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CURRENT RESEARCH IN FOOD SCIENCE (2021)
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CARCINOGENESIS (2020)
Flavonoids as Anticancer Agents
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NUTRIENTS (2020)
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NUTRIENTS (2020)
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CELLS (2020)
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CELLS (2020)
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CELLS (2020)
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FRONTIERS IN PHYSIOLOGY (2020)
Alpinetin inhibits breast cancer growth by ROS/NF-κB/HIF-1α axis
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells
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BMC CANCER (2020)
TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1
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SCIENTIFIC REPORTS (2020)
Epigenetic regulation of matrix metalloproteinases in inflammatory diseases: a narrative review
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CELL AND BIOSCIENCE (2020)
CircFNDC3B sequestrates miR-937-5p to derepress TIMP3 and inhibit colorectal cancer progression
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MOLECULAR ONCOLOGY (2020)
Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases
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BIOMOLECULES (2020)
The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Flavonoids Regulate Inflammation and Oxidative Stress in Cancer
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MOLECULES (2020)
Important Flavonoids and Their Role as a Therapeutic Agent
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MOLECULES (2020)
The Power of Phytochemicals Combination in Cancer Chemoprevention
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JOURNAL OF CANCER (2020)
Molecular principles of metastasis: a hallmark of cancer revisited
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SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Luteolin, a flavonoid, as an anticancer agent: A review
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BIOMEDICINE & PHARMACOTHERAPY (2019)
Matrix metalloproteinases participation in the metastatic process and their diagnostic and therapeutic applications in cancer
Georgina Gonzalez-Avila et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2019)
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TRENDS IN CELL BIOLOGY (2019)
Quercetin suppresses the proliferation and metastasis of metastatic osteosarcoma cells by inhibiting parathyroid hormone receptor 1
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BIOMEDICINE & PHARMACOTHERAPY (2019)
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BIOMOLECULES (2019)
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CANCER MEDICINE (2019)
Matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor 2 (TIMP-2) in pancreatic cancer (PC)
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Oncotarget (2019)
Role of Matrix Metalloproteinases in Angiogenesis and Cancer
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FRONTIERS IN ONCOLOGY (2019)
Luteolin inhibits proliferation and induces apoptosis of human melanoma cells in vivo and in vitro by suppressing MMP-2 and MMP-9 through the PI3K/AKT pathway
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FOOD & FUNCTION (2019)
Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
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BMC CANCER (2018)
Effects of anthocyanins on the prevention and treatment of cancer
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BRITISH JOURNAL OF PHARMACOLOGY (2017)
Flavonoids and platelet aggregation: A brief review
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EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution
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JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Luteolin reduces migration of human glioblastoma cell lines via inhibition of the p-IGF-1R/PI3K/AKT/mTOR signaling pathway
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ONCOLOGY LETTERS (2017)
Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits
Hock Eng Khoo et al.
FOOD & NUTRITION RESEARCH (2017)
TIMPs: versatile extracellular regulators in cancer
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NATURE REVIEWS CANCER (2017)
Chalcone: A Privileged Structure in Medicinal Chemistry
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CHEMICAL REVIEWS (2017)
Baicalein Inhibits the Migration and Invasion of B16F10 Mouse Melanoma Cells through Inactivation of the PI3K/Akt Signaling Pathway
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BIOMOLECULES & THERAPEUTICS (2017)
Hypothesis: Metalloproteinase Inhibitors Decrease Risks of Cardiovascular Disease
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JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2016)
Tissue inhibitor of metalloproteinases-4 (TIMP-4) regulates stemness in cervical cancer cells
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MOLECULAR CARCINOGENESIS (2016)
Naringin inhibits the invasion and migration of human glioblastoma cell via downregulation of MMP-2 and MMP-9 expression and inactivation of p38 signaling pathway
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TUMOR BIOLOGY (2016)
