Activated carbon fibers supported palladium as efficient and easy-separable catalyst for carbonylative cyclization of o-alkynylphenols with nitroarenes: Facile construction of benzofuran-3-carboxamides

Heterogeneous catalytic processes have a number of advantages over conventional chemical synthesis, such as lower catalyst loading and easier catalyst recyclability. Activated carbon fibers (ACFs) can be readily prepared and used in most organically reactive environments due to its excellent high temperature resistance and chemical stability. Herein, a heterogeneous activated carbon fibers supported palladium (Pd/ACFs) catalyzed carbonylative cyclization of o-alkynylphenols with nitroarenes has been developed for the rapid construction of 3-carbonyl-benzo[b]furan scaffolds. By employing nitroarenes as the nitrogen source, Mo(CO)(6) as both the CO surrogate and the reductant, the reaction afforded a variety of 3-carbonyl-benzo[b]furan derivatives in good to excellent yields. (C) 2022 Elsevier Inc. All rights reserved.

Automated summary

A heterogeneous catalytic reaction using activated carbon fibers supported palladium catalyst has been developed for the rapid construction of 3-carbonyl-benzo[b]furan scaffolds. The reaction exhibits good to excellent yields with a variety of substrates.