相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Identification of Altered Blood MicroRNAs and Plasma Proteins in a Rat Model of Parkinson's Disease
Sanjeev Kumar Yadav et al.
MOLECULAR NEUROBIOLOGY (2022)
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS
Paul J. Hop et al.
SCIENCE TRANSLATIONAL MEDICINE (2022)
Co-Expression Analysis of microRNAs and Proteins in Brain of Alzheimer's Disease Patients
Callum N. Watson et al.
CELLS (2022)
Genome-Wide Methylation Profiling in the Thalamus of Scrapie Sheep
Adelaida Hernaiz et al.
FRONTIERS IN VETERINARY SCIENCE (2022)
Two distinct skeletal muscle microRNA signatures revealing the complex mechanism of sporadic ALS
Evrim Aksu-Menges et al.
ACTA NEUROLOGICA BELGICA (2022)
Insights into the identification of a molecular signature for amyotrophic lateral sclerosis exploiting integrated microRNA profiling of iPSC-derived motor neurons and exosomes
Mafalda Rizzuti et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2022)
Interactions of amyloid coaggregates with biomolecules and its relevance to neurodegeneration
Kazuma Murakami et al.
FASEB JOURNAL (2022)
DNA methylation analysis of archival lymphoreticular tissues in Creutzfeldt-Jakob disease
Fernando Guntoro et al.
ACTA NEUROPATHOLOGICA (2022)
CRISPR/dCas9-Dnmt3a-mediated targeted DNA methylation of APP rescues brain pathology in a mouse model of Alzheimer's disease
Hanseul Park et al.
TRANSLATIONAL NEURODEGENERATION (2022)
Interaction of Prion Peptides with DNA Structures
Anshula Tandon et al.
ACS OMEGA (2022)
Profiling of Serum Exosome MiRNA Reveals the Potential of a MiRNA Panel as Diagnostic Biomarker for Alzheimer's Disease
Zhiwu Dong et al.
MOLECULAR NEUROBIOLOGY (2021)
Small Non-coding RNAs Are Dysregulated in Huntington's Disease Transgenic Mice Independently of the Therapeutic Effects of an Environmental Intervention
Celine Dubois et al.
MOLECULAR NEUROBIOLOGY (2021)
Association of peripheral blood DNA methylation level with Alzheimer's disease progression
Qingqin S. Li et al.
CLINICAL EPIGENETICS (2021)
Extracellular Vesicles in Serum and Central Nervous System Tissues Contain microRNA Signatures in Sporadic Amyotrophic Lateral Sclerosis
Ting-wen Lo et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2021)
Profiling of Differentially Expressed MicroRNAs in Saliva of Parkinson's Disease Patients
Yanyan Jiang et al.
FRONTIERS IN NEUROLOGY (2021)
DNA Methylation and Expression Profiles of Whole Blood in Parkinson's Disease
Adrienne R. Henderson et al.
FRONTIERS IN GENETICS (2021)
Protein Binding Partners of Dysregulated miRNAs in Parkinson's Disease Serum
Wolfgang P. Ruf et al.
CELLS (2021)
Differential expression of gut miRNAs in idiopathic Parkinson's disease
Anna Kurz et al.
PARKINSONISM & RELATED DISORDERS (2021)
Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson's disease
Shulei He et al.
TRANSLATIONAL NEURODEGENERATION (2021)
Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease
Meng Cai et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Analysis of Serum miRNAs in Alzheimer's Disease
Liu Lu et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2021)
Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer's disease
Zhiqi Song et al.
ANIMAL MODELS AND EXPERIMENTAL MEDICINE (2021)
High-Throughput Sequencing of BACHD Mice Reveals Upregulation of Neuroprotective miRNAs at the Pre-Symptomatic Stage of Huntington's Disease
Isabella G. Olmo et al.
ASN NEURO (2021)
MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer's disease by RNA sequencing
Li Zeng et al.
NEURAL REGENERATION RESEARCH (2021)
DRD2 methylation to differentiate dementia with Lewy bodies from Parkinson's disease
Yuki Ozaki et al.
ACTA NEUROLOGICA SCANDINAVICA (2020)
MicroRNA-134-5p inhibition rescues long-term plasticity and synaptic tagging/capture in an Aβ(1-42)-induced model of Alzheimer's disease
Nimmi Baby et al.
AGING CELL (2020)
Acetylation changes tau interactome to degrade tau in Alzheimer's disease animal and organoid models
Heesun Choi et al.
AGING CELL (2020)
Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease
Nicholas S. Caron et al.
NUCLEIC ACIDS RESEARCH (2020)
Increased miR-34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS-JNK-p53 pathway in Alzheimer's Disease
Zhongli Shi et al.