Kaempferol inhibits the growth and metastasis of cholangiocarcinoma in vitro and in vivo
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ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2016)
Clinical Use of the Urine Biomarker [TIMP-2] x [ IGFBP7] for Acute Kidney Injury Risk Assessment
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AMERICAN JOURNAL OF KIDNEY DISEASES (2016)
Tangeretin induces cell cycle arrest and apoptosis through upregulation of PTEN expression in glioma cells
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BIOMEDICINE & PHARMACOTHERAPY (2016)
TIMP-1 expression induced by IL-32 is mediated through activation of AP-1 signal pathway
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INTERNATIONAL IMMUNOPHARMACOLOGY (2016)
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JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2016)
TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway
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JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Inhibitory effect of quercetin on colorectal lung metastasis through inducing apoptosis, and suppression of metastatic ability
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PHYTOMEDICINE (2016)
TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: A potential novel approach to the treatment of metastatic colorectal cancer
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ONCOTARGET (2016)
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JOURNAL OF NUTRITIONAL SCIENCE (2016)
Tissue inhibitor of metalloproteinase-3 (TIMP3) promotes endothelial apoptosis via a caspase-independent mechanism
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APOPTOSIS (2015)
The role of TIMPs in regulation of extracellular matrix proteolysis
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MATRIX BIOLOGY (2015)
TGF-β1 and TIMP-4 regulate atrial fibrosis in atrial fibrillation secondary to rheumatic heart disease
Yu Sun et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
Evaluation of MMP-2, MMP-9, TIMP-1, TIMP-2, NGAL and MMP-9/NGAL complex in urine and sera from patients with bladder cancer
Serena Ricci et al.
ONCOLOGY LETTERS (2015)
TIMP-1 activated carcinoma-associated fibroblasts inhibit tumor apoptosis by activating SDF1/CXCR4 signaling in hepatocellular carcinoma
Tao Song et al.
ONCOTARGET (2015)
Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes
H. Cui et al.
ONCOGENE (2015)
TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis
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PLOS ONE (2015)
Luteolin inhibits matrix metalloproteinase 9 and 2 in azoxymethane-induced colon carcinogenesis
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HUMAN & EXPERIMENTAL TOXICOLOGY (2014)
Tangeretin, a citrus pentamethoxyflavone, exerts cytostatic effect via p53/p21 up-regulation and suppresses metastasis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinoma
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JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)
TIMP-1 via TWIST1 Induces EMT Phenotypes in Human Breast Epithelial Cells
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MOLECULAR CANCER RESEARCH (2014)
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NATURE REVIEWS DRUG DISCOVERY (2014)
Functional Characterization of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) N- and C-Terminal Domains during Xenopus laevis Development
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SCIENTIFIC WORLD JOURNAL (2014)
Antimetastatic effects of licochalcone A on oral cancer via regulating metastasis-associated proteases
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TUMOR BIOLOGY (2014)
MMP-2, MMP-3, TIMP-1, TIMP-2, and TIMP-3 Protein Levels in Human Aqueous Humor: Relationship With Axial Length
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)
Natural products as potential cancer therapy enhancers: A preclinical update
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SAGE OPEN MEDICINE (2014)
Flavonoids from Orostachys japonicus A. Berger Inhibit the Invasion of LnCaP Prostate Carcinoma Cells by Inactivating Akt and Modulating Tight Junctions
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3β/NF-κB signaling cascade
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MOLECULAR NUTRITION & FOOD RESEARCH (2013)
Total Flavonoids of Scutellaria barbata Inhibit Invasion of Hepatocarcinoma via MMP/TIMP in Vitro
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MOLECULES (2013)
TGF-β-Elicited Induction of Tissue Inhibitor of Metalloproteinases (TIMP)-3 Expression in Fibroblasts Involves Complex Interplay between Smad3, p38α, and ERK1/2
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PLOS ONE (2013)
Cell Surface-Bound TIMP3 Induces Apoptosis in Mesenchymal Cal78 Cells through Ligand-Independent Activation of Death Receptor Signaling and Blockade of Survival Pathways
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PLOS ONE (2013)
Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes
Jyotica Batra et al.
PLOS ONE (2013)
Kaempferol Reduces Matrix Metalloproteinase-2 Expression by Down-Regulating ERK1/2 and the Activator Protein-1 Signaling Pathways in Oral Cancer Cells
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PLOS ONE (2013)
TIMP-1 Promotes Accumulation of Cancer Associated Fibroblasts and Cancer Progression
Yixuan Gong et al.
