)

添加到收藏夹

Review Pharmacology & Pharmacy

Oral bioavailability of curcumin: problems and advancements

Weidong Liu et al.

JOURNAL OF DRUG TARGETING (2016)

添加到收藏夹

Review Biochemistry & Molecular Biology

Curcumin and Resveratrol in the Management of Cognitive Disorders: What Is the Clinical Evidence?

Gabriela Mazzanti et al.

MOLECULES (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Counting on natural products for drug design

Tiago Rodrigues et al.

NATURE CHEMISTRY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Neuroprotective effect of curcumin-loaded lactoferrin nano particles against rotenone induced neurotoxicity

V. Satish Bollimpelli et al.

NEUROCHEMISTRY INTERNATIONAL (2016)

添加到收藏夹

Review Cell Biology

Overview of the Role of Vanillin on Redox Status and Cancer Development

Daniel Pereira Bezerra et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

A Spectroscopic Approach to Investigate the Molecular Interactions between the Newly Approved Irreversible ErbB blocker Afatinib and Bovine Serum Albumin

Amer M. Alanazi et al.

PLOS ONE (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multispectroscopic analysis and molecular modeling to investigate the binding of beta lactoglobulin with curcumin derivatives

Sanhita Maity et al.

RSC ADVANCES (2016)

添加到收藏夹

Article Oncology

Curcumin Sensitizes Silymarin to Exert Synergistic Anticancer Activity in Colon Cancer Cells

Amanda Montgomery et al.

JOURNAL OF CANCER (2016)

添加到收藏夹

Review Oncology

Curcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast Cancer

Amol Shindikar et al.

JOURNAL OF ONCOLOGY (2016)

添加到收藏夹

Review Orthopedics

Therapeutic actions of curcumin in bone disorders

Ramin Rohanizadeh et al.

BONEKEY REPORTS (2016)

添加到收藏夹

Article Biophysics

Fabrication of amorphous curcumin nanosuspensions using β-lactoglobulin to enhance solubility, stability, and bioavailability

N. P. Aditya et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2015)

添加到收藏夹

Article Biophysics

Inter-domain helix h10(DOMI)-h1(DOMII) is important in the molecular interaction of bovine serum albumin with curcumin: spectroscopic and computational analysis

Dhakaram Pangeni et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2015)

添加到收藏夹

Article Food Science & Technology

Nanocomplexation of soy protein isolate with curcumin: Influence of ultrasonic treatment

Fei-Ping Chen et al.

FOOD RESEARCH INTERNATIONAL (2015)

添加到收藏夹

Article Materials Science, Biomaterials

Study on the interactions of trans-resveratrol and curcumin with bovine α-lactalbumin by spectroscopic analysis and molecular docking

Fakhrossadat Mohammadi et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro

Jian-Ye Zhang et al.

MOLECULES (2015)

添加到收藏夹

Review Medicine, Research & Experimental

Biological and therapeutic activities, and anticancer properties of curcumin (Review)

Donatella Perrone et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors

Rajashri Sridharan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

添加到收藏夹

Article Chemistry, Applied

Curcumin-β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application

Camila Sampaio Mangolim et al.

FOOD CHEMISTRY (2014)

添加到收藏夹

Article Agriculture, Multidisciplinary

Insight into Curcumin-Loaded β-Lactoglobulin Nanoparticles: Incorporation, Particle Disintegration, and Releasing Profiles

Zi Teng et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Analytical

Tryptophan 19 residue is the origin of bovine β-lactog1obu1in fluorescence

Jihad Rene Albani et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Icariin Is A PPARα Activator Inducing Lipid Metabolic Gene Expression in Mice

Yuan-Fu Lu et al.

MOLECULES (2014)

添加到收藏夹

Review Biochemistry & Molecular Biology

The Chemistry of Curcumin: From Extraction to Therapeutic Agent

Kavirayani Indira Priyadarsini

MOLECULES (2014)

添加到收藏夹

Article Chemistry, Physical

pH-driven encapsulation of curcumin in self-assembled casein nanoparticles for enhanced dispersibility and bioactivity

Kang Pan et al.

