期刊
JOURNAL OF INNATE IMMUNITY
卷 9, 期 2, 页码 111-125出版社
KARGER
DOI: 10.1159/000453397
关键词
Host defense; Immune response; Neutrophils; Pattern recognition receptors; Phagocytosis; Toll-like receptor; Innate Immunity; Myeloid-derived suppressor cells; Innate lymphoid cells; Macrophages
类别
资金
- DFG Emmy Noether program
- DFG priority program
Innate immunity is a rapidly evolving field with novel cell types and molecular pathways being discovered and paradigms changing continuously. Innate and adaptive immune responses are traditionally viewed as separate from each other, but emerging evidence suggests that they overlap and mutually interact. Recently discovered cell types, particularly innate lymphoid cells and myeloid-derived suppressor cells, are gaining increasing attention. Here, we summarize and highlight current concepts in the field, focusing on innate immune cells as well as the inflammasome and DNA sensing which appear to be critical for the activation and orchestration of innate immunity, and may provide novel therapeutic opportunities for treating autoimmune, auto-inflammatory, and infectious diseases. (C) 2016 S. Karger AG, Basel
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据