☆ 4.7 Article

An Axis between the Long Non-Coding RNA HOXA11-AS and NQOs Enhances Metastatic Ability in Oral Squamous Cell Carcinoma

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Linoleic Acid Upregulates Microrna-494 to Induce Quiescence in Colorectal Cancer

Ruiko Ogata et al.

Summary: Research has shown that long-term treatment of cancer cells with linoleic acid induces a dormant state through a mechanism involving upregulation of miR-494. The expression of miR-494 is influenced by mitochondrial oxidative stress, playing a crucial role in dormant cancer cells.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Oncology

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 A Systematic Analysis for the Global Burden of Disease Study 2019

Jonathan M. Kocarnik et al.

Summary: The global burden of cancer is substantial and growing, with differences in burden based on Sociodemographic Index (SDI). The largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles from 2010 to 2019.

JAMA ONCOLOGY (2022)

添加到收藏夹

Article Immunology

Dihydronicotinamide Riboside Is a Potent NAD+ Precursor Promoting a Pro-Inflammatory Phenotype in Macrophages

Claudia C. S. Chini et al.

Summary: Nicotinamide adenine dinucleotide (NAD) metabolism plays a crucial role in immune function regulation, but the complete understanding of how NAD and its metabolites, precursors, and enzymes work together in immune function and inflammatory diseases is still lacking. This study found that supplementation of NAD precursor NRH significantly increased NAD(+) levels in macrophages and activated a pro-inflammatory phenotype, inducing the expression of multiple cytokines, chemokines, and enzymes. Furthermore, NRH enhanced the effect of lipopolysaccharide on macrophage activation and cytokine gene expression.

FRONTIERS IN IMMUNOLOGY (2022)

添加到收藏夹

Article Nutrition & Dietetics

Nicotinamide Riboside and Dihydronicotinic Acid Riboside Synergistically Increase Intracellular NAD+ by Generating Dihydronicotinamide Riboside

Eleonora Ciarlo et al.

Summary: This study demonstrates for the first time that dihydronicotinic acid riboside (NARH) can act as a NAD(+) precursor in mammalian cells, and how different NAD(+) precursors can interact and influence each other when co-administered.

NUTRIENTS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

LncRNA HOXA11-AS aggravates the keloid formation by targeting miR-148b-3p/IGFBP5 axis

Juan Wang et al.

Summary: HOXA11-AS promotes keloid progression through the miR-148b-3p/IGFBP5 axis, inhibiting apoptosis and increasing cell proliferation and migration in keloid fibroblasts.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Current Trends and Future Prospects of Molecular Targeted Therapy in Head and Neck Squamous Cell Carcinoma

Naoya Kitamura et al.

Summary: In recent years, drug therapy for head and neck squamous cell carcinoma (HNSCC) has made rapid progress, with a focus on molecular targeted therapy and immune checkpoint inhibitors in addition to traditional cytotoxic anti-cancer agents. While the importance of anti-cancer drug therapy continues to increase, current trends and future prospects of molecular targeted therapy in HNSCC are being explored in clinical trials.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Cell Biology

Gene regulation by long non-coding RNAs and its biological functions

Luisa Statello et al.

Summary: Recent studies have shed new light on the biogenesis and functions of long non-coding RNAs (lncRNAs), showcasing their diverse roles in gene regulation and signaling pathways, particularly in the contexts of neuronal disorders, immune responses, and cancer. The discovery of unique biogenesis pathways and subcellular localizations of lncRNAs has opened up potential therapeutic avenues for targeting lncRNAs in various biological and pathophysiological conditions.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

添加到收藏夹

Article Oncology

LncRNA SBF2-AS1 Promotes Diffuse Large B-Cell Lymphoma Growth by Regulating FGFR2 via Sponging miR-494-3p

Dong-Wei Fu et al.

Summary: This study revealed that SBF2-AS1 promoted the growth of DLBCL through the miR-494-3p/FGFR2 axis, and this mechanism was confirmed in in vivo tumorigenesis experiments.

CANCER MANAGEMENT AND RESEARCH (2021)

添加到收藏夹

Article Oncology

NQO1 as a Marker of Chemosensitivity and Prognosis for Colorectal Liver Metastasis

Yuki Hirose et al.