SOFT MATTER (2014)

添加到收藏夹

Article Oncology

Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas

Laura Masuelli et al.

ONCOTARGET (2014)

添加到收藏夹

Review Biotechnology & Applied Microbiology

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

Soheil Zorofchian Moghadamtousi et al.

BIOMED RESEARCH INTERNATIONAL (2014)

添加到收藏夹

Review Endocrinology & Metabolism

Anti-Hyperglycemic and Insulin Sensitizer Effects of Turmeric and Its Principle Constituent Curcumin

Zeinab Ghorbani et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (2014)

添加到收藏夹

Review Pharmacology & Pharmacy

Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

Subash C. Gupta et al.

AAPS JOURNAL (2013)

添加到收藏夹

Article Biophysics

Pharmacokinetics of curcumin-loaded PLGA and PLGA-PEG blend nanoparticles after oral administration in rats

Najeh Maissar Khalil et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2013)

添加到收藏夹

Article Neurosciences

Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century

Wing-Hin Lee et al.

CURRENT NEUROPHARMACOLOGY (2013)

添加到收藏夹

Article Pharmacology & Pharmacy

Bioactivity of Turmeric-derived Curcuminoids and Related Metabolites in Breast Cancer

Laura Wright et al.

CURRENT PHARMACEUTICAL DESIGN (2013)

添加到收藏夹

Article Chemistry, Applied

Binding of curcumin to β-lactoglobulin and its effect on antioxidant characteristics of curcumin

Ming Li et al.

FOOD CHEMISTRY (2013)

添加到收藏夹

Article Agriculture, Multidisciplinary

Enhanced Dispersibility and Bioactivity of Curcumin by Encapsulation in Casein Nanocapsules

Kang Pan et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

添加到收藏夹

Article Infectious Diseases

Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella Typhimurium and Salmonella Typhi

Sandhya A. Marathe et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Probing the binding sites of resveratrol, genistein, and curcumin with milk β-lactoglobulin

C. D. Kanakis et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Inclusion of α-lipoic acid in β-cyclodextrin. Physical-chemical and structural characterization

Csaba-Pal Racz et al.

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY (2013)

添加到收藏夹

Article Oncology

Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells

Qin Du et al.

ONCOLOGY REPORTS (2013)

添加到收藏夹

Article Plant Sciences

Synergistic antibacterial effect of curcumin against methicillin-resistant Staphylococcus aureus

Su-Hyun Mun et al.

PHYTOMEDICINE (2013)

添加到收藏夹

Article Engineering, Biomedical

Multifunctional particles for melanoma-targeted drug delivery

Aniket S. Wadajkar et al.

ACTA BIOMATERIALIA (2012)

添加到收藏夹

Article Chemistry, Multidisciplinary

Structure of the inclusion complex of β-cyclodextrin with lipoic acid from laboratory powder diffraction data

Csaba-Pal Racz et al.

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE (2012)

添加到收藏夹

Article Pharmacology & Pharmacy

PEGylation: An Approach for Drug Delivery. A Review

Aviral Jain et al.

CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS (2012)

添加到收藏夹

Article Thermodynamics

Determination of the solubility, dissolution enthalpy and entropy of icariin in water, ethanol, and methanol

Na Wang et al.

FLUID PHASE EQUILIBRIA (2012)

添加到收藏夹

Article Chemistry, Applied

Heating of milk alters the binding of curcumin to casein micelles. A fluorescence spectroscopy study

S. Rahimi Yazdi et al.

FOOD CHEMISTRY (2012)

添加到收藏夹

Article Chemistry, Applied

Complexation of curcumin with soy protein isolate and its implications on solubility and stability of curcumin

Arun Tapal et al.

FOOD CHEMISTRY (2012)

添加到收藏夹

Article Orthopedics

Icariin: a potential promoting compound for cartilage tissue engineering

D. Li et al.

OSTEOARTHRITIS AND CARTILAGE (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Protective Effect of Curcumin on Pulmonary and Cardiovascular Effects Induced by Repeated Exposure to Diesel Exhaust Particles in Mice

Abderrahim Nemmar et al.

