The predictive value of C-reactive protein to albumin ratio for ascending aort progression in patients with ascending aortic diameter of 40-50 mm

We aimed to investigate the ability of the C-reactive protein-to-albumin ratio (CAR) to predict ascending aorta progression in patients with 40-50 mm diameter of ascending aortic dilatation. A total of 182 diagnosed patients with ascending aortic diameters of 40-50 mm were enrolled in this study. The study population was divided into tertiles based on yearly ascending aortic growth rate values. Group I (n = 137) was defined as a value in the lower 2 tertiles (ascending aorta growth <= 1.00 mm/year), and group II (n = 45) was defined as a value in the third tertile (ascending aorta growth > 1.00 mm/year). Hypertension, chronic obstructive pulmonary disease, positive family history, and CAR were found to be independent risk factors for ascending aorta growth > 1.00 mm/year. The area under the ROC curve (AUC) of CAR was 0.771(95% CI 0.689-0.854) for predicting ascending aorta growth > 1.00 mm/year. In patients with 40-50 mm ascending aneurysms, CAR may be useful to predict ascending aorta progression.

Automated summary

This study investigated the predictive ability of the C-reactive protein-to-albumin ratio (CAR) for ascending aorta progression in patients with 40-50 mm diameter of ascending aortic dilatation. Hypertension, chronic obstructive pulmonary disease, positive family history, and CAR were identified as independent risk factors for ascending aorta growth > 1.00 mm/year. The AUC of CAR for predicting ascending aorta growth > 1.00 mm/year was 0.771(95% CI 0.689-0.854). CAR may be useful for predicting ascending aorta progression in patients with 40-50 mm ascending aneurysms.