☆ 4.7 Article

Antioxidant Activity of Gracilaria lemaneiformis Polysaccharide Degradation Based on Nrf-2/Keap-1 Signaling Pathway in HepG2 Cells with Oxidative Stress Induced by H2O2

MARINE DRUGS (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Enterocyte synthesizes and secrets uric acid as antioxidant to protect against oxidative stress via the involvement of Nrf pathway

Minghui Wang et al.

Summary: This study evaluated the synthesis and secretion of uric acid (UA) as an antioxidant in the gut and explored the regulation of the Nrf2 pathway on UA secretion and transport. The activation of Nrf2 was found to be involved in the transportation and secretion of UA.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

添加到收藏夹

Article Immunology

Probucol attenuates NF-ΚB/NLRP3 signalling and augments Nrf-2 mediated antioxidant defence in nerve injury induced neuropathic pain

Kalyani Derangula et al.

Summary: In this study, we investigated the pharmacological effect of probucol in a model of sciatic nerve-induced neuropathic pain. We found that probucol significantly attenuated behavioral, biochemical, and functional deficits through modulation of the NF-κB/NLRP3 signaling pathway and Nrf-2 pathway, highlighting its dual anti-inflammatory and antioxidant effects.

INTERNATIONAL IMMUNOPHARMACOLOGY (2022)

添加到收藏夹

Article Chemistry, Medicinal

Optimized Degradation and Inhibition of α-glucosidase Activity by Gracilaria lemaneiformis Polysaccharide and Its Production In Vitro

Xiaoshan Long et al.

Summary: Gracilaria lemaneiformis polysaccharide (GLP) was degraded by hydrogen peroxide combined with vitamin C (H2O2-Vc) to produce a new product called GLP-HV. The chemical characteristics and in vitro activities of GLP-HV and its degradation products were assessed.

MARINE DRUGS (2022)

添加到收藏夹

Article Chemistry, Applied

Mechanism of viscosity reduction of okra pectic polysaccharide by ascorbic acid

Xiumei Zhu et al.

Summary: This study investigated the effects of ascorbic acid treatment on the viscosity and structural properties of okra pectic polysaccharide, and found that it was related to the formation of hydroxyl radicals. The findings provide recommendations for the application of okra pectic polysaccharide in food and other products containing ascorbic acid.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹

Article Chemistry, Applied

Protective effect of antioxidant peptides from grass carp scale gelatin on the H2O2-mediated oxidative injured HepG2 cells

Yue-ming Hu et al.

Summary: The antioxidant peptides from grass carp scale gelatin have a protective effect on H2O2-mediated oxidative injured HepG2 cells, which could be attributed to the increase in SOD, CAT, and GPX activities, decrease in ROS level and MDA content, as well as reduced damage on cell membrane and DNA. The peptide sequences of grass carp scale gelatin hydrolysates were mainly low molecular weight peptides, and the synergistic effect among them contributed to the strong antioxidant activities.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Food Science & Technology

Combined RNA-seq and molecular biology technology revealed the protective effect of Cyclocarya paliurus polysaccharide on H2O2-induced oxidative damage in L02 cells thought regulating mitochondrial function, oxidative stress and PI3K/Akt and MAPK signaling pathways

Xianxiang Chen et al.

Summary: The study found that Cyclocarya paliurus polysaccharide (CP) can protect L02 cells by regulating oxidative and mitochondrion related signal pathways, restoring normal cell function and increasing the expression of antioxidant enzymes. This suggests that CP may have potential as a therapeutic strategy for chronic diseases involving oxidative damage.

FOOD RESEARCH INTERNATIONAL (2022)

添加到收藏夹

Article Food Science & Technology

Antioxidant and hypolipidemic activities of pectin isolated from citrus canning processing water

Miao-Miao Wang et al.

