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STEM CELLS (2012)
Circulating Tumor Cells as a Window on Metastasis Biology in Lung Cancer
Jian-Mei Hou et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis
Myriam Labelle et al.
CANCER CELL (2011)
Snail2 is an Essential Mediator of Twist1-Induced Epithelial Mesenchymal Transition and Metastasis
Esmeralda Casas et al.
CANCER RESEARCH (2011)
Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness
Jun Hong et al.
CANCER RESEARCH (2011)
EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
Carmen S. Tellez et al.
CANCER RESEARCH (2011)
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
Peter Friedl et al.
CELL (2011)
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
Helge Siemens et al.
CELL CYCLE (2011)
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis
Junjiang Fu et al.
CELL RESEARCH (2011)
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
Simone Brabletz et al.
EMBO JOURNAL (2011)
Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition
Natlia Dave et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells
Noortje A. M. Bax et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
Taewan Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription
Hector L. Franco et al.
NUCLEIC ACIDS RESEARCH (2011)
Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity
Robert Strauss et al.
PLOS ONE (2011)
Molecular interactions in cancer cell metastasis
Susan A. Brooks et al.
ACTA HISTOCHEMICA (2010)
Protein Kinase D1 Suppresses Epithelial-to-Mesenchymal Transition through Phosphorylation of Snail
Cheng Du et al.
CANCER RESEARCH (2010)
Cell Polarity in Eggs and Epithelia: Parallels and Diversity
Daniel St Johnston et al.
CELL (2010)
Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells
R. David Hawkins et al.
CELL STEM CELL (2010)
The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1
Yiwei Lin et al.
EMBO JOURNAL (2010)
miR-194 Is a Marker of Hepatic Epithelial Cells and Suppresses Metastasis of Liver Cancer Cells in Mice
Zhipeng Meng et al.
HEPATOLOGY (2010)
TGF-β-induced MiR-491-5p Expression Promotes Par-3 Degradation in Rat Proximal Tubular Epithelial Cells
Qin Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Visualizing extravasation dynamics of metastatic tumor cells
Konstantin Stoletov et al.
JOURNAL OF CELL SCIENCE (2010)
The basics of epithelial-mesenchytnal transition (vol 119, pg 1420, 2009)
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Cell mechanics and the cytoskeleton
Daniel A. Fletcher et al.
NATURE (2010)
Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
Muh-Hwa Yang et al.
NATURE CELL BIOLOGY (2010)
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Li Ma et al.
NATURE CELL BIOLOGY (2010)
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
E. Sanchez-Tillo et al.
ONCOGENE (2010)
Requirement of the histone demethylase LSD1 in Snail-mediated transcriptional repression during epithelial-mesenchymal transition
T. Lin et al.
ONCOGENE (2010)
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
A. Singh et al.
ONCOGENE (2010)
Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multilineage Differentiation Potential Similar to Mesenchymal Stem Cells
Venkata Lokesh Battula et al.
STEM CELLS (2010)
HMGA2 Maintains Oncogenic RAS-Induced Epithelial-Mesenchymal Transition in Human Pancreatic Cancer Cells
Sugiko Watanabe et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
EMT, the cytoskeleton, and cancer cell invasion
Mahmut Yilmaz et al.
CANCER AND METASTASIS REVIEWS (2009)
Cancer Metastasis Is Accelerated through Immunosuppression during Snail-induced EMT of Cancer Cells
Chie Kudo-Saito et al.
CANCER CELL (2009)
Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion
Yadi Wu et al.
CANCER CELL (2009)
Translational Activation of Snail1 and Other Developmentally Regulated Transcription Factors by YB-1 Promotes an Epithelial-Mesenchymal Transition
Valentina Evdokimova et al.
CANCER CELL (2009)
Tumor Self-Seeding by Circulating Cancer Cells
Mi-Young Kim et al.
CELL (2009)
Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
Yohei Shimono et al.
CELL (2009)
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery et al.
CELL (2009)
Defining the Role of Integrin αvβ6 in Cancer
A. Bandyopadhyay et al.
CURRENT DRUG TARGETS (2009)
Small C-terminal Domain Phosphatase Enhances Snail Activity through Dephosphorylation
Yadi Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
Li-Bing Song et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
Ulrich Wellner et al.
NATURE CELL BIOLOGY (2009)
Cancer stem cells: mirage or reality?
Piyush B. Gupta et al.
NATURE MEDICINE (2009)
Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1
Ichiro Ota et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
NATURE REVIEWS CANCER (2009)
Hypoxia-inducible factor-1 alpha and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients
Galatea Kallergi et al.
BREAST CANCER RESEARCH (2009)
Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation
Courtney M. Williams et al.
CANCER RESEARCH (2008)
Tissue Factor Regulation by Epidermal Growth Factor Receptor and Epithelial-to-Mesenchymal Transitions: Effect on Tumor Initiation and Angiogenesis
Chloe C. Milsom et al.
CANCER RESEARCH (2008)
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
Cameron P. Bracken et al.
