期刊
CARBOHYDRATE POLYMERS
卷 116, 期 -, 页码 223-228出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2014.07.059
关键词
TEMPO-oxidization; Bacterial cellulose; Alginate; Cell encapsulation
资金
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [2013023612]
TEMPO-oxidized bacterial cellulose (TOBC)-sodium alginate (SA) composites were prepared to improve the properties of hydrogel for cell encapsulation. TOBC fibers were obtained using a TEMPO/NaBr/NaClO system at pH 10 and room temperature. The fibrillated TOBCs mixed with SA were cross-linked in the presence of Ca2+ solution to form hydrogel composites. The compression strength and chemical stability of the TOBC/SA composites were increased compared with the SA hydrogel, which indicated that TOBC performed an important function in enhancing the structural, mechanical and chemical stability of the composites. Cells were successfully encapsulated in the TOBC/SA composites, and the viability of cells was investigated. TOBC/SA composites can be a potential candidate for cell encapsulation engineering. (C) 2014 Elsevier Ltd. All rights reserved.
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