☆ 4.7 Article

Bovine hemoglobin thermal stability in the presence of naringenin: Calorimetric, spectroscopic and molecular modeling studies

JOURNAL OF MOLECULAR LIQUIDS (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Medicine, Research & Experimental

Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms

Hasan Slika et al.

Summary: Cancer is a major cause of global morbidity and mortality. Flavonoids are natural polyphenols with established anticancer and antioxidant capacities. They can inhibit carcinogenesis by suppressing reactive oxygen species (ROS), but also induce cancer cell death through excessive oxidative stress. This review explores the antioxidant capacity and pro-oxidant roles of flavonoids, as well as their pathways in cancer prevention and treatment. The review also emphasizes the anticancer functions of specific flavonoids in various cancers and their structure-function relations.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Environmental factors modulating protein conformations and their role in protein aggregation diseases

Shweta Devi et al.

Summary: Physiological conditions and environmental risk factors play significant roles in influencing protein structure and disease development.

TOXICOLOGY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Role of polyphenols in combating Type 2 Diabetes and insulin resistance

Moyad Shahwan et al.

Summary: Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic disorder of non-insulin-dependent diabetes mellitus. Polyphenolic compounds play an important role in regulating insulin resistance and carbohydrate metabolism through inhibiting key enzymes and activating specific pathways to control blood glucose levels.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

添加到收藏夹

Article Chemistry, Physical

Multispectroscopic and computational studies of interaction of bovine serum albumin, human serum albumin and bovine hemoglobin with bisacodyl

Afreen Banu et al.

Summary: This study investigated the interaction mechanism of the drug Bisacodyl with carrier proteins including Bovine Serum Albumin, Human Serum Albumin, and Bovine Hemoglobin, revealing static quenching mechanism and complex formation. The findings showed conformational changes in the proteins' structures and higher quenching effect on Tryptophan residue compared to Tyrosine residue. The spectroscopic studies were supported by computational analysis, indicating the formation of complexes.

JOURNAL OF MOLECULAR STRUCTURE (2022)

添加到收藏夹

Article Chemistry, Physical

Exploring binding mechanism of naringenin to human transferrin using combined spectroscopic and computational methods: Towards therapeutic targeting of neurodegenerative diseases

Shama Khan et al.

Summary: This study investigates the binding of naringenin (Nag) to human transferrin (hTf) using computational and experimental methods. The results demonstrate that Nag binds to hTf with a high affinity through metal coordination bonding without causing significant structural alterations to hTf. Fluorescence binding and isothermal titration calorimetry studies further confirm the binding nature and thermodynamic parameters of the hTf-Nag complex. These findings provide a potential strategy and platform to utilize Nag in the treatment of neurodegenerative disorders.

JOURNAL OF MOLECULAR LIQUIDS (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

The functional role of the hemoglobin-water interface

Markus Meuwly et al.

Summary: This article provides a summary of the physiological relevance of the interface between hemoglobin and its environment, with a focus on water. In vitro, in vivo, and computational experiments are summarized and discussed. The results suggest that the stability of the deoxy T-state can be affected by the hydrophobic effect, which has implications for protein stability under physiological conditions. Molecular simulations also provide insights into the Perutz model for Hb function. The challenges and potential future directions for computational studies in crowded environments are also briefly mentioned.

MOLECULAR ASPECTS OF MEDICINE (2022)

添加到收藏夹

Article Medicine, Research & Experimental

Puerariae Lobatae radix flavonoids and puerarin alleviate alcoholic liver injury in zebrafish by regulating alcohol and lipid metabolism

Yu-Shi Liu et al.

Summary: The study demonstrated that PLR flavonoids and puerarin can alleviate alcohol-induced hepatic steatosis in zebrafish larvae by regulating alcohol and lipid metabolism, which is closely related to the AMPKα-ACC signaling pathway.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Review Chemistry, Medicinal

Therapeutic Effects and Safe Uses of Plant-Derived Polyphenolic Compounds in Cardiovascular Diseases: A Review

Badriyah Shadid Alotaibi et al.

