☆ 4.7 Article

Approach to the Patient With Nonalcoholic Fatty Liver Disease

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Gastroenterology & Hepatology

Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals

Alessandro Mantovani et al.

Summary: A meta-analysis of observational studies demonstrated that non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of new-onset heart failure (HF). This risk is independent of other common cardiovascular risk factors.

GUT (2023)

添加到收藏夹

Article Endocrinology & Metabolism

Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease

Sami Qadri et al.

Summary: This study investigated the impact of obesity on the performance of liver fibrosis biomarkers in NAFLD and found that ADAPT and FIB-4 are the best-performing biomarkers in obese patients, unaffected by body mass index.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Advancing the global public health agenda for NAFLD: a consensus statement

Jeffrey Lazarus et al.

Summary: Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects a significant portion of the global adult population, but has received little attention from the global public health community. This has led to a lack of inclusion of NAFLD in national and international strategies and policies for non-communicable diseases, highlighting the need for a more comprehensive public health response to the disease.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2022)

添加到收藏夹

Review Endocrinology & Metabolism

A global view of the interplay between non-alcoholic fatty liver disease and diabetes

Norbert Stefan et al.

Summary: Non-alcoholic fatty liver disease (NAFLD) has become an epidemic, associated with the increasing prevalence of obesity and type 2 diabetes, and its pathophysiology is closely related to the development of communicable diseases such as COVID-19. Understanding the relationship between diabetes and NAFLD is important for disease treatment. Identifying different pathological mechanisms of NAFLD among different groups of diabetes patients may improve diagnosis and prediction.

LANCET DIABETES & ENDOCRINOLOGY (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis

Ferenc Emil Mozes et al.

Summary: Liver biopsy is still necessary for fibrosis staging in patients with non-alcoholic fatty liver disease. This study evaluated the diagnostic performance of liver stiffness measurement, FIB-4 Index, and NAFLD Fibrosis Score, and showed that sequential combinations of markers can reduce the need for liver biopsies.

GUT (2022)

添加到收藏夹

Article Endocrinology & Metabolism

American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD)

Kenneth Cusi et al.

Summary: This article provides evidence-based recommendations for the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) for endocrinologists, primary care clinicians, and other stakeholders. The guideline includes 34 evidence-based clinical practice recommendations and contains relevant citations.

ENDOCRINE PRACTICE (2022)

添加到收藏夹

Review Endocrinology & Metabolism

The Emerging Role of Glucagon-like Peptide-1 Receptor Agonists for the Management of NAFLD

Chandani Patel Chavez et al.

Summary: The burden of cirrhosis from nonalcoholic fatty liver disease (NAFLD) is becoming widespread in the United States. There needs to be greater awareness among endocrinologists, who often see but may miss the diagnosis in adults with obesity or type 2 diabetes mellitus (T2D) who are at high risk. Recent studies suggest that glucagon-like peptide-1 receptor agonists (GLP-1RAs) have beneficial effects on nonalcoholic steatohepatitis (NASH) in this population.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

添加到收藏夹

Article Endocrinology & Metabolism

Nonalcoholic Fatty Liver Disease in Women and Girls With Polycystic Ovary Syndrome

Claire Falzarano et al.

Summary: Recent research has shown a high prevalence of nonalcoholic fatty liver disease (NAFLD) in women with polycystic ovary syndrome (PCOS). Women with normal weight can also develop NAFLD. The majority of studies focus on adult, premenopausal women and little attention has been given to young and adolescent women with NAFLD. Future research should include more diverse populations and study the contribution of excess androgens and insulin resistance to NAFLD risk in women with PCOS of varying weights, ages, and ethnicities.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

添加到收藏夹

Article Endocrinology & Metabolism

Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

Amalia Gastaldelli et al.

Summary: Tirzepatide demonstrated significant reductions in liver fat content, visceral adipose tissue, and abdominal subcutaneous adipose tissue in patients with type 2 diabetes in the SURPASS-3 study.

LANCET DIABETES & ENDOCRINOLOGY (2022)

添加到收藏夹

Review Endocrinology & Metabolism

Metabolic mechanisms for and treatment of NAFLD or NASH occurring after liver transplantation

Amedeo Lonardo et al.

