Synthesis and Chemosensory Properties of New Cyanosubstituted 2,2'-Bipyridine Derivatives

A series of novel 6-oxo-1,6-dihydro-[2,2'-bipyridine]-5-carbonitriles has been synthesized and characterized. Their photophysical properties in DMSO solution and aqueous medium as well as fluorescence response to the presence of metal ions have been investigated. The obtained 4-(4-methoxyphenyl)-6-oxo-1,6-dihydro-[2,2'-bipyridine]-5-carbonitrile has been shown as a selective fluorescent turn-ON probe for Cd2+ ions with LoD 0.359 mu M, 1:1 metal-ligand ratio and binding constant of 5.2 x 10(4) M-1.

Automated summary

A series of novel 6-oxo-1,6-dihydro-[2,2'-bipyridine]-5-carbonitriles were synthesized and characterized. One of the obtained compounds showed selective fluorescent turn-ON response towards Cd2+ ions.