CANCER RESEARCH (2008)
Epithelial-Mesenchymal Transition Induced by Growth Suppressor p12CDK2-AP1 Promotes Tumor Cell Local Invasion but Suppresses Distant Colony Growth
Takanori Tsuji et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Epithelial to mesenchymal transition during gastrulation: An embryological view
Yukiko Nakaya et al.
DEVELOPMENT GROWTH & DIFFERENTIATION (2008)
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
Ulrike Burk et al.
EMBO REPORTS (2008)
Lamellipodia and filopodia in metastasis and invasion
Laura M. Machesky
FEBS LETTERS (2008)
Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor
Minhui Lee et al.
JOURNAL OF CELL SCIENCE (2008)
MicroRNA-155 Is Regulated by the Transforming Growth Factor β/Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA
William Kong et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Polycomb complex 2 is required for E-cadherin repression by the snail1 transcription factor
Nicolas Herranz et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression
Zhaoyuan Hou et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Transforming growth factor-beta 1 promotes matrix metalloproteinase-9-mediated ora cancer invasion through snail expression
Limin Sun et al.
MOLECULAR CANCER RESEARCH (2008)
Direct regulation of TWIST by HIF-1α promotes metastasis
Muh-Hwa Yang et al.
NATURE CELL BIOLOGY (2008)
The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
NATURE CELL BIOLOGY (2008)
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
Cecilia Sahlgren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients
Galatea Kallergi et al.
BREAST CANCER RESEARCH (2008)
The emerging roles of forkhead box (Fox) proteins in cancer
Stephen S. Myatt et al.
NATURE REVIEWS CANCER (2007)
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
Christophe Ginestier et al.
CELL STEM CELL (2007)
The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
K. Aigner et al.
ONCOGENE (2007)
Mechanisms of specificity in protein phosphorylation (vol 8, pg 530, 2007)
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Mechanisms of specificity in protein phosphorylation
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and -independent mechanisms
Joseph S. Palumbo et al.
BLOOD (2007)
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Hector Peinado et al.
NATURE REVIEWS CANCER (2007)
Phase I evaluation of a fully human anti-αv integrin monoclonal antibody (CNTO 95) in patients with advanced solid tumors
Saifee A. Mullamitha et al.
CLINICAL CANCER RESEARCH (2007)
Matrix metalloproteinases (MMPs): Chemical-biological functions and (Q)SARs
Rajeshwar P. Verma et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Epithelial stem cells: Turning over new leaves
Cedric Blanpain et al.
CELL (2007)
A Wnt-Axin2-GSK3β cascade regulates Snail1 activity in breast cancer cells
Jong In Yook et al.
NATURE CELL BIOLOGY (2006)
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
Terence K. Lee et al.
CLINICAL CANCER RESEARCH (2006)
Regulation of vimentin by SIP1 in human epithelial breast tumor cells
S. Bindels et al.
ONCOGENE (2006)
Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development
D Sakai et al.
DEVELOPMENT (2006)
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JM Lee et al.
JOURNAL OF CELL BIOLOGY (2006)
Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin
JY Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Opinion - Migrating cancer stem cells - an integrated concept of malignant tumour progression
T Brabletz et al.
NATURE REVIEWS CANCER (2005)
Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor
M Jordà et al.
JOURNAL OF CELL SCIENCE (2005)
The Snail genes as inducers of cell movement and survival: implications in development and cancer
A Barrallo-Gimeno et al.
DEVELOPMENT (2005)
Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions
ZB Yang et al.
CANCER RESEARCH (2005)
Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells
A Miyoshi et al.
BRITISH JOURNAL OF CANCER (2004)
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
U Cavallaro et al.
NATURE REVIEWS CANCER (2004)
Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
M Kajita et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Stem colls and cancer: The polycomb connection
ME Valk-Lingbeek et al.
CELL (2004)
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
J Yang et al.
CELL (2004)
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial-mesenchymal transition
BHP Zhou et al.
NATURE CELL BIOLOGY (2004)
Opposing functions of ZEB proteins in the regulation of the TGFβ/BMP signaling pathway
AA Postigo
EMBO JOURNAL (2003)
Inhibition of integrin α5β1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
O Stoeltzing et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions:: a comparison with Snail and E47 repressors
V Bolós et al.
JOURNAL OF CELL SCIENCE (2003)
Snail precedes Slug in the genetic cascade required for the specification and migration of the Xenopus neural crest
MJ Aybar et al.
DEVELOPMENT (2003)
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
Y Fujita et al.
NATURE CELL BIOLOGY (2002)
Methylation of the E-cadherin gene in bladder neoplasia and in normal urothelial epithelium from elderly individuals
DM Bornman et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Evidence for a function of CtBP in epithelial gene regulation and anoikis
ML Grooteclaes et al.
ONCOGENE (2000)
E-cadherin gene promoter hypermethylation in primary human gastric carcinomas
G Tamura et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
A Cano et al.
NATURE CELL BIOLOGY (2000)
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