Summary: This review outlines the occurrence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in liver transplant recipients, specifically those with NASH-related cirrhosis. It highlights the increasing prevalence of NAFLD and NASH, and their impact on liver transplantation. The review also discusses the higher risk of waiting-list mortality and post-transplant complications such as recurrent liver disease and cardiometabolic issues in patients with NASH-related cirrhosis. Optimal therapeutic approaches, including tailored immunosuppression and lifestyle changes, are also addressed.

NATURE REVIEWS ENDOCRINOLOGY (2022)

添加到收藏夹

Review Gastroenterology & Hepatology

Prognostic accuracy of FIB-4, NAFLD fibrosis score and APRI for NAFLD-related events: A systematic review

Jenny Lee et al.

Summary: This study synthesized the existing literature on the ability of FIB-4, NFS, and APRI models in prognosticating NAFLD-related events. The results showed that these models have demonstrated good ability to risk stratify patients for liver-related morbidity and mortality, with inconsistent performance in predicting change in fibrosis stage. Further head-to-head studies are needed to validate their performance and refine models for prognosticating NAFLD events.

LIVER INTERNATIONAL (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Presence of Liver Steatosis Is Associated With Greater Diabetes Remission After Gastric Bypass Surgery

Roman Vangoitsenhoven et al.

Summary: This study suggests that presence of liver steatosis in patients with T2DM undergoing bariatric surgery is associated with better long-term glycemic outcomes, indicating distinct variants of T2DM with different metabolic responses to surgical weight loss.

DIABETES CARE (2021)

添加到收藏夹

Article Endocrinology & Metabolism

High Prevalence of Advanced Liver Fibrosis Assessed by Transient Elastography Among US Adults With Type 2 Diabetes

Stefano Ciardullo et al.

Summary: The prevalence of liver steatosis and fibrosis is high in patients with T2DM from the United States, with obesity being a major risk factor. Screening for these conditions among patients with diabetes is recommended based on the study results.

DIABETES CARE (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Advanced Liver Fibrosis Is Common in Patients With Type 2 Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening

Romina Lomonaco et al.

Summary: This study assessed the prevalence of NAFLD and liver fibrosis in patients with type 2 diabetes mellitus, revealing that at least 15% of patients with T2DM and NAFLD have moderate-to-advanced fibrosis. Screening for liver disease can be enhanced using imaging and plasma diagnostic panels, as AST/ALT alone are inadequate as initial screening markers.

DIABETES CARE (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis

Zobair M. Younossi et al.

Summary: In patients with advanced NASH, baseline NIT scores and their changes over time are predictive factors for adverse clinical and PROs outcomes. Patients with higher NIT scores are more likely to experience disease progression and impaired PROs, while those with decreasing NIT scores may see improvements in PRO scores.

GASTROENTEROLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review

Zobair M. Younossi et al.

Summary: NAFLD is a leading cause of chronic liver disease globally, affecting over 25% of the population. Lifestyle modification for weight loss is the primary intervention for patients with NAFLD. Evidence-based interventions and best practice advice are provided for clinical management of NAFLD.

GASTROENTEROLOGY (2021)

添加到收藏夹

Article Medicine, General & Internal

Association of Bariatric Surgery With Major Adverse Liver and Cardiovascular Outcomes in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis

Ali Aminian et al.

Summary: Among patients with NASH and obesity, bariatric surgery was associated with a significantly lower risk of incident major adverse liver outcomes and MACE compared with nonsurgical management.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Medicine, General & Internal

Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease

Arun J. Sanyal et al.

Summary: In this study involving patients with nonalcoholic fatty liver disease, advanced fibrosis stages F3 and F4 were associated with increased risks of liver-related complications and death over a median of 4 years of follow-up. Advanced fibrosis was also related to an increased incidence of liver decompensation events.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Review Endocrinology & Metabolism

The effect of the magnitude of weight loss on non-alcoholic fatty liver disease: A systematic review and meta-analysis

Dimitrios A. Koutoukidis et al.

Summary: Studies have shown that even modest weight loss can lead to clinically significant improvements in NAFLD, with greater weight loss associated with greater benefits. There is a dose-response relationship between weight loss and liver inflammation, steatosis, and resolution of NAFLD or NASH.

METABOLISM-CLINICAL AND EXPERIMENTAL (2021)

添加到收藏夹

Review Nutrition & Dietetics

Reduction of Major Adverse Cardiovascular Events (MACE) after Bariatric Surgery in Patients with Obesity and Cardiovascular Diseases: A Systematic Review and Meta-Analysis

Andryanto Sutanto et al.

