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Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2022)
SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in an Arf6-dependent manner
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Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway
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BIOSCIENCE REPORTS (2021)
Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
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Cyclophilin A is a factor of antitumor defense in the early stages of tumor development
Anastasiia Kalinina et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
CypA: A Potential Target of Tumor Radiotherapy and/or Chemotherapy
Man-Yu Chu et al.
CURRENT MEDICINAL CHEMISTRY (2021)
CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma
Minami Sakamoto et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
Sonia Simon Serrano et al.
CANCERS (2021)
FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers
Huizhe Xu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
CD147 Promotes Cell Small Extracellular Vesicles Release during Colon Cancer Stem Cells Differentiation and Triggers Cellular Changes in Recipient Cells
Donatella Lucchetti et al.
CANCERS (2020)
Characterization of Tailoring Steps of Nargenicin A1 Biosynthesis Reveals a Novel Analogue with Anticancer Activities
Dipesh Dhakal et al.
ACS CHEMICAL BIOLOGY (2020)
CD147 Expression Is Associated with Tumor Proliferation in Bladder Cancer via GSDMD
Junming Peng et al.
BIOMED RESEARCH INTERNATIONAL (2020)
FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
Giorgio Ramadori et al.
CELL REPORTS (2020)
Cyclophilin A Inhibitor Debio-025 Targets Crk, Reduces Metastasis, and Induces Tumor Immunogenicity in Breast Cancer
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MOLECULAR CANCER RESEARCH (2020)
Downregulation of CyclophilinA/CD147 Axis Induces Cell Apoptosis and Inhibits Glioma Aggressiveness
Shengchao Xu et al.
BIOMED RESEARCH INTERNATIONAL (2020)
Novel Nargenicin A1 Analog Inhibits Angiogenesis by Downregulating the Endothelial VEGF/VEGFR2 Signaling and Tumoral HIF-1α/VEGF Pathway
Jang Mi Han et al.
BIOMEDICINES (2020)
Detachment Activated CyPA/CD147 Induces Cancer Stem Cell Potential in Non-stem Breast Cancer Cells
Yao Meng et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
MiR-890 inhibits proliferation and invasion and induces apoptosis in triple-negative breast cancer cells by targeting CD147
Cheng Wang et al.
BMC CANCER (2019)
CD147 Is a Promising Target of Tumor Progression and a Prognostic Biomarker
Alexandra Landras et al.
CANCERS (2019)
The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells
Isabella Spinello et al.
HAEMATOLOGICA (2019)
Cyclophilin A promotes non-small cell lung cancer metastasis via p38 MAPK
Yinan Guo et al.
THORACIC CANCER (2018)
Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland
Sonja E. Volker et al.
CANCER RESEARCH (2018)
The combination of FK506 and an anti-CD147 mAb exerts potential therapeutic effects on a mouse model of collagen-induced arthritis
Jing Luan et al.
MOLECULAR IMMUNOLOGY (2018)
Melittin inhibits the invasion of MCF-7 cells by downregulating CD147 and MMP-9 expression
Jianjun Wang et al.
ONCOLOGY LETTERS (2017)
Cancer stem cells revisited
Eduard Batlle et al.
NATURE MEDICINE (2017)
The effects and mechanisms of SLC34A2 on maintaining stem cell-like phenotypes in CD147+ breast cancer stem cells
Yonggang Lv et al.
TUMOR BIOLOGY (2017)
RNA interference-mediated gene silencing of cyclophilin A enhances the radiosensitivity of PAa human lung adenocarcinoma cells in vitro
Xin Jiang et al.
ONCOLOGY LETTERS (2017)
Repressing CD147 is a novel therapeutic strategy for malignant melanoma
Xing Hu et al.
ONCOTARGET (2017)
UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
Darshan S. Chandrashekar et al.
NEOPLASIA (2017)
Cyclophilin A Maintains Glioma-Initiating Cell Stemness by Regulating Wnt/β-Catenin Signaling
Guangzhi Wang et al.
CLINICAL CANCER RESEARCH (2017)
TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
Taiwen Li et al.
CANCER RESEARCH (2017)
Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells
Silvia Lemma et al.
PLOS ONE (2016)
CD147 knockdown improves the antitumor efficacy of trastuzumab in HER2-positive breast cancer cells
Lijuan Xiong et al.
ONCOTARGET (2016)
A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells
Zhi-guang Fu et al.
ONCOTARGET (2016)
CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis
Xiaoyan Xin et al.
SCIENTIFIC REPORTS (2016)
Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy
Wanyin Chen et al.
STEM CELLS INTERNATIONAL (2016)
Soluble extracellular matrix metalloproteinase inducer (EMMPRIN, EMN) regulates cancer-related cellular functions by homotypic interactions with surface CD147
Nadine Knutti et al.
FEBS JOURNAL (2015)
Inhibition of CD 147 expression by RNA interference reduces proliferation, invasion and increases chemosensitivity in cancer stem cell-like HT-29 cells
Jie Chen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis
Li-sen Qin et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
Translational Horizons in the Tumor Microenvironment: Harnessing Breakthroughs and Targeting Cures
Yu Sun
MEDICINAL RESEARCH REVIEWS (2015)
Cancer Stem Cells: The Promise and the Potential
Jaffer A. Ajani et al.