Summary: Polyphenols have been recognized for their health benefits, especially in cardiovascular diseases, due to their strong antioxidant activity. Recent studies have shown their potential in combating cardiovascular pathologies through various signaling pathways and receptors, demonstrating cardioprotective effects in both in vitro and clinical experiments.

DRUG DESIGN DEVELOPMENT AND THERAPY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight

Anas Shamsi et al.

Summary: Recent research emphasizes the significant role of metal dyshomeostasis in Alzheimer's disease, where iron homeostasis is crucial for normal brain function. Flavonoids like quercetin and naringenin are explored for their therapeutic potential in treating neurodegenerative disorders. Studying the binding of these polyphenols with ferritin is vital for understanding their therapeutic mechanisms in AD.

ACS OMEGA (2021)

添加到收藏夹

Article Biochemical Research Methods

Using lysozyme amyloid fibrils as a means of scavenging aggregation-inhibiting compounds

Mantas Ziaunys et al.

Summary: The aggregation of amyloidogenic proteins is related to various diseases, with limited treatment options currently available. The challenge in the discovery of potential anti-amyloid molecules lies in identifying the actual inhibitors from complex mixtures. This study successfully scavenged potential aggregation-inhibiting molecules from different compounds and effectively separated them from the aggregates.

BIOTECHNOLOGY JOURNAL (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structure-based investigation of MARK4 inhibitory potential of Naringenin for therapeutic management of cancer and neurodegenerative diseases

Saleha Anwar et al.

Summary: The study suggests that Naringenin (NAG) may be an effective inhibitor of MARK4, as indicated by molecular docking and MD simulation studies showing that NAG can stabilize the structure of MARK4 and has excellent binding affinity with an impressive IC50 value.

JOURNAL OF CELLULAR BIOCHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Physical

Calorimetric, spectroscopic and computational investigation of morin binding effect on bovine serum albumin stability

Aurica Precupas et al.

Summary: Morin was found to have two binding sites with bovine serum albumin and could increase the thermal stability of the protein. Molecular docking and dynamic simulations supported the binding receptors of Morin with BSA. The dual action of Morin was shown to stabilize the protein structure and promote aggregation.

JOURNAL OF MOLECULAR LIQUIDS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

EXPLORING THE INTERACTION OF 5,6-BENZOCOUMARIN-3-CARBOXYLIC ACID WITH BOVINE SERUM ALBUMIN AT THE MOLECULAR LEVEL: A BIOPHYSICAL INVESTIGATION USING MOLECULAR DYNAMICS

Aurica Precupas et al.

Summary: In this study, molecular dynamics was used to monitor the conformational space covered by a ligand in the binding pocket of a protein, with analysis focused on the formation of hydrogen bonds and the conformational evolution of the ligand.

REVUE ROUMAINE DE CHIMIE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

3D-QSAR, docking, molecular dynamics simulation and free energy calculation studies of some pyrimidine derivatives as novel JAK3 inhibitors

Anand Balupuri et al.

ARABIAN JOURNAL OF CHEMISTRY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Interaction of piroxicam with bovine serum albumin investigated by spectroscopic, calorimetric and computational molecular methods

Ludmila Aricov et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Exploring the interaction of bioactive kaempferol with serum albumin, lysozyme and hemoglobin: A biophysical investigation using multi-spectroscopic, docking and molecular dynamics simulation studies

Sourav Das et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Photophysical behavior of heme group: Unfolding of hemoglobin and myoglobin in the presence of Gemini surfactants of different molecular architectures

Lavanya Tandon et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Atomistic Simulations of Heme Dissociation Pathways in Human Methemoglobins Reveal Hidden Intermediates

Premila P. Samuel et al.

BIOCHEMISTRY (2020)

添加到收藏夹

Article Spectroscopy

The study on the interactions of two 1,2,3-triazoles with several biological macromolecules by multiple spectroscopic methodologies and molecular docking

Rongqiang Liu et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition

Saleha Anwar et al.