Summary: Cardiovascular diseases are the primary cause of death globally, with obesity as a major risk factor. Lifestyle modifications and bariatric surgery are common approaches for managing obesity. Research suggests that bariatric surgery may be beneficial in reducing Major Adverse Cardiovascular Events in patients with obesity and CVDs.

NUTRIENTS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Implementing a pharmacist-led transition of care model for posttransplant hyperglycemia

Vincent Do et al.

Summary: A pharmacist-managed PTHG program successfully reduced hospitalizations and emergency department visits due to hyperglycemia for kidney transplant recipients, demonstrating the importance of incorporating such programs into standard care to improve patient outcomes.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Prospective evaluation of the prevalence of non-alcoholic fatty liver disease and steatohepatitis in a large middle-aged US cohort

Stephen A. Harrison et al.

Summary: In a cohort of asymptomatic middle-aged Americans, the prevalence of NAFLD was 38%, NASH was 14%, and significant liver fibrosis was present in 6% of the participants.

JOURNAL OF HEPATOLOGY (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

The complex link between NAFLD and type 2 diabetes mellitus - mechanisms and treatments

Giovanni Targher et al.

Summary: Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) have a complex relationship with each other, influencing the risk of adverse clinical outcomes. The severity of NAFLD is directly related to the risk of developing T2DM, while improvement of NAFLD may lower the risk of T2DM.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Medicine, General & Internal

A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis

Philip N. Newsome et al.

Summary: This phase 2 trial demonstrated that treatment with semaglutide resulted in a significantly higher percentage of patients with NASH resolution compared to placebo in patients with NASH, but did not show a significant between-group difference in the percentage of patients with an improvement in fibrosis stage.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Review Endocrinology & Metabolism

Preparing for the NASH Epidemic: A Call to Action

Fasiha Kanwal et al.

Summary: NAFLD and NASH are common conditions with a rising burden, but there are significant gaps between clinical guidelines and practice in managing these diseases. An international conference of experts from various countries was convened to discuss global burden, screening, risk stratification, diagnosis, and management, leading to the development of a comprehensive unified strategy for care.

DIABETES CARE (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Pioglitazone even at low dosage improves NAFLD in type 2 diabetes: clinical and pathophysiological insights from a subgroup of the TOSCA.IT randomised trial

Giuseppe Della Pepa et al.

Summary: The study found that pioglitazone significantly improved NAFLD indicators and insulin resistance in patients with T2D, while sulphonylureas did not have this effect. In addition, the beneficial effects of pioglitazone on NAFLD were independent of blood glucose control.

DIABETES RESEARCH AND CLINICAL PRACTICE (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease

Fasiha Kanwal et al.

Summary: NAFLD is a common disease that affects a significant proportion of US adults. Management typically occurs in primary care or endocrine clinics, where accurate staging for fibrosis risk through screening is crucial, requiring consistent, timely, evidence-based, and easily testable management processes.

GASTROENTEROLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

First-in-Asian double-blind randomized trial to assess the efficacy and safety of insulin sensitizer in nonalcoholic steatohepatitis patients

Jee-Fu Huang et al.

Summary: The study demonstrated that pioglitazone was effective and safe in treating Asian NASH patients, leading to significant reductions in inflammation, improvement in liver fat, and no significant adverse events.

HEPATOLOGY INTERNATIONAL (2021)

添加到收藏夹

Article Medicine, General & Internal

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial

Julio Rosenstock et al.

Summary: Tirzepatide demonstrated significant improvements in glycemic control and body weight without increasing the risk of hypoglycemia. The safety profile was consistent with GLP-1 receptor agonists, suggesting a potential monotherapy use for the treatment of type 2 diabetes.

LANCET (2021)

添加到收藏夹

Article Medicine, General & Internal

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

Bernhard Ludvik et al.

Summary: The study aimed to compare the efficacy and safety of tirzepatide versus titrated insulin degludec in the treatment of type 2 diabetes. The results showed that tirzepatide had significant advantages in reducing HbA(1c) and bodyweight, and decreased the risk of hypoglycemia.

LANCET (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

PPAR-γ-induced changes in visceral fat and adiponectin levels are associated with improvement of steatohepatitis in patients with NASH

Amalia Gastaldelli et al.

