相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。P53 deficiency affects cholesterol esterification to exacerbate hepatocarcinogenesis
Yahui Zhu et al.
HEPATOLOGY (2023)
Too complex to fail? Targeting fatty acid metabolism for cancer therapy
Rimsha Munir et al.
PROGRESS IN LIPID RESEARCH (2022)
Metabolic modulation of immune checkpoints and novel therapeutic strategies in cancer
Yi Wang et al.
SEMINARS IN CANCER BIOLOGY (2022)
Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice
Yahui Zhu et al.
JCI INSIGHT (2022)
Acetyl-CoA synthetases ACSS1 and ACSS2 are 4-hydroxytamoxifen responsive factors that promote survival in tamoxifen treated and estrogen deprived cells
Sarah Calhoun et al.
TRANSLATIONAL ONCOLOGY (2022)
Targeting lipid metabolism in the treatment of ovarian cancer
Saliha Chaudhry et al.
Oncotarget (2022)
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth
Chunming Cheng et al.
NATURE METABOLISM (2022)
The IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis
Li Gu et al.
HEPATOLOGY (2021)
USP17-mediated de-ubiquitination and cancer: Clients cluster around the cell cycle
Charles Ducker et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2021)
ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells
Latika Singh et al.
MOLECULAR CANCER RESEARCH (2021)
Contradictory roles of lipid metabolism in immune response within the tumor microenvironment
Weina Yu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)
Cancer-associated fibroblasts: overview, progress, challenges, and directions
Qinrong Ping et al.
CANCER GENE THERAPY (2021)
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
Xingzhe Ma et al.
CELL METABOLISM (2021)
Human CD36hi monocytes induce Foxp3+ CD25+ T cells with regulatory functions from CD4 and CD8 subsets
Jessica G. Lee et al.
IMMUNOLOGY (2021)
Lipid signalling enforces functional specialization of Treg cells in tumours
Seon Ah Lim et al.
NATURE (2021)
Metabolism of Dendritic Cells in Tumor Microenvironment: For Immunotherapy
Xin Peng et al.
FRONTIERS IN IMMUNOLOGY (2021)
USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1
Yahui Zhu et al.
CELL REPORTS (2021)
T cell metabolism in homeostasis and cancer immunity
Jun Wei et al.
CURRENT OPINION IN BIOTECHNOLOGY (2021)
The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells
Edward V. Prochownik et al.
CELLS (2021)
Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis
Yahui Zhu et al.
MOLECULAR CELL (2020)
Reprogramming of fatty acid metabolism in cancer
Nikos Koundouros et al.
BRITISH JOURNAL OF CANCER (2020)
Enhanced Lipid Accumulation and Metabolism Are Required for the Differentiation and Activation of Tumor-Associated Macrophages
Pan Su et al.
CANCER RESEARCH (2020)
Post-translational modifications of protein in response to ionizing radiation
Xiaodong Liu et al.
CELL BIOCHEMISTRY AND FUNCTION (2020)
Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function
Cameron S. Field et al.
CELL METABOLISM (2020)
Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
Lin Liu et al.
DEVELOPMENTAL CELL (2020)
CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential
Isabel R. Schlaepfer et al.
ENDOCRINOLOGY (2020)
Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells
Alicia Bort et al.
MOLECULAR BIOLOGY REPORTS (2020)
CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
Haiyang Zhang et al.
MOLECULAR CANCER (2020)
Mechanisms and regulation of cholesterol homeostasis
Jie Luo et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis
Li Gu et al.
ONCOGENE (2020)
Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target
Olga A. Sukocheva et al.
PHARMACOLOGY & THERAPEUTICS (2020)
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis
Jiyu Zhou et al.
NATURE COMMUNICATIONS (2020)
Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells
Sicheng Fu et al.
NATURE COMMUNICATIONS (2020)
Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1
Caroline Imbert et al.
NATURE COMMUNICATIONS (2020)
TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells
Cyril Corbet et al.
NATURE COMMUNICATIONS (2020)
Non-Histone Arginine Methylation by Protein Arginine Methyltrans-ferases
Ayad A. Al-Hamashi et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2020)
Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells
Jin Gong et al.