AGING CELL (2020)
Up-regulation of microRNA-375 ameliorates the damage of dopaminergic neurons, reduces oxidative stress and inflammation in Parkinson's disease by inhibiting SP1
Li-Jun Cai et al.
AGING-US (2020)
Identifying lncRNA-miRNA-mRNA networks to investigate Alzheimer's disease pathogenesis and therapy strategy
Nana Ma et al.
AGING-US (2020)
Knockdown of long non-coding RNA SOX21-AS1 attenuates amyloid-β-induced neuronal damage by sponging miR-107
Wanru Xu et al.
BIOSCIENCE REPORTS (2020)
Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington's disease mice
Lucile Megret et al.
BMC BIOINFORMATICS (2020)
A Prion Epigenetic Switch Establishes an Active Chromatin State
Zachary H. Harvey et al.
CELL (2020)
Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models
Rachel Kuta et al.
CELL STRESS & CHAPERONES (2020)
MiR-29c protects against inflammation and apoptosis in Parkinson's disease model in vivo and in vitro by targeting SP1
Ruili Wang et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2020)
MicroRNAs and HDAC4 protein expression in the skeletal muscle of ALS patients
Valentina Pegoraro et al.
CLINICAL NEUROPATHOLOGY (2020)
MiR-340 Reduces the Accumulation of Amyloid-β Through Targeting BACE1 (β-site Amyloid Precursor Protein Cleaving Enzyme 1) in Alzheimer's Disease
Xianpei Tan et al.
CURRENT NEUROVASCULAR RESEARCH (2020)
MiR-335-5p Inhibits β-Amyloid (Aβ) Accumulation to Attenuate Cognitive Deficits Through Targeting c-jun-N-terminal Kinase 3 in Alzheimer's Disease
Dan Wang et al.
CURRENT NEUROVASCULAR RESEARCH (2020)
Dysregulation of histone acetylation pathways in hippocampus and frontal cortex of Alzheimer?s disease patients
Estelle Schueller et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2020)
Diagnostic value of miR-193a-3p in Alzheimer's disease and miR-193a-3p attenuates amyloid-β induced neurotoxicity by targeting PTEN
Fengjun Cao et al.
EXPERIMENTAL GERONTOLOGY (2020)
Modified level of miR-376a is associated with Parkinson's disease
Masoud Baghi et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease
Tong-Yao Hou et al.
JOURNAL OF NEUROCHEMISTRY (2020)
Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers
Jazmyne L. Jackson et al.
MOLECULAR NEURODEGENERATION (2020)
Invited Review: The role of prion-like mechanisms in neurodegenerative diseases
Z. Jaunmuktane et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2020)
DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations
Byung Woo Kim et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2020)
MicroRNA-150 serves as a diagnostic biomarker and is involved in the inflammatory pathogenesis of Parkinson's disease
Haiting Li et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2020)
Comprehensive analysis of PM20D1 QTL in Alzheimer's disease
Jose Vicente Sanchez-Mut et al.
CLINICAL EPIGENETICS (2020)
Evaluation of Biochemical and Epigenetic Measures of Peripheral Brain-Derived Neurotrophic Factor (BDNF) as a Biomarker in Huntington's Disease Patients
Ashley Gutierrez et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)
Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis
Noemi De Luna et al.
SCIENTIFIC REPORTS (2020)
Integrated analysis of miRNA and mRNA expression in the blood of patients with Alzheimer's disease
Zongwen Wang et al.
MOLECULAR MEDICINE REPORTS (2020)
MiRNA Profiling in Plasma Neural-Derived Small Extracellular Vesicles from Patients with Alzheimer's Disease
Maria Serpente et al.
CELLS (2020)
MicroRNA Alterations in a Tg501 Mouse Model of Prion Disease
Janne M. Toivonen et al.
BIOMOLECULES (2020)
Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt-Jakob disease
Luke C. Dabin et al.
ACTA NEUROPATHOLOGICA (2020)
Genome-wide profiling and predicted significance of post-mortem brain microRNA in Alzheimer's disease
Adriane D. Henriques et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2020)
DNA methylation study of Huntington's disease and motor progression in patients and in animal models
Ake T. Lu et al.
NATURE COMMUNICATIONS (2020)
Bioinformatic analysis of a microRNA regulatory network in Huntington's disease
Zhi-Min Wang et al.
JOURNAL OF INTEGRATIVE NEUROSCIENCE (2020)
Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis
Greig Joilin et al.
BRAIN COMMUNICATIONS (2020)
Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients
Sokhna M. S. Yakhine-Diop et al.