SCIENTIFIC REPORTS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Rosmarinic acid restrains protein glycation and aggregation in human serum albumin: Multi spectroscopic and microscopic insight - Possible Therapeutics Targeting Diseases

Anas Shamsi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Simulating Absorption Spectra of Flavonoids in Aqueous Solution: A Polarizable QM/MM Study

Sulejman Skoko et al.

MOLECULES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

The role of flavonoids in autoimmune diseases: Therapeutic updates

Kannan R. R. Rengasamy et al.

PHARMACOLOGY & THERAPEUTICS (2019)

添加到收藏夹

Article Spectroscopy

Probing the interaction between levamlodipine and hemoglobin based on spectroscopic and molecular docking methods

Linlin Xu et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol

Danja J. Den Hartogh et al.

BIOMOLECULES (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Gallic acid influence on bovine serum albumin thermal stability

Aurica Precupas et al.

NEW JOURNAL OF CHEMISTRY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Type I beta turns make a new twist in pentapeptide repeat proteins: Crystal structure of Alr5209 from Nostoc sp. PCC 7120 determined at 1.7 angstrom resolution

Ruojing Zhang et al.

JOURNAL OF STRUCTURAL BIOLOGY-X (2019)

添加到收藏夹

Review Chemistry, Medicinal

The Therapeutic Potential of Naringenin: A Review of Clinical Trials

Bahare Salehi et al.

PHARMACEUTICALS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Probing the interaction of anticancer drug temsirolimus with human serum albumin: molecular docking and spectroscopic insight

Anas Shamsi et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Carboxylic acids of different nature induces aggregation of hemoglobin

Samra Hasan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

CalFitter: a web server for analysis of protein thermal denaturation data

Stanislav Mazurenko et al.

NUCLEIC ACIDS RESEARCH (2018)

添加到收藏夹

Article Chemistry, Physical

Critical insight into the interaction of naringenin with human haemoglobin: A combined spectroscopic and computational modeling approaches

Subhajit Maity et al.

JOURNAL OF MOLECULAR STRUCTURE (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Complex interaction of caffeic acid with bovine serum albumin: calorimetric, spectroscopic and molecular docking evidence

Aurica Precupas et al.

NEW JOURNAL OF CHEMISTRY (2017)

添加到收藏夹

Article Biochemical Research Methods

Interaction Analysis of T7 RNA Polymerase with Heparin and Its Low Molecular Weight Derivatives - An In Silico Approach

Subhomoi Borkotoky et al.

BIOINFORMATICS AND BIOLOGY INSIGHTS (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

The thermal and storage stability of bovine haemoglobin by ultraviolet-visible and circular dichroism spectroscopies

Ruchir Bhomia et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2016)

添加到收藏夹

Article Biochemical Research Methods

Concomitant Raman spectroscopy and dynamic light scattering for characterization of therapeutic proteins at high concentrations

Chen Zhou et al.

ANALYTICAL BIOCHEMISTRY (2015)

添加到收藏夹

Article Chemistry, Medicinal

g_mmpbsa-A GROMACS Tool for High-Throughput MM-PBSA Calculations

Rashmi Kumari et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)

添加到收藏夹

Article Thermodynamics

Detection and characterization of hemoglobin dissociation and aggregation using microcalorimetry

YeongHo Suh et al.

JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY (2014)

添加到收藏夹

Article Chemistry, Physical

Exploring the capabilities of TDDFT calculations to explain the induced chirality upon a binding process: A simple case, 3-carboxycoumarin

Aurica Varlan et al.

JOURNAL OF MOLECULAR STRUCTURE (2013)

添加到收藏夹

Article Optics

A critical study on the interactions of hesperitin with human hemoglobin: Fluorescence spectroscopic and molecular modeling approach

Sandipan Chakraborty et al.

JOURNAL OF LUMINESCENCE (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Hemoglobin Interactions with αB Crystallin: A Direct Test of Sensitivity to Protein Instability

Tyler J. W. Clark et al.