CELL DEATH & DISEASE (2020)
MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer
Honglei Wu et al.
CELL DEATH & DISEASE (2020)
Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response
Natalia Trempolec et al.
CANCERS (2020)
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
Lisa M. Butler et al.
ADVANCED DRUG DELIVERY REVIEWS (2020)
Role of bioactive sphingolipids in physiology and pathology
Ana Gomez-Larrauri et al.
LIPID MEDIATORS (2020)
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells
Teresa Manzo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Ferroptosis, necroptosis, and pyroptosis in anticancer immunity
Rong Tang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Targeting Lipid Metabolism in Liver Cancer
Malak Alannan et al.
BIOCHEMISTRY (2020)
Lipids in the tumor microenvironment: From cancer progression to treatment
Kevin C. Corn et al.
PROGRESS IN LIPID RESEARCH (2020)
PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction
Xiaozhe Yin et al.
CELL REPORTS (2020)
Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells
Bowen Wu et al.
CELL METABOLISM (2020)
Development and Validation of a Novel 11-Gene Prognostic Model for Serous Ovarian Carcinomas Based on Lipid Metabolism Expression Profile
Mingjun Zheng et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Metabolic Constants and Plasticity of Cancer Cells in a Limiting Glucose and Glutamine Microenvironment-A Pyruvate Perspective
Angela M. Otto
FRONTIERS IN ONCOLOGY (2020)
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis
Xiao-Yi Lu et al.
NATURE (2020)
Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment
Lara P. Fernandez et al.
FRONTIERS IN ONCOLOGY (2020)
The role of ubiquitination in tumorigenesis and targeted drug discovery
Lu Deng et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression
Pieter Goossens et al.
CELL METABOLISM (2019)
Post-translational modifications and chromatin dynamics
Thomas O. Tolsma et al.
DNA PACKAGING: NUCLEOSOME AND CHROMATIN (2019)
Exosomes in the tumor microenvironment as mediators of cancer therapy resistance
Irene Li et al.
MOLECULAR CANCER (2019)
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
Kim Vriens et al.
NATURE (2019)
Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
Xiaoyun Li et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
Critical role of AMPK in redox regulation under glucose starvation
Yi Ren et al.
REDOX BIOLOGY (2019)
Beyond the tumour microenvironment
Lucie Laplane et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
Weimin Wang et al.
NATURE (2019)
Fatty acid transport protein 2 reprograms neutrophils in cancer
Filippo Veglia et al.
NATURE (2019)
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins
Jian Xiao et al.
SCIENCE CHINA-LIFE SCIENCES (2019)
Control of Tyrosine Kinase Signalling by Small Adaptors in Colorectal Cancer
Rudy Mevizou et al.
CANCERS (2019)
Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data
Yang Hao et al.
BMC BIOINFORMATICS (2019)
The Tumor Microenvironment Innately Modulates Cancer Progression
Dominique C. Hinshaw et al.
CANCER RESEARCH (2019)
Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer
Matteo Ligorio et al.
CELL (2019)
Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
Chang Liu et al.
IMMUNITY (2019)
Acetate Metabolism in Physiology, Cancer, and Beyond
Shree Bose et al.
TRENDS IN CELL BIOLOGY (2019)
Hepatic Tumor Microenvironments and Effects on NK Cell Phenotype and Function
Julian Pineiro Fernandez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Effects of Post-translational Modifications on Membrane Localization and Signaling of Prostanoid GPCR-G Protein Complexes and the Role of Hypoxia
Anurag S. Sikarwar et al.
JOURNAL OF MEMBRANE BIOLOGY (2019)
The emergence of protein arginine methyltransferases in skeletal muscle and metabolic disease
Tiffany L. vanLieshout et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2019)
Crosstalk of intracellular post-translational modifications in cancer
Zheng Wu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)
Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma
Qiming Zhang et al.
CELL (2019)
Even Cancer Cells Watch Their Cholesterol!
Romain Riscal et al.