PLOS ONE (2012)

添加到收藏夹

Article Reproductive Biology

Reproductive effects of a pegylated curcumin

Caitlin J. Murphy et al.

REPRODUCTIVE TOXICOLOGY (2012)

添加到收藏夹

Article Obstetrics & Gynecology

Effects of curcumin and demethoxycurcumin on amyloid-β precursor and tau proteins through the internal ribosome entry sites: A potential therapeutic for Alzheimer's disease

Oliver B. Villafiores et al.

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY (2012)

添加到收藏夹

Review Multidisciplinary Sciences

A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers

Ghanshyam B. Dudhatra et al.

SCIENTIFIC WORLD JOURNAL (2012)

添加到收藏夹

Article Pharmacology & Pharmacy

Statistically designed enzymatic hydrolysis of an icariin/β-cyclodextrin inclusion complex optimized for production of icaritin

Xin Jin et al.

ACTA PHARMACEUTICA SINICA B (2012)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin and Liver Cancer: A Review

Altaf S. Darvesh et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2011)

添加到收藏夹

Article Chemistry, Applied

β-Lactoglobulin and WPI aggregates: Formation, structure and applications

Taco Nicolai et al.

FOOD HYDROCOLLOIDS (2011)

添加到收藏夹

Article Agriculture, Multidisciplinary

Physical Properties, Molecular Structures, and Protein Quality of Texturized Whey Protein Isolate: Effect of Extrusion Temperature

Phoebe X. Qi et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)

添加到收藏夹

Article Nanoscience & Nanotechnology

Curcumin-Loaded Lipid and Polymeric Nanocapsules Stabilized by Nonionic Surfactants: An In Vitro and In Vivo Antitumor Activity on B16-F10 Melanoma and Macrophage Uptake Comparative Study

Leticia Mazzarino et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2011)

添加到收藏夹

Review Biochemistry & Molecular Biology

Multitargeting by curcumin as revealed by molecular interaction studies

Subash C. Gupta et al.

NATURAL PRODUCT REPORTS (2011)

添加到收藏夹

Review Integrative & Complementary Medicine

Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy

Murielle Mimeault et al.

CHINESE MEDICINE (2011)

添加到收藏夹

Article Oncology

Effect of imatinib therapy with and without turmeric powder on nitric oxide levels in chronic myeloid leukemia

Veena S Ghalaut et al.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

Antifungal curcumin induces reactive oxygen species and triggers an early apoptosis but prevents hyphae development by targeting the global repressor TUP1 in Candida albicans

Monika Sharma et al.

BIOSCIENCE REPORTS (2010)

添加到收藏夹

Article Oncology

Dietary quercetin, quercetin-gene interaction, metabolic gene expression in lung tissue and lung cancer risk

Tram Kim Lam et al.

CARCINOGENESIS (2010)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis

Monika Sharma et al.

FEMS YEAST RESEARCH (2010)

添加到收藏夹

Article Agriculture, Multidisciplinary

Interaction of Curcumin with β-Lactoglobulin-Stability, Spectroscopic Analysis, and Molecular Modeling of the Complex

Athahalli H. Sneharani et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)

添加到收藏夹

Article Chemistry, Physical

Resveratrol, Genistein, and Curcumin Bind Bovine Serum Albumin

P. Bourassa et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2010)

添加到收藏夹

Article Endocrinology & Metabolism

Combined Inhibitory Effects of Soy Isoflavones and Curcumin on the Production of Prostate-Specific Antigen

Hisamitsu Ide et al.

PROSTATE (2010)

添加到收藏夹

Article Neurosciences

Curcumin blocks brain tumor formation

Sudarshana Purkayastha et al.

BRAIN RESEARCH (2009)

添加到收藏夹

Article Food Science & Technology

Degradation of bioactive spice compound: curcumin during domestic cooking

D. Suresh et al.

EUROPEAN FOOD RESEARCH AND TECHNOLOGY (2009)

添加到收藏夹

Article Oncology

Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice

Narayanan K. Narayanan et al.

