期刊
JOURNAL OF INFECTIOUS DISEASES
卷 213, 期 12, 页码 1893-1896出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiw063
关键词
oral HPV; young adults; STD clinic; sex; epidemiology
资金
- Merck Sharp and Dohme [36205]
- Oral Cancer Foundation
Oral human papillomavirus genotype 16 (HPV16) infection causes oropharyngeal squamous cell carcinoma (SCC), and the prevalence of oropharyngeal SCC is higher among men than women in the United States. In a cohort study of oral HPV infection among 409 individuals aged 18-25 years, the risk among men but not among women significantly increased as the number of recent (ie, within the prior 3 months) oral sex partners increased (P-interaction = .05). In contrast, the risk among women but not among men significantly decreased as the lifetime number of vaginal sex partners increased (P-interaction = .037). Men were also significantly less likely than women to clear oral HPV infection. Our data contribute to understanding sex differences in risk for HPV-positive oropharyngeal SCC.
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