Summary: This study investigated the antioxidant and hypolipidemic activities of pectin extracted from citrus fruit canning processing water. The pectins showed significant ability to scavenge free radicals and bind bile acids, effectively reducing oxidative stress and blood lipid levels. Furthermore, they down-regulated the expression of relevant genes associated with lipid metabolism. Therefore, these citrus pectins have potential as ingredients for functional foods.

LWT-FOOD SCIENCE AND TECHNOLOGY (2022)

添加到收藏夹

Article Chemistry, Applied

Metabolomics and biochemical insights on the regulation of aging-related diabetes by a low-molecular-weight polysaccharide from green microalga Chlorella pyrenoidosa

Yinghui Qiu et al.

Summary: The study found that Chlorella pyrenoidosa polysaccharide (CPP) has antioxidant and hypoglycemic effects in an aging-related diabetic (AD) mice model. It promotes tissue repair and reduces oxidative stress by activating the glucagon-like peptide-1 receptor/FOXO-1 pathway while inhibiting the interleukin-6 receptor/FOXO-1 pathway.

FOOD CHEMISTRY-X (2022)

添加到收藏夹

Article Chemistry, Applied

Structural characterization and hypolipidemic activity of Gracilaria lemaneiformis polysaccharide and its degradation products

Xiaoshan Long et al.

Summary: The research focused on analyzing the structural characteristics and hypolipidemic activity in vitro of G. lemaneiformis polysaccharide (GLP) and its degradation products. The results showed changes in chemical composition, particle size, and color brightness of GLP after degradation by H2O2-Vc, while thermal stability remained unaffected. Additionally, polysaccharide degradation led to significant differences in structure and activity.

FOOD CHEMISTRY-X (2022)

添加到收藏夹

Article Food Science & Technology

RNA-seq based elucidation of mechanism underlying Mesona chinensis Benth polysaccharide protected H2O2-induced oxidative damage in L02 cells

Xianxiang Chen et al.

Summary: This study found that Mesona chinensis Benth polysaccharides can protect cells from H2O2-induced oxidative damage by regulating mitochondrial function, affecting PI3K and MAPK signaling pathways. This protective effect is mainly achieved by improving mitochondrial membrane potential and increasing ATP synthesis.

FOOD RESEARCH INTERNATIONAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Construction of chitosan-based asymmetric antioxidant and anti-inflammatory repair film for acceleration of wound healing

Le Hu et al.

Summary: A novel chitosan-based asymmetric wound repair composite (BAWRC) film has been developed, which consists of two functional layers with antioxidant and antibacterial properties. The film showed excellent biocompatibility and promoted wound healing while preventing infection.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

添加到收藏夹

Review Chemistry, Medicinal

Seaweed Phenolics as Natural Antioxidants, Aquafeed Additives, Veterinary Treatments and Cross-Linkers for Microencapsulation

Tharuka Gunathilake et al.

Summary: Driven by consumer demand and government policies, the use of synthetic additives in aquafeed needs to be replaced with sustainable and natural alternatives. Seaweeds, as a sustainable marine source, contain bioactive phenolic compounds that can be used in various applications such as food, animal feed, aqua feeds, or microencapsulation. Seaweed phenolics, specifically phlorotannins found in brown seaweed, have unique structures and multiple antioxidant mechanisms. They can bind to proteins through covalent and non-covalent bonds, exhibiting specific bioactivities. Additionally, they can enhance the rheological and mechanical properties of food-grade delivery systems, showing the versatility of seaweed phenolics.

MARINE DRUGS (2022)

添加到收藏夹

Article Chemistry, Medicinal

Sulfated Polysaccharide Extracted from the Green Algae Codium bernabei: Physicochemical Characterization and Antioxidant, Anticoagulant and Antitumor Activity

Fabian A. Figueroa et al.

Summary: This study aims to isolate and characterize the polysaccharide fractions from Codium bernabei, a green alga found on Chilean coasts. The extracted fractions were mainly composed of sulfated galactan unit and exhibited antioxidant, anticoagulant, and antitumor activities. The findings suggest the potential biotechnological application of sulfated galactan polysaccharides from Chilean marine resources.