Summary: This study showed that NQO1-positive expression in tumor cells of colorectal liver metastasis (CRLM) was associated with worse overall survival after hepatectomy, indicating it as an adverse prognostic factor. Additionally, patients with loss of NQO1 expression in non-neoplastic epithelial cells of the bile ducts had a better response to preoperative chemotherapy for CRLM.

ANTICANCER RESEARCH (2021)

添加到收藏夹

Article Cell Biology

Phosphoglycerate kinase 1 silencing by a novel microRNA microRNA-4523 protects human osteoblasts from dexamethasone through activation of Nrf2 signaling cascade

Jin-qian Liang et al.

Summary: miR-4523 protects human osteoblasts from dexamethasone-induced oxidative injury and cell death by silencing PGK1 and activating the Nrf2 signaling cascade, indicating a potential therapeutic target for osteoporosis treatment.

CELL DEATH & DISEASE (2021)

添加到收藏夹

Article Oncology

Systematic Analysis and Identification of Dysregulated Panel lncRNAs Contributing to Poor Prognosis in Head-Neck Cancer

Shang-Ju Tang et al.

Summary: Head and neck cancer (HNC) is one of the most prevalent cancers worldwide, and dysregulation of lncRNAs may disrupt biological pathways in HNC. This study identified a panel of 31 lncRNAs associated with HNC, which could predict patient prognosis.

FRONTIERS IN ONCOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress

Y. Li et al.

Summary: Dioscin can alleviate MTX-induced hepatorenal damages by regulating oxidative stress mediated by miR-145-5p. This natural product may be considered as an effective drug for treating this disorder in the future.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

添加到收藏夹

Article Neurosciences

Using Monozygotic Twins to Dissect Common Genes in Posttraumatic Stress Disorder and Migraine

Charlotte K. Bainomugisa et al.

Summary: Epigenetic mechanisms were associated with genes involved in PTSD and migraine. Using a monozygotic twin disease discordant study design, researchers identified candidate genes associated with PTSD and novel CpG sites associated with PTSD within/near specific genes. Furthermore, genes associated with both PTSD and migraine were enriched in specific signaling pathways, suggesting common genetic factors and pathways may contribute to the comorbidity between PTSD and migraine.

FRONTIERS IN NEUROSCIENCE (2021)

添加到收藏夹

Review Oncology

Long Non-Coding RNAs in Diagnosis, Treatment, Prognosis, and Progression of Glioma: A State-of-the-Art Review

Sara Momtazmanesh et al.

Summary: Glioma, the most common malignant central nervous system tumor, presents challenges due to incomplete understanding of molecular pathways in tumor progression. Long non-coding RNAs (lncRNAs) are implicated in various stages of glioma development and hold potential for diagnostic and therapeutic applications. Evaluating lncRNAs' roles in tumor progression, molecular pathways, and clinical relevance is essential for advancing novel therapeutic strategies.

FRONTIERS IN ONCOLOGY (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

NAD+ metabolism, stemness, the immune response, and cancer

Lola E. Navas et al.

Summary: NAD(+) plays important roles in redox metabolism, aging, longevity, immune system, and DNA repair. Dysregulation of NAD(+) levels is associated with metabolic diseases and aging-related diseases. NAMPT is the key enzyme recovering NAD from nicotinamide. The roles of NAD(+) and NAMPT in cancer metabolism, immune system, stemness, aging, and cancer are significant.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

添加到收藏夹

Article Neurosciences

microRNA-592 blockade inhibits oxidative stress injury in Alzheimer's disease astrocytes via the KIAA0319-mediated Keap1/Nrf2/ARE signaling pathway

Guo-De Wu et al.

EXPERIMENTAL NEUROLOGY (2020)

添加到收藏夹

Review Oncology

Beyond Energy Metabolism: Exploiting the Additional Roles of NAMPT for Cancer Therapy

Christine M. Heske

FRONTIERS IN ONCOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

Ravirajsinh N. Jadeja et al.