INTERNATIONAL JOURNAL OF CANCER (2009)

添加到收藏夹

Article Engineering, Chemical

Influence of spelt bran on the physical properties of WPI composite films

M. Mastromatteo et al.

JOURNAL OF FOOD ENGINEERING (2009)

添加到收藏夹

Article Pharmacology & Pharmacy

Polyethylene Glycosylated Curcumin Conjugate Inhibits Pancreatic Cancer Cell Growth through Inactivation of Jab1

Jun Li et al.

MOLECULAR PHARMACOLOGY (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Interaction of Curcumin and Diacetylcurcumin with the Lipocalin Member β-Lactoglobulin

Fakhrossadat Mohammadi et al.

PROTEIN JOURNAL (2009)

添加到收藏夹

Article Chemistry, Medicinal

Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo

Lian Yu Guo et al.

ARCHIVES OF PHARMACAL RESEARCH (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

Dipti Rai et al.

BIOCHEMICAL JOURNAL (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Investigating the binding of curcumin derivatives to bovine serum albumin

Bijaya Ketan Sahoo et al.

BIOPHYSICAL CHEMISTRY (2008)

添加到收藏夹

Review Biochemistry & Molecular Biology

Curcumin: From ancient medicine to current clinical trials

H. Hatcher et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

添加到收藏夹

Article Oncology

Phase II trial of curcumin in patients with advanced pancreatic cancer

Navneet Dhillon et al.

CLINICAL CANCER RESEARCH (2008)

添加到收藏夹

Article Food Science & Technology

Properties of protein fibrils in whey protein isolate solutions: Microstructure, flow behaviour and gelation

C. Akkermans et al.

INTERNATIONAL DAIRY JOURNAL (2008)

添加到收藏夹

Review Pharmacology & Pharmacy

Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs

Teofilo Vasconcelos et al.

DRUG DISCOVERY TODAY (2007)

添加到收藏夹

Article Pharmacology & Pharmacy

Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products

Regina Appiah-Opong et al.

TOXICOLOGY (2007)

添加到收藏夹

Review Food Science & Technology

Bovine whey proteins - Overview on their main biological properties

Ana R. Madureira et al.

FOOD RESEARCH INTERNATIONAL (2007)

添加到收藏夹

Article Pharmacology & Pharmacy

Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system

Wei Wu et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2006)

添加到收藏夹

Article Biochemistry & Molecular Biology

Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFKB and AP-1 translocation and modulation of apoptosis

CS Divya et al.

MOLECULAR CARCINOGENESIS (2006)

添加到收藏夹

Article Biochemical Research Methods

Using circular dichroism spectra to estimate protein secondary structure

Norma J. Greenfield

NATURE PROTOCOLS (2006)

添加到收藏夹

Article Chemistry, Applied

Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin

GK Jayaprakasha et al.

FOOD CHEMISTRY (2006)

添加到收藏夹

Article Immunology

Immunomodulatory effects of curcumin

VS Yadav et al.

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2005)

添加到收藏夹

Article Chemistry, Medicinal

Development of clinical dosage forms for a poorly water soluble drug I: Application of polyethylene glycol-polysorbate 80 solid dispersion carrier system

RM Dannenfelser et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2004)

添加到收藏夹

Article Agriculture, Multidisciplinary

Fungicidal property of Curcuma longa L. rhizome-derived curcumin against phytopathogenic fungi in a greenhouse

MK Kim et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Effect of pegylation on pharmaceuticals

JM Harris et al.

NATURE REVIEWS DRUG DISCOVERY (2003)

添加到收藏夹

Article Oncology

Curcumin exerts multiple suppressive effects on human breast carcinoma cells

ZM Shao et al.

INTERNATIONAL JOURNAL OF CANCER (2002)

添加到收藏夹

Article Biochemistry & Molecular Biology

Characterization of pH-induced transitions of β-lactoglobulin:: Ultrasonic, densimetric, and spectroscopic studies

N Taulier et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)

添加到收藏夹

Article Food Science & Technology

Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats

SE Chuang et al.

FOOD AND CHEMICAL TOXICOLOGY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.