MARINE DRUGS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Maqui (Aristotelia chilensis (Mol.) Stuntz): A Natural Antioxidant to Improve Quality of Meat Patties

Lidiana Velazquez et al.

Summary: This study investigates the effect of Aristotelia chilensis leaf powders on the quality and shelf life of beef patties. The results show that the addition of maqui leaf powders can effectively delay the oxidation process and improve the quality of beef patties.

ANTIOXIDANTS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Loss of KEAP1 Causes an Accumulation of Nondegradative Organelles

Elisabet Uribe-Carretero et al.

Summary: KEAP1 is an adaptor protein that plays an important role in regulating protein degradation. Loss of KEAP1 leads to protein oxidative aggregation and defective autophagy. Our study demonstrates that KEAP1 deficiency affects the endosome-lysosomal pathway, resulting in downregulation of cathepsin D and accumulation of autophagosomes.

ANTIOXIDANTS (2022)

添加到收藏夹

Article Neurosciences

Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-?/NF-?B pathway

Hongyan Yao et al.

Summary: Fraxin could significantly ameliorate cerebral ischemia-reperfusion (I/R) injury by repressing oxidative stress, inflammatory response, and cell apoptosis through abrogating the PPAR gamma/ NF-kappa B pathway.

BRAIN RESEARCH BULLETIN (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Synthesis, characterization, in vitro antioxidant and hypoglycemic activities of selenium nanoparticles decorated with polysaccharides of Gracilaria lemaneiformis

Li Tang et al.

Summary: In this study, stable selenium nanoparticles were successfully prepared using Gracilaria lemaneiformis polysaccharides as stabilizer and dispersing agent. The nanoparticles showed good storage stability and high antioxidant capacity under different conditions, indicating their potential application as antioxidant and antidiabetic agents in food and medical fields.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Food Science & Technology

The possible mechanism of the protective effect of a sulfated polysaccharide from Gracilaria Lemaneiformis against colitis induced by dextran sulfate sodium in mice

Rui Han et al.

Summary: The study found that sulfated polysaccharide from Gracilaria Lemaneiformis could alleviate DSS-induced colitis by reducing inflammation, enhancing intestinal barrier, activating short chain fatty acid receptors, and regulating gut microbiota.

FOOD AND CHEMICAL TOXICOLOGY (2021)

添加到收藏夹

Article Chemistry, Applied

Structural characterization, functional properties and antioxidant activities of polysaccharide extract obtained from okra leaves (Abelmoschus esculentus)

Ibukunoluwa Fola Olawuyi et al.

Summary: This study characterized a water-soluble polysaccharide isolated from okra leaves, revealing its potential as a new polysaccharide source with comparable or superior functional properties, including thermal stability, emulsifying capacity, and antioxidant activity, compared to polysaccharides previously obtained from okra pods.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Food Science & Technology

Chlorogenic acid supplementation alleviates dextran sulfate sodium (DSS)-induced colitis via inhibiting inflammatory responses and oxidative stress, improving gut barrier integrity and Nrf-2/HO-1 pathway

Fan Wan et al.

Summary: Chlorogenic acid supplementation can effectively ameliorate DSS-induced colitis by activating the Nrf-2/HO-1 pathway to suppress oxidative stress and inflammatory responses, and promoting gut barrier.

JOURNAL OF FUNCTIONAL FOODS (2021)

添加到收藏夹

Article Food Science & Technology

Mulberry leaf phenolics and fiber exert anti-obesity through the gut microbiota-host metabolism pathway

Sentai Liao et al.

Summary: This study investigated the effects of mulberry leaf powder and components on preventing obesity and regulating lipid metabolism. The results showed that the fiber and phenolics of mulberry leaf have the potential for development of weight-loss functional foods.

JOURNAL OF FOOD SCIENCE (2021)

添加到收藏夹

Article Chemistry, Applied

Insights on preparation, structure and activities of Gracilaria lemaneiformis polysaccharide

Xiaoshan Long et al.

