4.5 Letter

Mosaicism for the smooth muscle cell (SMC)-specific knock-in of the Acta2 R179C pathogenic variant: Implications for gene editing therapies

期刊

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
卷 171, 期 -, 页码 102-104

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.yjmcc.2022.07.004

关键词

Acta2; Thoracic aortic aneurysms and dissections; Vascular smooth muscle cells; Gene therapy; Genetic mouse models

资金

  1. National Heart, Lung and Blood Institute [RO1 HL146583]
  2. America Heart Association Merit Award
  3. Olivia Petrera-Cohen Research Fund
  4. Marylin and Frederick R. Lummis, MD, Fellowship in the Biomedical Sciences
  5. NIH [TL1TR003169, UL1TR003167, F32HL154681, T32GM120011, R01AR066629]
  6. Marfan Foundation McKusick Fellowship Award
  7. AHA Postdoctoral Fellowship
  8. American Heart Association [20CDA35310689]

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