Summary: The study found that PPAR-gamma agonists, along with an increase in ADPN levels, a decrease in VF, and an improvement in VF/SC fat distribution, are closely related to improving the pathological condition of patients with NASH.

LIVER INTERNATIONAL (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Defining comprehensive models of care for NAFLD

Jeffrey Lazarus et al.

Summary: The paper discusses seven comprehensive models of care for patients with non-alcoholic fatty liver disease (NAFLD) and provides eight recommendations for policymakers and practitioners to address the increasing demand for good practice care for NAFLD patients.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Medicine, General & Internal

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes

Juan P. Frias et al.

Summary: The study showed that Tirzepatide was both noninferior and superior to Semaglutide in terms of the mean change in glycated hemoglobin levels for patients with type 2 diabetes over 40 weeks. Additionally, reductions in body weight were greater with Tirzepatide compared to Semaglutide, with similar rates of gastrointestinal adverse events reported in both groups.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Type 2 diabetes mellitus increases the risk of hepatic fibrosis in individuals with obesity and nonalcoholic fatty liver disease

Diana Barb et al.

Summary: This study in the United States assessed the impact of diabetes mellitus on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis with advanced fibrosis prevalence in adults with overweight or obesity. The findings suggest that diabetes modestly impacted steatosis, primarily driven by obesity, and added significant risk of fibrosis to individuals with overweight or obesity, highlighting the importance of screening in adults with diabetes.

OBESITY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Severity of non-alcoholic steatohepatitis is not linked to testosterone concentration in patients with type 2 diabetes

Kristin Alexandra Dayton et al.

Summary: Through MR-spectroscopy imaging and liver biopsy research on male patients with T2DM, it was found that NAFLD is associated with lower testosterone levels, but not with the severity of liver necroinflammation or fibrosis.

PLOS ONE (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Effects of Mediterranean Diet in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Randomized Controlled Trials

Takumi Kawaguchi et al.

Summary: The Mediterranean Diet significantly improved hepatic steatosis and insulin resistance in patients with nonalcoholic fatty liver disease (NAFLD), making it a beneficial pharmaconutritional therapy for this condition.

SEMINARS IN LIVER DISEASE (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis

Alessandro Mantovani et al.

Summary: Studies have shown a significant association between non-alcoholic fatty liver disease (NAFLD) and increased risk of cardiovascular disease (CVD) incidence. The risk of fatal or non-fatal CVD events is moderately increased with NAFLD, and this risk escalates with the severity of NAFLD, particularly with higher fibrosis stages. These findings suggest that NAFLD may be an independent risk factor for CVD morbidity and mortality.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Epidemiology of chronic liver diseases in the USA in the past three decades

Zobair M. Younossi et al.

GUT (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Risks of Light and Moderate Alcohol Use in Fatty Liver Disease: Follow-Up of Population Cohorts

Fredrik Aberg et al.

HEPATOLOGY (2020)

添加到收藏夹

Article Surgery

Impact of sleeve gastrectomy and Roux-en-Y gastric bypass on biopsy-proven non-alcoholic fatty liver disease

Deepa V. Cherla et al.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Clinical Controversy in Transplantation: Tacrolimus Versus Cyclosporine in Statin Drug Interactions

Daniel R. Migliozzi et al.

ANNALS OF PHARMACOTHERAPY (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial

Sabine Kahl et al.

DIABETES CARE (2020)

添加到收藏夹

Article Surgery

Long-term outcomes in patients with obesity and renal disease after sleeve gastrectomy

Al-Faraaz Kassam et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Economic and Clinical Burden of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes in the US

Zobair M. Younossi et al.

DIABETES CARE (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Vitamin E Improves Transplant-Free Survival and Hepatic Decompensation Among Patients With Nonalcoholic Steatohepatitis and Advanced Fibrosis

Eduardo Vilar-Gomez et al.

HEPATOLOGY (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Time to Include Nonalcoholic Steatohepatitis in the Management of Patients With Type 2 Diabetes

Kenneth Cusi

DIABETES CARE (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Association Between Fibrosis Stage and Outcomes of Patients with Non-Alcoholic Fatty Liver Disease: a Systematic Review and Meta-Analysis

Rod S. Taylor et al.

GASTROENTEROLOGY (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

NAFLD and increased risk of cardiovascular disease: clinical associations, pathophysiological mechanisms and pharmacological implications

Giovanni Targher et al.