MOLECULAR NEUROBIOLOGY (2019)
HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease
L. Mahady et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2019)
MiR-105 and miR-9 regulate the mRNA stability of neuronal intermediate filaments. Implications for the pathogenesis of amyotrophic lateral sclerosis (ALS)
Zachary C. E. Hawley et al.
BRAIN RESEARCH (2019)
5-methylcytosine and 5-hydroxymethylcytosine in brains of patients with multiple system atrophy and patients with Parkinson's disease
Oliver Kaut et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2019)
Identification of potential blood biomarkers for Parkinson's disease by gene expression and DNA methylation data integration analysis
Changliang Wang et al.
CLINICAL EPIGENETICS (2019)
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease
Adam R. Smith et al.
CLINICAL EPIGENETICS (2019)
Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS
Andre Varcianna et al.
EBIOMEDICINE (2019)
Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis
Eva Pigna et al.
EBIOMEDICINE (2019)
The dark side of HDAC inhibition in ALS
Anne-Laurence Boutillier et al.
EBIOMEDICINE (2019)
Meta-analyses identify differentially expressed micrornas in Parkinson's disease
Jessica Schulz et al.
ANNALS OF NEUROLOGY (2019)
Identification of a circulating miRNA signature in extracellular vesicles collected from amyotrophic lateral sclerosis patients
Daniel Saucier et al.
BRAIN RESEARCH (2019)
Identification of miRNA-7 as a regulator of brain-derived neurotrophic factor/α-synuclein axis in atrazine-induced Parkinson's disease by peripheral blood and brain microRNA profiling
Bingyun Li et al.
CHEMOSPHERE (2019)
MicroRNA-135b alleviates MPP+-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis
Rong Zeng et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2019)
ERα Gene Promoter Methylation in Cognitive Function and Quality of Life of Patients With Alzheimer Disease
Kai-Xiu Li et al.
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2019)
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel et al.
MOLECULAR & CELLULAR PROTEOMICS (2019)
Regulation of histone arginine methylation/demethylation by methylase and demethylase
Jing Zhang et al.
MOLECULAR MEDICINE REPORTS (2019)
MicroRNA-195 triggers neuroinflammation in Parkinson's disease in a Rho-associated kinase 1-dependent manner
Yi Ren et al.
MOLECULAR MEDICINE REPORTS (2019)
Decreased Glycogenolysis by miR-338-3p Promotes Regional Glycogen Accumulation Within the Spinal Cord of Amyotrophic Lateral Sclerosis Mice
Chunyu Li et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Differential Methylation Levels in CpGs of the BIN1 Gene in Individuals With Alzheimer Disease
David Salcedo-Tacuma et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2019)
A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease
Mohsen Ghanbari et al.
HUMAN MUTATION (2019)
MicroRNA-326 suppresses iNOS expression and promotes autophagy of dopaminergic neurons through the JNK signaling by targeting XBP1 in a mouse model of Parkinson's disease
Xiao-Hui Zhao et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
MicroRNA-190 alleviates neuronal damage and inhibits neuroinflammation via Nlrp3 in MPTP-induced Parkinson's disease mouse model
Qiang Sun et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Class I and II histone deacetylase expression is not altered in human amyotrophic lateral sclerosis: Neuropathological and positron emission tomography molecular neuroimaging evidence
Amanda M. Dios et al.
MUSCLE & NERVE (2019)
miR-146a and miR-181a are involved in the progression of mild cognitive impairment to Alzheimer's disease
Abulaish Ansari et al.
NEUROBIOLOGY OF AGING (2019)
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms
Peipei Li et al.
NATURE COMMUNICATIONS (2019)
MicroRNA Expression Profiling Screen miR-3557/324-Targeted CaMK/mTOR in the Rat Striatum of Parkinson's Disease in Regular Aerobic Exercise
Wenfeng Liu et al.
BIOMED RESEARCH INTERNATIONAL (2019)
DNA methylation signature of human hippocampus in Alzheimer's disease is linked to neurogenesis
Miren Altuna et al.
CLINICAL EPIGENETICS (2019)
Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson's disease patients
Ruben Fernandez-Santiago et al.
CLINICAL EPIGENETICS (2019)
MicroRNA-200a-3p Mediates Neuroprotection in Alzheimer-Related Deficits and Attenuates Amyloid-Beta Overproduction and Tau Hyperphosphorylation via Coregulating BACE1 and PRKACB
Linlin Wang et al.
FRONTIERS IN PHARMACOLOGY (2019)
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
Elisabeth Rossaert et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
Altered mitochondrial DNA methylation and mitochondrial DNA copy number in an APP/PS1 transgenic mouse model of Alzheimer disease
YingYing Xu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease
Jianzhong Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Mir-17∼92 Confers Motor Neuron Subtype Differential Resistance to ALS-Associated Degeneration
Ying-Tsen Tung et al.
