期刊
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
卷 26, 期 8, 页码 710-719出版社
INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D)
DOI: 10.5588/ijtld.22.0006
关键词
SARS-CoV-2; coronavirus; pandemic; mortality
资金
- Brazilian Ministry of Science, Technology and Innovation, Conselho Nacional de Desenvolvimento e Pesquisa [CNPq-441048/20200]
- Republic of South Africa, Department of Science and Innovation (DSI)
- Republic of South Africa, South African Medical Research Council (SAMRC) under the BRICS JAF [2020/101]
- Government of India, Ministry of Science & Technology, Department of Biotechnology
- FSBI Russian Foundation for Basic Research [20515-80006]
The COVID-19 pandemic has negatively affected tuberculosis services, leading to setbacks in mortality and detection. Tuberculosis may increase COVID-19 fatality and incidence. However, the pandemic has also provided opportunities for improving tuberculosis care.
Together, SARS-CoV-2 and M. tuberculosis have killed approximately 5.7 million people worldwide over the past 2 years. The COVID-19 pandemic, and the non -pharmaceutical interventions to mitigate COVID-19 transmission (including social distancing regulations, partial lockdowns and quarantines), have disrupted healthcare services and led to a reallocation of resources to COVID-19 care. There has also been a tragic loss of healthcare workers who succumbed to the disease. This has had consequences for TB services, and the fear of contracting COVID-19 may also have contributed to reduced access to TB services. Altogether, this is projected to have resulted in a 5-year setback in terms of mortality from TB and a 9-year setback in terms of TB detection. In addition, past and present TB disease has been reported to increase both COVID-19 fatality and incidence. Similarly, COVID-19 may adversely affect TB outcomes. From a more positive perspective, the pandemic has also created opportunities to improve TB care. In this review, we highlight similarities and differences between these two infectious diseases, describe gaps in our knowledge and discuss solutions and priorities for future research.
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