MOLECULAR CELL (2019)
Regulation of glucose and lipid metabolism in health and disease
Ligong Chen et al.
SCIENCE CHINA-LIFE SCIENCES (2019)
Phosphorylation status at Smad3 linker region modulates transforming growth factor-β-induced epithelial-mesenchymal transition and cancer progression
Akira Ooshima et al.
CANCER SCIENCE (2019)
Insights into how phosphorylation of estrogen receptor at serine 305 modulates tamoxifen activity in breast cancer
Irida Kastrati et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)
PKCζ Phosphorylates SIRT6 to Mediate Fatty Acid β-Oxidation in Colon Cancer Cells
Tian Gao et al.
NEOPLASIA (2019)
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
Imanol Zubiete-Franco et al.
EBIOMEDICINE (2019)
Regulation of post-translational modification in breast cancer treatment
Kyung-Sun Heo
BMB REPORTS (2019)
Cold Tumors: A Therapeutic Challenge for Immunotherapy
Paola Bonaventura et al.
FRONTIERS IN IMMUNOLOGY (2019)
Differential Regulation of Human Treg and Th17 Cells by Fatty Acid Synthesis and Glycolysis
Deborah Cluxton et al.
FRONTIERS IN IMMUNOLOGY (2019)
Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells
Rain R. Chen et al.
COMMUNICATIONS BIOLOGY (2019)
Immune checkpoint inhibitors in cancer therapy: a focus on T-regulatory cells
Varun Sasidharan Nair et al.
IMMUNOLOGY AND CELL BIOLOGY (2018)
Lipid metabolism and lipophagy in cancer
Meenu Maan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Molecular Actions of PPARα in Lipid Metabolism and Inflammation
Nadia Bougarne et al.
ENDOCRINE REVIEWS (2018)
Paracrine Wnt5a-beta-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
Fei Zhao et al.
IMMUNITY (2018)
Notch1 signaling in melanoma cells promoted tumor-induced immunosuppression via upregulation of TGF-β1
Zike Yang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Is ABCA1 a lipid transfer protein?
Michael C. Phillips
JOURNAL OF LIPID RESEARCH (2018)
PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis
Ao Hu et al.
JOURNAL OF LIPID RESEARCH (2018)
Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration
Qi Zhang et al.
MOLECULAR IMMUNOLOGY (2018)
Post-translational modifications of transporters
Lindsay C. Czuba et al.
PHARMACOLOGY & THERAPEUTICS (2018)
Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target
Dabin Liu et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate
Terytty Yang Li et al.
Nature Communications (2018)
Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments
Christopher Ecker et al.
CELL REPORTS (2018)
Targeting CD36 as Biomarker for Metastasis Prognostic: How Far from Translation into Clinical Practice?
Ana-Maria Enciu et al.
BIOMED RESEARCH INTERNATIONAL (2018)
ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism
Carlotta Granchi
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer
Viktor Brovkovych et al.
ONCOGENESIS (2018)
Investigation of post-translational modifications in type 2 diabetes
Bhaswati Chatterjee et al.
CLINICAL PROTEOMICS (2018)
Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity
Hui-Ming Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
Sam A Menzies et al.
eLife (2018)
Lipid metabolism reprogramming and its potential targets in cancer
Chunming Cheng et al.
CANCER COMMUNICATIONS (2018)
SUMOylation and phosphorylation cross-talk in hepatocellular carcinoma
Maria Lauda Tomasi et al.
TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY (2018)
Fatty acid synthase (FASN) as a therapeutic target in breast cancer
Javier A. Menendez et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2017)
The story of protein arginine methylation: characterization, regulation, and function
Chao Peng et al.
EXPERT REVIEW OF PROTEOMICS (2017)
SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
Chun-Ping Cui et al.
GUT (2017)
Inhibition of the Sterol Regulatory Element-Binding Protein Pathway Suppresses Hepatocellular Carcinoma By Repressing Inflammation in Mice
Na Li et al.
HEPATOLOGY (2017)
Tumor-associated macrophages: implications in cancer immunotherapy
Amy J. Petty et al.
