4.2 Review

A Review on Traditional Anti-ulcer Medicinal Plants

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Article Biochemistry & Molecular Biology

Antiulcer activity of proanthocyanidins is mediated via suppression of oxidative, inflammatory, and apoptotic machineries

Maha S. Lokman et al.

Summary: This study investigated the potential therapeutic role of proanthocyanidins (PAs) against acidified ethanol-induced gastric ulcer in rats. PAs pretreatment significantly reduced pathological changes in the gastric mucosa and activated natural antioxidant molecules while attenuating pro-oxidant formation. Additionally, high-dose PAs supplementation suppressed gastric inflammatory and apoptotic responses.

JOURNAL OF FOOD BIOCHEMISTRY (2022)

Article Biochemistry & Molecular Biology

Russelioside B; A pregnane glycoside for treatment of gastric ulcer via modulation of heat shock protein-70 and vascular endothelial growth factor

Riham A. El-Shiekh et al.

Summary: Russelioside B showed gastroprotective action through multi mechanistic actions, including suppression of gastric oxidative stress, inflammation, anti-apoptotic activities, and enhanced gastric mucosal protection by up-regulation of endothelial growth factor, normalization of heat shock protein-70, and prostaglandin E2. These actions were comparable to some classical antiulcer drugs such as Antodine.

STEROIDS (2021)

Article Biochemistry & Molecular Biology

Gastroprotective Activities of Ethanol Extract of Black Rice Bran (Oryza sativa L.) in Rats

Peerachit Tonchaiyaphum et al.

Summary: This study evaluated the gastroprotective activities of black rice bran ethanol extract (BRB) from the Thai black rice variety Hom Nil and found that its mechanism of action may be through antioxidant activity. BRB inhibited ulcer formation in gastric ulcer models, but did not affect gastric wall mucus or acidity. However, it could normalize tissue MDA levels through radical scavenging activity.

MOLECULES (2021)

Review Medicine, Research & Experimental

Pharmacological insights into antioxidants against colorectal cancer: A detailed review of the possible mechanisms

Sivapragasam Gothai et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Gastroenterology & Hepatology

Perforated peptic ulcer - an update

Kin Tong Chung et al.

WORLD JOURNAL OF GASTROINTESTINAL SURGERY (2017)

Article Pharmacology & Pharmacy

Separation and identification of phenolic acid and flavonoids from Nerium indicum flowers

A. Vinayagam et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)

Article Pharmacology & Pharmacy

Comparative antidiarrheal and antiulcer effect of the aqueous and ethanolic stem bark extracts of Tinospora cordifolia in rats

Mohanjit Kaur et al.

JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH (2014)

Article Integrative & Complementary Medicine

Assessment of the Antiulcer Potential of Moringa oleifera Root-Bark Extract in Rats

Manoj Kumar Choudhary et al.

JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES (2013)

Article Pharmacology & Pharmacy

Analgesic and Anti-Ulcer Activities of Ethanol and Aqueous Extracts of Root of Bauhinia variegata Linn.

Yamini R. Kumar et al.

INTERNATIONAL JOURNAL OF PHARMACOLOGY (2011)

Article Plant Sciences

Antiulcerogenic activity of Terminalia chebula fruit in experimentally induced ulcer in rats

Praveen Sharma et al.

PHARMACEUTICAL BIOLOGY (2011)

Article Pharmacology & Pharmacy

Antiulcer effect of the methanolic extract of Tamarindus indica seeds in different experimental models

Pankaj Kalra et al.

JOURNAL OF PHARMACY AND BIOALLIED SCIENCES (2011)

Article Public, Environmental & Occupational Health

Study of anti ulcer activity of Ficus religiosa L. on experimentally induced gastric ulcers in rats

Sarmistha Saha et al.

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE (2010)

Article Plant Sciences

Antiulcer activity of methanolic extract of Momordica charantia L. in rats

Samsul Alam et al.

JOURNAL OF ETHNOPHARMACOLOGY (2009)

Review Medicine, General & Internal

Peptic ulcer disease

Peter Malfertheiner et al.

LANCET (2009)

Article Pharmacology & Pharmacy

Evalution of anti-ulcer activity of Polyalthia longifolia (Sonn.) Thwaites in experimental animals

P. Malairajan et al.

INDIAN JOURNAL OF PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Extraction of glycyrrhizic acid and glabridin from licorice

Minglei Tian et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2008)

Article Agriculture, Multidisciplinary

Chemical composition and antioxidant property of holy basil (Ocimum sanctum L.) leaves, stems, and inflorescence and their in vitro callus cultures

F. Lukmanul Hakkim et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)

Article Plant Sciences

Antiulcer and in vitro antioxidant activities of Jasminum grandiflorum L.

M. Umamaheswari et al.

JOURNAL OF ETHNOPHARMACOLOGY (2007)

Review Plant Sciences

Pharmacological actions and potential uses of Momordica charantia:: a review

JK Grover et al.

JOURNAL OF ETHNOPHARMACOLOGY (2004)