Summary: Gracilaria lemaneiformis polysaccharide (GLP) is a type of red algae rich in nutrients and functional components, with reported physiological activities such as regulating glycolipid metabolism, immune response, anti-tumor effects, and anti-inflammatory properties. This article summarizes the extraction, purification, structural characteristics, and physiological activities of GLP, providing a theoretical basis for future research and development.

FOOD CHEMISTRY-X (2021)

添加到收藏夹

Article Food Science & Technology

Structural characteristics and anti-inflammatory activity of UV/H2O2-treated algal sulfated polysaccharide from Gracilaria lemaneiformis

Yufeng Gong et al.

Summary: UV/H2O2 treatment significantly reduced the molecular weight and particle size of GLP, decreased the content of total sugars, uronic acids and proteins, and modified its surface morphology, showing the potential to enhance the anti-inflammatory activity of algal sulfated polysaccharides.

FOOD AND CHEMICAL TOXICOLOGY (2021)

添加到收藏夹

Article Food Science & Technology

Influence of UV/H2O2 treatment on polysaccharides from Sargassum fusiforme: Physicochemical properties and RAW 264.7 cells responses

Xiaoyong Chen et al.

Summary: UV/H2O2 treatment can improve the physicochemical properties of Sargassum fusiforme polysaccharides, reduce their toxicity in cells, and enhance their anti-inflammatory activity.

FOOD AND CHEMICAL TOXICOLOGY (2021)

添加到收藏夹

Article Food Science & Technology

Purification, characterization and biological activities of exopolysaccharides from Lactobacillus rhamnosus ZFM231 isolated from milk

Shu-Min Hu et al.

Summary: Exopolysaccharides (EPS) produced by Lactobacillus rhamnosus ZFM231 isolated from milk were purified and separated into four fractions, showing antioxidant and hypolipidemic activities, with potential applications in the food and pharmaceutical industries.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

添加到收藏夹

Article Food Science & Technology

Enrichment of dimerumic acid in Monascus-fermented rice and its in vivo antioxidant activity

Washim Khan et al.

Summary: Monascus-fermented rice (MFR) is used in traditional Chinese and Japanese medicine for various health issues. This study focused on screening out the medium composition for producing dimerumic acid (DMA) in MFR, with promising results in antioxidant potential. Solid-state fermentation of long-grain rice by specific strains of Monascus showed the highest yield of DMA, making it a potential source for natural antioxidants.

FOOD FRONTIERS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Optimization of Jiuzao protein hydrolysis conditions and antioxidant activity in vivo of Jiuzao tetrapeptide Asp-Arg-Glu-Leu by elevating the Nrf2/Keap1-p38/PI3K-MafK signaling pathway

Yunsong Jiang et al.

Summary: The study optimized the hydrolysis method of Jiuzao protein by using different proteinases, with pepsin exhibiting the highest hydrolysis degree. The antioxidant capacity of DREL in vivo was verified, and it was also found to activate the Nrf2/Keap1-p38/PI3K-MafK signaling pathway to improve antioxidant ability. Furthermore, DREL exhibited anti-inflammatory activity by inhibiting the secretion of inflammatory cytokines through Nrf2 activation.

FOOD & FUNCTION (2021)

添加到收藏夹

Article Chemistry, Applied

Sulfated oligosaccharide of Gracilaria lemaneiformis protect against food allergic response in mice by up-regulating immunosuppression

Qingmei Liu et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Chemistry, Physical

Viscosity study of tert-butyl alcohol aqueous solution by Brownian motion and gravimetric capillaries

Kazuki Furukawa et al.