IMMUNOTHERAPY (2017)
Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver
Seonghwan Hwang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Emerging roles of lipid metabolism in cancer metastasis
Xiangjian Luo et al.
MOLECULAR CANCER (2017)
Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling
Xu Xiao et al.
MOLECULAR CELL (2017)
SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology
Hitoshi Shimano et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
Phosphorylation: Implications in Cancer
Vishakha Singh et al.
PROTEIN JOURNAL (2017)
A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR
Stephanie Bilodeau et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2017)
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis
Anke Loregger et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
Metabolic Reprogramming in Glioma
Marie Strickland et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)
Hepatic stellate cell-specific deletion of SIRT1 exacerbates liver fibrosis in mice
Min Li et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
Marcos Rios Garcia et al.
CELL METABOLISM (2017)
AMPK signalling in health and disease
David Carling
CURRENT OPINION IN CELL BIOLOGY (2017)
Tumor microenvironment and therapeutic response
Ting Wu et al.
CANCER LETTERS (2017)
SUMOylation of large tumor suppressor 1 at Lys751 attenuates its kinase activity and tumor-suppressor functions
Liu Mei et al.
CANCER LETTERS (2017)
Macrophage-mediated cholesterol handling in atherosclerosis
Dimitry A. Chistiakov et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
Protein acetylation in metabolism - metabolites and cofactors
Keir J. Menzies et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Liver Cancer: Connections with Obesity, Fatty Liver, and Cirrhosis
Andrea Marengo et al.
ANNUAL REVIEW OF MEDICINE, VOL 67 (2016)
Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth
Huai-Peng Lin et al.
CANCER RESEARCH (2016)
Arginine Methylation of SREBP1a via PRMT5 Promotes De Novo Lipogenesis and Tumor Growth
Liu Liu et al.
CANCER RESEARCH (2016)
The phosphorylation-dependent regulation of nuclear SREBP1 during mitosis links lipid metabolism and cell growth
Maria Teresa Bengoechea-Alonso et al.
CELL CYCLE (2016)
AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival
Rigel J. Kishton et al.
CELL METABOLISM (2016)
Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint
Key-Hwan Lim et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
AMPK activates LXRα and ABCA1 expression in human macrophages
Marina Kemmerer et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)
Post-translational modifications of FOXO family proteins
Ziyao Wang et al.
MOLECULAR MEDICINE REPORTS (2016)
Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
Wei Yang et al.
NATURE (2016)
Human Oncogenic Herpesvirus and Post-translational Modifications - Phosphorylation and SUMOylation
Pei-Ching Chang et al.
FRONTIERS IN MICROBIOLOGY (2016)
Fundamentals of cancer metabolism
Ralph J. DeBerardinis et al.
SCIENCE ADVANCES (2016)
The multifaceted roles of fatty acid synthesis in cancer
Florian Roehrig et al.
NATURE REVIEWS CANCER (2016)
Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth
Chunming Cheng et al.
CANCER CELL (2015)
Uncoupling Nuclear Receptor LXR and Cholesterol Metabolism in Cancer
Fabiola Bovenga et al.
CELL METABOLISM (2015)
Molecular Pathways: Fatty Acid Synthase
Suzanne F. Jones et al.
CLINICAL CANCER RESEARCH (2015)
DeSUMOylation: An Important Therapeutic Target and Protein Regulatory Event
Chun-Jie Huang et al.
DNA AND CELL BIOLOGY (2015)
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
Michal Pawlak et al.
JOURNAL OF HEPATOLOGY (2015)
Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver
Xiujuan Zhang et al.
JOURNAL OF LIPID RESEARCH (2015)
Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators
Maximillian A. Rogers et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
Estrogen receptor alpha phosphorylation and its functional impact in human breast cancer
Muralidharan Anbalagan et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)
Co-targeting cancer drug escape pathways confers clinical advantage for multi-target anticancer drugs
Lin Tao et al.
PHARMACOLOGICAL RESEARCH (2015)
Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation
Sean J. Humphrey et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)
A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity
Dong-Hyun Kim et al.