GUT (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population

Helene Gellert-Kristensen et al.

HEPATOLOGY (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

Qing Ye et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Repeated FIB-4 measurements can help identify individuals at risk of severe liver disease

Hannes Hagstrom et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Latin American Association for the study of the liver (ALEH) practice guidance for the diagnosis and treatment of non-alcoholic fatty liver disease

Juan Pablo Arab et al.

ANNALS OF HEPATOLOGY (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Changing trends of liver transplantation and mortality from non-alcoholic fatty liver disease

Avik Majumdar et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

添加到收藏夹

Review Endocrinology & Metabolism

Role of Agents for the Treatment of Diabetes in the Management of Nonalcoholic Fatty Liver Disease

Jeffrey Budd et al.

CURRENT DIABETES REPORTS (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Efficacy and Safety of Short- and Long-Acting Glucagon-Like Peptide 1 Receptor Agonists on a Background of Basal Insulin in Type 2 Diabetes: A Meta-analysis

Jessica A. Huthmacher et al.

DIABETES CARE (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

Mohammed Eslam et al.

HEPATOLOGY INTERNATIONAL (2020)

添加到收藏夹

Editorial Material Biochemistry & Molecular Biology

Cardiovascular risk in patients with nonalcoholic fatty liver disease: looking at the liver to shield the heart

Kenneth Cusi et al.

CURRENT OPINION IN LIPIDOLOGY (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Nonalcoholic Steatohepatitis Is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates

Zobair Younossi et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants

Cynthia Hsu et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals

Fateh Bazerbachi et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

添加到收藏夹

Article Endocrinology & Metabolism

The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients

Aino Latva-Rasku et al.

DIABETES CARE (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Accuracy of FibroScan Controlled Attenuation Parameter and Liver Stiffness Measurement in Assessing Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease

Peter J. Eddowes et al.

GASTROENTEROLOGY (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Management of dyslipidemia in adult solid organ transplant recipients

Bruce A. Warden et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2019)

添加到收藏夹

Editorial Material Gastroenterology & Hepatology

Incretin-Based Therapies for the Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes

Kenneth Cusi

HEPATOLOGY (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content

Yftach Gepner et al.

JOURNAL OF HEPATOLOGY (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Impact of Obesity and Alanine Aminotransferase Levels on the Diagnostic Accuracy for Advanced Liver Fibrosis of Noninvasive Tools in Patients With Nonalcoholic Fatty Liver Disease

Salvatore Petta et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2019)

添加到收藏夹

Article Endocrinology & Metabolism

Role of Vitamin E for Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized Controlled Trial

Fernando Bril et al.

DIABETES CARE (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

Liver Transplantation for Nonalcoholic Steatohepatitis: Pathophysiology of Recurrence and Clinical Challenges

Naga Swetha Samji et al.

DIGESTIVE DISEASES AND SCIENCES (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis

Zobair M. Younossi et al.

JOURNAL OF HEPATOLOGY (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels

Samer Gawrieh et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2019)

添加到收藏夹

Review Surgery

Systematic review and meta-analysis of Roux-en-Y gastric bypass against laparoscopic sleeve gastrectomy for amelioration of NAFLD using four criteria

Dustin Baldwin et al.

SURGERY FOR OBESITY AND RELATED DISEASES (2019)

添加到收藏夹

Review Immunology

Incidence and Risks for Nonalcoholic Fatty Liver Disease and Steatohepatitis Post-liver Transplant: Systematic Review and Meta-analysis

Naba Saeed et al.

TRANSPLANTATION (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-analysis

Yung Lee et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

Mohammad Shadab Siddiqui et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

添加到收藏夹

Article Nutrition & Dietetics

ESPEN guideline on clinical nutrition in liver disease

Mathias Plauth et al.

CLINICAL NUTRITION (2019)

添加到收藏夹

Article Endocrinology & Metabolism

Effect of canagliflozin treatment on hepatic triglyceride content and glucose metabolism in patients with type 2 diabetes

Kenneth Cusi et al.

DIABETES OBESITY & METABOLISM (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Causality between non-alcoholic fatty liver disease and risk of cardiovascular disease and type 2 diabetes: A meta-analysis with bias analysis

Amy E. Morrison et al.

LIVER INTERNATIONAL (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Association between non-alcoholic fatty liver disease and risk of atrial fibrillation in adult individuals: An updated meta-analysis

Alessandro Mantovani et al.