REDOX BIOLOGY (2020)

添加到收藏夹

Review Oncology

Recent advances in unraveling the molecular mechanisms and functions of HOXA11-AS in human cancers and other diseases

Cheng Wei et al.

ONCOLOGY REPORTS (2020)

添加到收藏夹

Article Cell Biology

被撤回的出版物: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p (Retracted article. See vol. 14, 2023)

Wei Huang et al.

CELL DEATH & DISEASE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas

Chie Nakashima et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Anti-Stem Cell Property of Pterostilbene in Gastrointestinal Cancer Cells

Shiori Mori et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Oncology

HOX cluster-embedded antisense long non-coding RNAs in lung cancer

Lianlian Li et al.

CANCER LETTERS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo

Yue Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1

Xuerong Zhao et al.

PHARMACOLOGICAL RESEARCH (2019)

添加到收藏夹

Article Oncology

Expression of cytosolic malic enzyme (ME1) is associated with disease progression in human oral squamous cell carcinoma

Chie Nakashima et al.

CANCER SCIENCE (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress

Lisha Zhao et al.

REDOX BIOLOGY (2018)

添加到收藏夹

Review Cell Biology

The role of the long non-coding RNA HOXA11-AS in promoting proliferation and metastasis of malignant tumors

Shounan Lu et al.

CELL BIOLOGY INTERNATIONAL (2018)

添加到收藏夹

Article Medicine, Research & Experimental

被撤回的出版物: MicroRNA-494 inhibition alleviates acute lung injury through Nrf2 signaling pathway via NQO1 in sepsis-associated acute respiratory distress syndrome (Retracted article. See vol. 325, 2023)

Yun Ling et al.

LIFE SCIENCES (2018)

添加到收藏夹

Article Biotechnology & Applied Microbiology

HOXA11-AS: a novel regulator in human cancer proliferation and metastasis

Jiang-yang Xue et al.

ONCOTARGETS AND THERAPY (2018)

添加到收藏夹

Article Oncology

NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis

Antonio Lucena-Cacace et al.

ONCOTARGET (2017)

添加到收藏夹

Review Oncology

Functional and therapeutic significance of EZH2 in urological cancers

Xiaobing Liu et al.

ONCOTARGET (2017)

添加到收藏夹

Article Oncology

Genome-wide analysis of long noncoding RNA (lncRNA) expression in colorectal cancer tissues from patients with liver metastasis

Dong Chen et al.

CANCER MEDICINE (2016)

添加到收藏夹

Article Cell Biology

MicroRNA-200a controls Nrf2 activation by target Keap1 in hepatic stellate cell proliferation and fibrosis

Jing-Jing Yang et al.

CELLULAR SIGNALLING (2014)

添加到收藏夹

Article Medicine, Research & Experimental

Perioperative Survival of Elderly Head and Neck Squamous Cell Carcinoma Patients

William A. Stokes et al.

LARYNGOSCOPE (2014)

添加到收藏夹

Review Multidisciplinary Sciences

The multilayered complexity of ceRNA crosstalk and competition

Yvonne Tay et al.

NATURE (2014)

添加到收藏夹

Article Chemistry, Medicinal

Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

David M. Goldstein et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

添加到收藏夹

Article Medicine, General & Internal

Head and Neck Squamous Cell Carcinoma: New Translational Therapies

Anthony Prince et al.

MOUNT SINAI JOURNAL OF MEDICINE (2010)

添加到收藏夹

Article Cell Biology

Reg IV enhances peritoneal metastasis in gastric carcinomas

H. Kuniyasu et al.

CELL PROLIFERATION (2009)

添加到收藏夹

Article Oncology

Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis

Alessandro Provenzani et al.

CARCINOGENESIS (2006)

添加到收藏夹

Article Biochemistry & Molecular Biology

Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity

DJ Long et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

添加到收藏夹

Article Oncology

Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer

H Kuniyasu et al.

JOURNAL OF PATHOLOGY (2002)

添加到收藏夹

Review Multidisciplinary Sciences

Translating the histone code

T Jenuwein et al.

SCIENCE (2001)

添加到收藏夹

Article Biochemistry & Molecular Biology

NRH:quinone oxidoreductase2 (NQO2)

DJ Long et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.