JOURNAL OF MOLECULAR LIQUIDS (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Tailoring Cu substituted hydroxyapatite/functionalized multiwalled carbon nanotube composite coating on 316L SS implant for enhanced corrosion resistance, antibacterial and bioactive properties

Durairaj Sivaraj et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

添加到收藏夹

Correction Medicine, Research & Experimental

Thyroxine modulation of immune toxicity induced by mixture pesticides mancozeb and fipronil in mice (vol 240, 117078, 2020)

Farhad Bano et al.

LIFE SCIENCES (2020)

添加到收藏夹

Article Plant Sciences

Herbal decoction Divya-Swasari-Kwath attenuates airway inflammation and remodeling through Nrf-2 mediated antioxidant lung defence in mouse model of allergic asthma

Acharya Balkrishna et al.

PHYTOMEDICINE (2020)

添加到收藏夹

Article Chemistry, Applied

Chemical structure and snake antivenom properties of sulfated agarans obtained from Laurencia dendroidea (Ceramiales, Rhodophyta)

Luciana G. Ferreira et al.

CARBOHYDRATE POLYMERS (2019)

添加到收藏夹

Article Chemistry, Applied

Microwave assisted hydrothermal extraction of polysaccharides from Ulva prolifera: Functional properties and bioactivities

Yuan Yuan et al.

CARBOHYDRATE POLYMERS (2018)

添加到收藏夹

Article Chemistry, Applied

A novel antioxidant peptide, purified from Bacillus amyloliquefaciens, showed strong antioxidant potential via Nrf-2 mediated heme oxygenase-1 expression

Md. Saifur Rahman et al.

FOOD CHEMISTRY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Enhanced antimicrobial activity of naturally derived bioactive molecule chitosan conjugated silver nanoparticle against dental implant pathogens

Darshan Devang Divakar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

添加到收藏夹

Article Food Science & Technology

Effects of tetramethylpyrazine from Chinese black vinegar on antioxidant and hypolipidemia activities in HepG2 cells

Jicheng Chen et al.

FOOD AND CHEMICAL TOXICOLOGY (2017)

添加到收藏夹

Article Food Science & Technology

Antioxidant and immunostimulating activities in vitro of sulfated polysaccharides isolated from Gracilaria rubra

Tong Di et al.

JOURNAL OF FUNCTIONAL FOODS (2017)

添加到收藏夹

Article Food Science & Technology

Structural characterization and macrophage immunomodulatory activity of a polysaccharide isolated from Gracilaria lemaneiformis

Yinglang Ren et al.

JOURNAL OF FUNCTIONAL FOODS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Advantages of the polysaccharides from Gracilaria lemaneiformis over metformin in antidiabetic effects on streptozotocin-induced diabetic mice

Lingrong Wen et al.

RSC ADVANCES (2017)

添加到收藏夹

Article Chemistry, Applied

Dieckol enhances the expression of antioxidant and detoxifying enzymes by the activation of Nrf2-MAPK signalling pathway in HepG2 cells

Min-Sup Lee et al.

FOOD CHEMISTRY (2015)

添加到收藏夹

Article Food Science & Technology

Effects of natural (grape seed and chestnut extract) and synthetic antioxidants (buthylatedhydroxytoluene, BHT) on the physical, chemical, microbiological and sensory characteristics of dry cured sausage chorizo

Jose M. Lorenzo et al.

FOOD RESEARCH INTERNATIONAL (2013)

添加到收藏夹

Article Cell Biology

A comparative assessment of fluo Ca2+ indicators in rat ventricular myocytes

Brian M. Hagen et al.

CELL CALCIUM (2012)

添加到收藏夹

Article Chemistry, Analytical

Metal-enhanced fluorescence based calcium detection: Greater than 100-fold increase in signal/noise using Fluo-3 or Fluo-4 and silver nanostructures

Nina Bondre et al.

SENSORS AND ACTUATORS B-CHEMICAL (2011)

添加到收藏夹

Article Medicine, Research & Experimental

Possible use of quercetin, an antioxidant, for protection of cells suffering from overload of intracellular Ca2+:: A model experiment

Yoko Sakanashi et al.

LIFE SCIENCES (2008)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.