LIVER INTERNATIONAL (2019)

添加到收藏夹

Article Immunology

Management of Recurrent and De Novo NAFLD/NASH After Liver Transplantation

Giacomo Germani et al.

TRANSPLANTATION (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

Mortality Related to Nonalcoholic Fatty Liver Disease Is Increasing in the United States

James M. Paik et al.

HEPATOLOGY COMMUNICATIONS (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options

Amalia Gastaldelli et al.

JHEP REPORTS (2019)

添加到收藏夹

Review Endocrinology & Metabolism

Insulin-like growth factor-1 and non-alcoholic fatty liver disease: a systemic review and meta-analysis

Yang Yao et al.

ENDOCRINE (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

Naga Chalasani et al.

HEPATOLOGY (2018)

添加到收藏夹

Review Gastroenterology & Hepatology

Racial and Ethnic Disparities in Nonalcoholic Fatty Liver Disease Prevalence, Severity, and Outcomes in the United States: A Systematic Review and Meta-analysis

Nicole E. Rich et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2018)

添加到收藏夹

Article Endocrinology & Metabolism

Nonalcoholic Fatty Liver Disease and Risk of Incident Type 2 Diabetes: A Meta-analysis

Alessandro Mantovani et al.

DIABETES CARE (2018)

添加到收藏夹

Article Physiology

Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease

Jack A. Sargeant et al.

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2018)

添加到收藏夹

Review Gastroenterology & Hepatology

Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis

Rohan Khera et al.

GASTROENTEROLOGY (2018)

添加到收藏夹

Review Endocrinology & Metabolism

Post-Liver Transplantation Diabetes Mellitus: A Review of Relevance and Approach to Treatment

Maria J. Pelaez-Jaramillo et al.

DIABETES THERAPY (2018)

添加到收藏夹

Review Endocrinology & Metabolism

Post-Liver Transplantation Diabetes Mellitus: A Review of Relevance and Approach to Treatment

Maria J. Pelaez-Jaramillo et al.

DIABETES THERAPY (2018)

添加到收藏夹

Review Gastroenterology & Hepatology

Association between diastolic cardiac dysfunction and nonalcoholic fatty liver disease: A systematic review and meta-analysis

Karn Wijarnpreecha et al.

DIGESTIVE AND LIVER DISEASE (2018)

添加到收藏夹

Review Endocrinology & Metabolism

The effect of exercise training on intrahepatic triglyceride and hepatic insulin sensitivity: a systematic review and meta-analysis

J. A. Sargeant et al.

OBESITY REVIEWS (2018)

添加到收藏夹

Review Endocrinology & Metabolism

Association Between Primary Hypothyroidism and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Alessandro Mantovani et al.

THYROID (2018)

添加到收藏夹

Article Respiratory System

Relationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea National Health and Nutrition Examination Survey, 2007-2010

Sung Woo Moon et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)

添加到收藏夹

Article Gastroenterology & Hepatology

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis

Stuart McPherson et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

添加到收藏夹

Review Gastroenterology & Hepatology

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries

Paul Y. Kwo et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

Leon A. Adams et al.

GUT (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

Liver Fibrosis Scores Predict Liver Disease Mortality in the United States Population

Aynur Unalp-Arida et al.

HEPATOLOGY (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

Aerobic vs. resistance exercise in non-alcoholic fatty liver disease: A systematic review

Ryuki Hashida et al.

JOURNAL OF HEPATOLOGY (2017)

添加到收藏夹

Article Genetics & Heredity

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci

Stefan Stender et al.

NATURE GENETICS (2017)

添加到收藏夹

Article Medicine, General & Internal

Bariatric Surgery versus Intensive Medical Therapy for Diabetes-5-Year Outcomes

Philip R. Schauer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

添加到收藏夹

Article Medicine, General & Internal

Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis A Meta-analysis

Giovanni Musso et al.

JAMA INTERNAL MEDICINE (2017)

添加到收藏夹

Review Endocrinology & Metabolism

Pioglitazone and the Risk of Bladder Cancer: A Meta-Analysis

Elena Filipova et al.

DIABETES THERAPY (2017)

添加到收藏夹

Review Endocrinology & Metabolism

Pioglitazone and the Risk of Bladder Cancer: A Meta-Analysis

Elena Filipova et al.

