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Robert Vianello et al.
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J. Reniers et al.
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Eva Stjernschantz et al.
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Jucelia J. Fortunato et al.
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Se-Young Son et al.
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Dinara Jaqueline Moura et al.
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Erik C. Ralph et al.
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M. A. Akyuz et al.
JOURNAL OF NEURAL TRANSMISSION (2007)
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Rihui Cao et al.
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Antidepressant-like effect of harmane and other β-carbolines in the mouse forced swim test
Davood Farzin et al.
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SS Erdem et al.
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T Herraiz et al.
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MMH van Lipzig et al.
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K Castagnoli et al.
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T Herraiz
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The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic β-cells
PE Squires et al.
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Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome
C Ancolio et al.
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J Åqvist et al.
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JM Boeira et al.
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Triplet state studies of β-carbolines
AP Varela et al.
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SM Husbands et al.
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KA Kurtz et al.
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Binding of β-carbolines and related agents at serotonin (5-HT2 and 5-HT1A), dopamine (D2) and benzodiazepine receptors
RA Glennon et al.
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K Pari et al.
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