EMBO JOURNAL (2015)
Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
Aritro Nath et al.
SCIENTIFIC REPORTS (2015)
Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids
Julian Stevenson et al.
BIOCHEMICAL JOURNAL (2014)
Docosahexaenoic acid inhibits insulin-induced activation of sterol regulatory-element binding protein 1 and cyclooxygenase-2 expression through upregulation of SIRT1 in human colon epithelial cells
Na-Young Song et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Cbx4 Governs HIF-1α to Potentiate Angiogenesis of Hepatocellular Carcinoma by Its SUMO E3 Ligase Activity
Jie Li et al.
CANCER CELL (2014)
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
Hayley M. O'Neill et al.
DIABETOLOGIA (2014)
Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1
Dhanya K. Nambiar et al.
ONCOTARGET (2014)
Mitochondrial Phosphorylation in Apoptosis: Flipping the Death Switch
Natalie M. Niemi et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Cellular Fatty Acid Metabolism and Cancer
Erin Currie et al.
CELL METABOLISM (2013)
Post-translational Modifications and Mass Spectrometry Detection
Andre M. N. Silva et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Aberrant Lipid Metabolism: An Emerging Diagnostic and Therapeutic Target in Ovarian Cancer
Carmen E. Pyragius et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Modulation of Fatty Acid Synthase Degradation by Concerted Action of p38 MAP Kinase, E3 Ligase COP1, and SH2-Tyrosine Phosphatase Shp2
Jianxiu Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC
Shu-Ting Yang et al.
JOURNAL OF HEPATOLOGY (2013)
Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition
Giada Gelsomino et al.
MOLECULAR CANCER (2013)
Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth
Ruiting Lin et al.
MOLECULAR CELL (2013)
Evolution and functional cross-talk of protein post-translational modifications
Pedro Beltrao et al.
MOLECULAR SYSTEMS BIOLOGY (2013)
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
Yoko Kidani et al.
NATURE IMMUNOLOGY (2013)
Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4
Ombretta Foresti et al.
ELIFE (2013)
Phosphorylation-Dependent Protein-Protein Interaction Modules As Potential Molecular Targets for Cancer Therapy
Nobumoto Watanabe et al.
CURRENT DRUG TARGETS (2012)
Connecting mTORC1 signaling to SREBP-1 activation
Inan Bakan et al.
CURRENT OPINION IN LIPIDOLOGY (2012)
Lipid metabolism in cancer
Claudio R. Santos et al.
FEBS JOURNAL (2012)
GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
Shu-Yong Lin et al.
SCIENCE (2012)
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation
Donald B. Jump et al.
BIOCHEMICAL PHARMACOLOGY (2011)
meso-Dihydroguaiaretic Acid Inhibits Hepatic Lipid Accumulation by Activating AMP-Activated Protein Kinase in Human HepG2 Cells
Myoung-Su Lee et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Yu Li et al.
CELL METABOLISM (2011)
The role of deubiquitinating enzymes in apoptosis
Suresh Ramakrishna et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma
Diego F. Calvisi et al.
GASTROENTEROLOGY (2011)
Reversible SUMOylation of TBL1-TBLR1 Regulates β-Catenin-Mediated Wnt Signaling
Hyo-Kyoung Choi et al.
MOLECULAR CELL (2011)
LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor
Noam Zelcer et al.
SCIENCE (2009)
SUMOylation Regulates Nuclear Localization of Kruppel-like Factor 5
James X. Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Chemical inhibition of Acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
Annelies Beckers et al.
CANCER RESEARCH (2007)
Mechanisms of specificity in protein phosphorylation (vol 8, pg 530, 2007)
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
Charles W. Pemble et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Mechanisms of specificity in protein phosphorylation
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism
Ling Qi et al.
SCIENCE (2006)
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7
A Sundqvist et al.
CELL METABOLISM (2005)
Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4
AR Weatherill et al.
JOURNAL OF IMMUNOLOGY (2005)
Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability
C Caron et al.
BIOESSAYS (2005)
分享论文
