期刊
MATERIALS CHEMISTRY AND PHYSICS
卷 290, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.matchemphys.2022.126618
关键词
Mesoporous silica; Nano -metal oxide; Antibacterial properties; Inhibition zone; Minimal inhibitory concentration
资金
- Science Technology Program of Guangzhou, China [201903010011]
- International Science and Technology Cooperation Project of Guang- dong Province [2021A050530073]
- Innovation Team of Modern Agricultural Industry Technology System of Guangdong Prov- ince [2019KJ140]
- Innovation Team Project by the Depart- ment of Education of Guangdong Province [2018KCXTD015]
- Guangdong University Key Laboratory for Substanable Control of Fruit and Vegetable Diseases and Pests [2020KSYS005]
A one-pot method was proposed in this work to prepare polydopamine-coated mesoporous silica-supported nano-metal oxide composites with good antibacterial properties. The composites showed a regular spherical shape with nano-metal oxides formed in the pores of mesoporous silica. Among them, MSN-C/ZnO and MSN-C/CuZnO exhibited better antibacterial performance and lower minimal inhibitory concentration. Therefore, these composites have potential applications as effective antibacterial products in the medical field.
Bacterial infections are recognized as a serious health issue in the world. Nano-zinc oxide (nano-ZnO) is considered as an antibacterial material because of its broad-spectrum bactericidal properties. In this work, a one-pot method to prepare nano-metal oxide-loaded composites based on polydopamine (PDA)-coated mesoporous silica (MSN/ZnO, MSN/CuZnO, MSN-C/ZnO, MSN-C/CuZnO) with good antibacterial properties was proposed. The results showed that the morphology of the composites had a regular spherical shape with an average particle size of 100 nm. And nano-metal oxides were formed in the pore of mesoporous silica with a diameter of 5 nm. Strikingly, the inhibition zone diameters towards E. coli of MSN-C/ZnO and MSN-C/CuZnO showed better antibacterial performance, were 35.40 +/- 0.01 mm and 33.20 +/- 0.01 mm, respectively. Besides, it was found that, the minimal inhibitory concentration (MIC) value of such nano-metal oxide-loaded composites were 0.625 mg/mL. Therefore, these mesoporous silica-supported nano-metal oxide composites can be used as favorable and effective antibacterial products for advanced and potential applications.
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