DIABETES THERAPY (2017)

添加到收藏夹

Article Medicine, General & Internal

Plasma thyroid hormone concentration is associated with hepatic triglyceride content in patients with type 2 diabetes

Fernando Bril et al.

JOURNAL OF INVESTIGATIVE MEDICINE (2016)

添加到收藏夹

Article Medicine, General & Internal

Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus A Randomized Trial

Kenneth Cusi et al.

ANNALS OF INTERNAL MEDICINE (2016)

添加到收藏夹

Article Endocrinology & Metabolism

Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease

Silvio E. Inzucchi et al.

DIABETES CARE (2016)

添加到收藏夹

Article Endocrinology & Metabolism

Metabolic Impact of Nonalcoholic Steatohepatitis in Obese Patients With Type 2 Diabetes

Romina Lomonaco et al.

DIABETES CARE (2016)

添加到收藏夹

Article Endocrinology & Metabolism

Different effects of basal insulin peglispro and insulin glargine on liver enzymes and liver fat content in patients with type 1 and type 2 diabetes

K. Cusi et al.

DIABETES OBESITY & METABOLISM (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

Giulio Marchesini et al.

JOURNAL OF HEPATOLOGY (2016)

添加到收藏夹

Article Medicine, General & Internal

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

Matthew James Armstrong et al.

LANCET (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

Fibrosis Stage Is the Strongest Predictor for Disease-Specific Mortality in NAFLD After Up to 33 Years of Follow-Up

Mattias Ekstedt et al.

HEPATOLOGY (2015)

添加到收藏夹

Article Endocrinology & Metabolism

High Prevalence of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus and Normal Plasma Aminotransferase Levels

Paola Portillo-Sanchez et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)

添加到收藏夹

Article Gastroenterology & Hepatology

Clinical value of liver ultrasound for the diagnosis of nonalcoholic fatty liver disease in overweight and obese patients

Fernando Bril et al.

LIVER INTERNATIONAL (2015)

添加到收藏夹

Article Gastroenterology & Hepatology

The Role of Liver Fat and Insulin Resistance as Determinants of Plasma Aminotransferase Elevation in Nonalcoholic Fatty Liver Disease

Maryann Maximos et al.

HEPATOLOGY (2015)

添加到收藏夹

Article Gastroenterology & Hepatology

The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease

Marno C. Ryan et al.

JOURNAL OF HEPATOLOGY (2013)

添加到收藏夹

Review Gastroenterology & Hepatology

Long-term management of the successful adult liver transplant: 2012 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation

Michael R. Lucey et al.

LIVER TRANSPLANTATION (2013)

添加到收藏夹

Article Gastroenterology & Hepatology

Role of Ethnicity in Overweight and Obese Patients with Nonalcoholic Steatohepatitis

Romina Lomonaco et al.

HEPATOLOGY (2011)

添加到收藏夹

Article Medicine, General & Internal

Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance

Ralph A. DeFronzo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

添加到收藏夹

Article Surgery

Evolution of Causes and Risk Factors for Mortality Post-Liver Transplant: Results of the NIDDK Long-Term Follow-Up Study

K. D. S. Watt et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2010)

添加到收藏夹

Article Gastroenterology & Hepatology

Randomized Controlled Trial Testing the Effects of Weight Loss on Nonalcoholic Steatohepatitis

Kittichai Promrat et al.

HEPATOLOGY (2010)

添加到收藏夹

Article Medicine, General & Internal

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis.

Arun J. Sanyal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

添加到收藏夹

Article Immunology

Posttransplant Hyperglycemia is Associated With Increased Risk of Liver Allograft Rejection

Amisha Wallia et al.

TRANSPLANTATION (2010)

添加到收藏夹

Editorial Material Urology & Nephrology

Foreword

Kai-Uwe Eckardt et al.

KIDNEY INTERNATIONAL (2009)

添加到收藏夹

Article Gastroenterology & Hepatology

Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis

Guruprasad P. Aithal et al.

GASTROENTEROLOGY (2008)

添加到收藏夹

Article Gastroenterology & Hepatology

Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects

Amalia Gastaldelli et al.

GASTROENTEROLOGY (2007)

添加到收藏夹

Article Endocrinology & Metabolism

Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes

Leena Juurinen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)

添加到收藏夹

Article Medicine, General & Internal

A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis

Renata Belfort et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.