PLOS ONE (2013)
Chemistry and Biological Activities of Flavonoids: An Overview
Shashank Kumar et al.
SCIENTIFIC WORLD JOURNAL (2013)
ERK2-regulated TIMP1 Induces Hyperproliferation of K-RasG12D- Transformed Pancreatic Ductal Cells
Gregory P. Botta et al.
NEOPLASIA (2013)
Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling
Rong-Rui Liang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo
Elong Lin et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)
Endogenous Angiogenesis Inhibitor Blocks Tumor Growth via Direct and Indirect Effects on Tumor Microenvironment
Dimitra Bourboulia et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Physiology and pathophysiology of matrix metalloproteases
T. Klein et al.
AMINO ACIDS (2011)
Plasma TIMP-1 levels and treatment outcome in patients treated with XELOX for metastatic colorectal cancer
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ANNALS OF ONCOLOGY (2011)
Biological role of matrix metalloproteinases: a critical balance
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EUROPEAN RESPIRATORY JOURNAL (2011)
Dietary chalcones with chemopreventive and chemotherapeutic potential
Barbora Orlikova et al.
GENES AND NUTRITION (2011)
TIMP-3 promotes apoptosis in nonadherent small cell lung carcinoma cells lacking functional death receptor pathway
Janne P. Kallio et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Inhibitory Activity of Flavonoids against Class I Phosphatidylinositol 3-Kinase Isoforms
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MOLECULES (2011)
Extracellular Matrix Degradation and Remodeling in Development and Disease
Pengfei Lu et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
Novel targets for Spinal Cord Injury related neuropathic pain
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ANNALS OF NEUROSCIENCES (2011)
The diagnostic value of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of matrix metalloproteinases 1 (TIMP-1) determination in the sera of colorectal adenoma and cancer patients
Barbara Mroczko et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2010)
A Brief Review on the Mechanisms of miRNA Regulation
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GENOMICS PROTEOMICS & BIOINFORMATICS (2010)
Tissue Inhibitor of Metalloproteinase-4 Is Elevated in Early-Stage Breast Cancers with Accelerated Progression and Poor Clinical Course
Michaelann Liss et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
MicroRNAs in Cancer
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ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2009)
Effects of Panduratin A Isolated from Kaempferia pandurata ROXB. on the Expression of Matrix Metalloproteinase-9 by Porphyromonas gingivalis Supernatant-Induced KB Cells
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BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)
Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling
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JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2009)
Increased expression of matrix metalloproteinases-21 and-26 and TIMP-4 in pancreatic adenocarcinoma
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MODERN PATHOLOGY (2007)
Prognostic significance of matrix metalloproteinases-1,-2,-7 and-13 and tissue inhibitors of metalloproteinases-1,-2,-3 and-4 in colorectal cancer
Marja Hilska et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
A novel mechanism of tissue inhibitor of metalloproteinases-1 activation by interleukin-1 in primary human astrocytes
Katarzyna M. Wilczynska et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118
J. Oh et al.
ONCOGENE (2006)
TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27KIP1 protein
M. E. Taube et al.
ONCOGENE (2006)
Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line
Pei-Ni Chen et al.
CANCER LETTERS (2006)
Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells
DW Seo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium):: possible roles for protein kinase C and mitogen-activated protein-kinase-mediated events
MD Matchett et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2006)
Tissue inhibitor of metalloproteinases-4 suppresses vascular smooth muscle cell migration and induces cell apoptosis
YH Guo et al.
LIFE SCIENCES (2004)
Flavonoids inhibit VEGF/VGF-induced angiogenesis in vitro by inhibiting the matrix-degrading proteases
MH Kim
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Matrix metalloproteinases and tissue inhibitors of metalloproteinases - Structure, function, and biochemistry
R Visse et al.
CIRCULATION RESEARCH (2003)
Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors
M Ahonen et al.
ONCOGENE (2003)
Complex roles of tissue inhibitors of metalloproteinases in cancer
YF Jiang et al.
ONCOGENE (2002)
The human tissue inhibitor of metalloproteinases (TIMP)-1 gene contains repressive elements within the promoter and intron 1
G Dean et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)