PLOS ONE (2012)

添加到收藏夹

Article Biophysics

Definition and testing of the GROMOS force-field versions 54A7 and 54B7

Nathan Schmid et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2011)

添加到收藏夹

Article Agriculture, Multidisciplinary

Noncovalent Interaction of Dietary Polyphenols with Bovine Hemoglobin in Vitro: Molecular Structure/Property-Affinity Relationship Aspects

Jian Bo Xiao et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Antibacterial activity of naringin derivatives against pathogenic strains

G. Celiz et al.

JOURNAL OF APPLIED MICROBIOLOGY (2011)

添加到收藏夹

Article Chemistry, Physical

An Automated Force Field Topology Builder (ATB) and Repository: Version 1.0

Alpeshkumar K. Malde et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)

添加到收藏夹

Article Polymer Science

Denaturant-induced helix-coil transition of oligopeptides: theoretical and equilibrium studies of short oligopeptides C17 and AK16

Fumiaki Kano et al.

POLYMER JOURNAL (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

Distal Histidine Stabilizes Bound O2 and Acts as a Gate for Ligand Entry in Both Subunits of Adult Human Hemoglobin

Ivan Birukou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

添加到收藏夹

Review Biochemistry & Molecular Biology

The protein kingdom extended: Ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation

Konstantin K. Turoverov et al.

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2010)

添加到收藏夹

Article Chemistry, Medicinal

Studies on the interaction of caffeine with bovine hemoglobin

Yan-Qing Wang et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)

添加到收藏夹

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Thermal Response with Exothermic Effects of β2-Microglobulin Amyloid Fibrils and Fibrillation

Kenji Sasahara et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

添加到收藏夹

Article Physics, Fluids & Plasmas

Model for amorphous aggregation processes

Samuel D. Stranks et al.

PHYSICAL REVIEW E (2009)

添加到收藏夹

Article Biophysics

Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature

A. M. Stadler et al.

BIOPHYSICAL JOURNAL (2008)

添加到收藏夹

Article Biophysics

Molecular dynamics Simulations of hemoglobin a in different states and bound to DPG: Effector-linked perturbation of tertiary conformations and HbA concerted dynamics

Monique Laberge et al.

BIOPHYSICAL JOURNAL (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

Lee Whitmore et al.

BIOPOLYMERS (2008)

添加到收藏夹

Article Chemistry, Physical

Dynamical changes of hemoglobin and its surrounding water during thermal denaturation as studied by quasielastic neutron scattering and temperature modulated differential scanning calorimetry

H. Jansson et al.

JOURNAL OF CHEMICAL PHYSICS (2008)

添加到收藏夹

Article Hematology

Enhanced oxidative cross-linking of hemoglobin E with spectrin and loss of erythrocyte membrane asymmetry in hemoglobin Eβ-thalassemia

Poppy Datta et al.

BLOOD CELLS MOLECULES AND DISEASES (2006)

添加到收藏夹

Article Biochemistry & Molecular Biology

Solvent effects on the conformational transition of a model polyalanine peptide

HD Nguyen et al.

PROTEIN SCIENCE (2004)

添加到收藏夹

Article Biophysics

Protein thermal aggregation involves distinct regions: Sequential events in the heat-induced unfolding and aggregation of hemoglobin

YB Yan et al.

BIOPHYSICAL JOURNAL (2004)

添加到收藏夹

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

添加到收藏夹

Review Chemistry, Multidisciplinary

Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation

EY Chi et al.

PHARMACEUTICAL RESEARCH (2003)

添加到收藏夹

Article Biochemistry & Molecular Biology

Static and dynamic light scattering approach to the hydration of hemoglobin and its supertetramers in the presence of osmolites

D Arosio et al.

BIOPOLYMERS (2002)

添加到收藏夹

Article Multidisciplinary Sciences

Electrostatics of nanosystems: Application to microtubules and the ribosome

NA Baker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

添加到收藏夹

Article Biochemistry & Molecular Biology

Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin

TC Mueser et al.

BIOCHEMISTRY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.