SEMINARS IN ONCOLOGY (2015)
HAb18G/CD147 Promotes Radioresistance in Hepatocellular Carcinoma Cells: A Potential Role for Integrin β1 Signaling
Jiao Wu et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast
Alessandra Rustighi et al.
EMBO MOLECULAR MEDICINE (2014)
Randomized Trial of [131I] Metuximab in Treatment of Hepatocellular Carcinoma After Percutaneous Radiofrequency Ablation
Huijie Bian et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)
Expression of Cyclophilin A in Gastric Adenocarcinoma Patients and Its Inverse Association with Local Relapses and Distant Metastasis
Evgeniya S. Grigoryeva et al.
PATHOLOGY & ONCOLOGY RESEARCH (2014)
Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling
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PLOS ONE (2014)
Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study
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BMJ-BRITISH MEDICAL JOURNAL (2014)
A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells
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CANCER LETTERS (2013)
HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
Ling Li et al.
CLINICAL CANCER RESEARCH (2013)
Expression and prognostic relevance of Cyclophilin A and matrix metalloproteinase 9 in esophageal squamous cell carcinoma
Yi Li et al.
DIAGNOSTIC PATHOLOGY (2013)
Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular Carcinoma
Jinhwa Lee
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY (2013)
Proteomic analysis reveals that CD147/EMMPRIN confers chemoresistance in cancer stem cell-like cells
Min Jueng Kang et al.
PROTEOMICS (2013)
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
Jianjiong Gao et al.
SCIENCE SIGNALING (2013)
Cyclophilin A: a key player for human disease
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CELL DEATH & DISEASE (2013)
Cancer Stem Cells: Current Status and Evolving Complexities
Jane E. Visvader et al.
CELL STEM CELL (2012)
Cyclosporine A inhibits breast cancer cell growth by downregulating the expression of pyruvate kinase subtype M2
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INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2012)
In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147
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PLOS ONE (2012)
Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-kappa B
Shan Sun et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma
Sumalee Obchoei et al.
MOLECULAR CANCER (2011)
Oxidative Stress in Neurodegenerative Diseases: Mechanisms and Therapeutic Perspectives
Ailton Melo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2011)
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics
V. Yurchenko et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
CD147 and VEGF Co-expression Predicts Prognosis in Patients with Acute Myeloid Leukemia
Jufang Fu et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2010)
RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletion
Ye-Hong Kuang et al.
CANCER LETTERS (2009)
Solution Characterization of the Extracellular Region of CD147 and Its Interaction with Its Enzyme Ligand Cyclophilin A
Jennifer Schlegel et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
Anna Dubrovska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation
Kimio Satoh et al.
CIRCULATION (2008)
Crystal structure of HAb18g/CD147 - Implications for immunoglobulin superfamily homophilic adhesion
Xiao-Ling Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Proteomics Identification of Cyclophilin A as a Potential Prognostic Factor and Therapeutic Target in Endometrial Carcinoma
Zhengyu Li et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
Oligo-microarray analysis reveals the role of cyclophilin A in drug resistance
Shuai Chen et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)
Cyclophilin A is upregulated in small cell lung cancer and activates ERK1/2 signal
Huirong Yang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Overexpressed cyclophilin A in cancer cells renders resistance to hypoxia- and cisplatin-induced cell death
Kyu Jin Choi et al.
CANCER RESEARCH (2007)
A Randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation
Jing Xu et al.
HEPATOLOGY (2007)
A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma
Xiang Chen et al.
CANCER RESEARCH (2006)
Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147
M Li et al.
CANCER (2006)
The regulation of exosome secretion: a novel function of the p53 protein
Xin Yu et al.
CANCER RESEARCH (2006)
Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells
J Suzuki et al.
CIRCULATION RESEARCH (2006)
Stable RNA interference-mediated suppression of Cyclophilin A diminishes non-small-cell lung tumor growth in vivo
BA Howard et al.
CANCER RESEARCH (2005)
Structure of human cyclophilin a in complex with the novel immunosuppressant sanglifehrin a at 1.6 Å resolution
J Kallen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine
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JOURNAL OF IMMUNOLOGY (2005)
Roles of the multifunctional glycoprotein, emmprin (basigin; CD 147), in tumour progression
L Yan et al.
THROMBOSIS AND HAEMOSTASIS (2005)
Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes
Y Seko et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
PI3K/Akt and apoptosis: size matters
TF Franke et al.
ONCOGENE (2003)
Active site residues of cyclophilin A are crucial for its signaling activity via CD147
V Yurchenko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A
DA Bosco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Stem cells, cancer, and cancer stem cells
T Reya et al.
NATURE (2001)
Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action
G Zenke et al.
JOURNAL OF IMMUNOLOGY (2001)
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A
T Pushkarsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Expression of Basigin in human fetal, infantile and adult skin and in basal cell carcinoma
X Chen et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2001)
Cyclophilin A is a secreted growth factor induced by oxidative stress
ZG Jin et al.
CIRCULATION RESEARCH (2000)
Homo-oligomer formation by basigin, an immunoglobulin superfamily member, via its N-terminal immunoglobulin domain
S Yoshida et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Enzymes that catalyse the restructuring of proteins
C Schiene et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2000)
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