4.7 Article

Open-source library of tissue engineering scaffolds

期刊

MATERIALS & DESIGN
卷 223, 期 -, 页码 -

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.matdes.2022.111154

关键词

Tissue engineering; Biofabrication; Additive manufacturing; Virtual and rapid prototyping; Open-source medical devices; Biomaterials; Bioinspiration and biomimetics; FAIR data principles

资金

  1. European Union [953134]

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The field of tissue engineering could benefit from implementing standards to enhance the repeatability and comparability of research results. An internationally accepted library of scaffold models would be valuable for comparing materials and manufacturing technologies. An open-source scaffold library has been developed, providing comprehensive blueprints and adhering to the FAIR data principles.
Tissue engineering as a field may benefit from progressively implementing and spreading the use of stan-dards, conceived to support the repeatability, replicability and efficient comparing of research results among experts in the field worldwide. Considering that scaffolds play a fundamental role in many tissue engineering strategies, it would be interesting to count with an internationally accepted set of geome-tries, acting as a library of lattices, porous materials and scaffolding structures, which could be employed for comparative purposes among materials and manufacturing technologies under development. To this end, an open-source library of tissue engineering scaffolds has been implemented. This library stands out for providing a comprehensive collection of scaffolds blueprints, designed considering the specific fea-tures of most additive manufacturing technologies applicable to tissue engineering and biofabrication. Besides, the library has been developed focusing on FAIR data principles along the development, for pro-moting: Findability, Accessibility, Interoperability and Reusability. The scaffolds are shared as open -source medical devices with the necessary documentation for facilitating their application. Similar initia-tives may be synergically integrated towards an ISO standard on tissue engineering scaffolds.(c) 2022 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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