CELL STEM CELL (2019)
MiR-410 exerts neuroprotective effects in a cellular model of Parkinson's disease induced by 6-hydroxydopamine via inhibiting the PTEN/AKT/mTOR signaling pathway
Hanming Ge et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2019)
MicroRNA expression profiles of neuron-derived extracellular vesicles in plasma from patients with amyotrophic lateral sclerosis
Masataka Katsu et al.
NEUROSCIENCE LETTERS (2019)
miR-133b is a potential diagnostic biomarker for Alzheimer's disease and has a neuroprotective role
Qin Yang et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2019)
Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis
Christina L. Klatt et al.
CELLS (2019)
HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice
Taewoo Kim et al.
EXPERIMENTAL NEUROBIOLOGY (2019)
Perspectives on miRNAs as Epigenetic Markers in Osteoporosis and Bone Fracture Risk: A Step Forward in Personalized Diagnosis
Michela Bottani et al.
FRONTIERS IN GENETICS (2019)
Acetylation as a major determinant to microtubule-dependent autophagy: Relevance to Alzheimer's and Parkinson disease pathology
A. R. Esteves et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
Genome-wide identification of microRNAs regulating the human prion protein
Daniel Pease et al.
BRAIN PATHOLOGY (2019)
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains
Hans-Ulrich Klein et al.
NATURE NEUROSCIENCE (2019)
Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms
Maria Masnata et al.
ACTA NEUROPATHOLOGICA (2019)
Identification of circulating microRNA signatures as potential biomarkers in the serum of elk infected with chronic wasting disease
Jessy A. Slota et al.
SCIENTIFIC REPORTS (2019)
MiR-361-3p inhibits β-amyloid accumulation and attenuates cognitive deficits through targeting BACE1 in Alzheimer's disease
Yangfei Ji et al.
JOURNAL OF INTEGRATIVE NEUROSCIENCE (2019)
Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease
Juan Young et al.
NEUROLOGY-GENETICS (2019)
Systematic genetic interaction studies identify histone demethylase Utx as potential target for ameliorating Huntington's disease
Wan Song et al.
HUMAN MOLECULAR GENETICS (2018)
Dual MicroRNA to Cellular Prion Protein Inhibits Propagation of Pathogenic Prion Protein in Cultured Cells
Sang-Gyun Kang et al.
MOLECULAR NEUROBIOLOGY (2018)
Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson's Disease
Ana R. Esteves et al.
MOLECULAR NEUROBIOLOGY (2018)
MicroRNAs in CSF as prodromal biomarkers for Huntington disease in the PREDICT-HD study
Eric R. Reed et al.
NEUROLOGY (2018)
Aberrant DNA methylation associated with Alzheimer's disease in the superior temporal gyrus
Zhan Gao et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)
Increase in DNA methylation in patients with amyotrophic lateral sclerosis carriers of not fully penetrant SOD1 mutations
Fabio Coppede et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2018)
A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer's Disease
Xiong Wang et al.
BIOLOGICAL PSYCHIATRY (2018)
Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis
Mariah L. Hoye et al.
BRAIN (2018)
Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS
Anika M. Helferich et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease
Edith L. Pfister et al.
HUMAN GENE THERAPY (2018)
Exploring microRNA Biomarker for Amyotrophic Lateral Sclerosis
Y-h. Taguchi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
DNA methylation of TOMM40-APOE-APOC2 in Alzheimer's disease
Yvonne Shao et al.
JOURNAL OF HUMAN GENETICS (2018)
More than Just a Phase: Prions at the Crossroads of Epigenetic Inheritance and Evolutionary Change
Anupam K. Chakravarty et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS
Roy Maimon et al.
JOURNAL OF NEUROSCIENCE (2018)
Bioinformatic analysis of microRNA expression in Huntington's disease
Xiaoyu Dong et al.
MOLECULAR MEDICINE REPORTS (2018)
MicroRNA Expression Levels Are Altered in the Cerebrospinal Fluid of Patients with Young-Onset Alzheimer's Disease
Paul M. McKeever et al.
MOLECULAR NEUROBIOLOGY (2018)
Upregulation of histone deacetylase 2 in laser capture nigral microglia in Parkinson's disease
Yuyan Tan et al.
NEUROBIOLOGY OF AGING (2018)
MicroRNA alterations in iPSC-derived dopaminergic neurons from Parkinson disease patients
Eduard Tolosa et al.
NEUROBIOLOGY OF AGING (2018)
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis
Jose Manuel Matamala et al.
NEUROBIOLOGY OF AGING (2018)
MicroRNA-16 targets mRNA involved in neurite extension and branching in hippocampal neurons during presymptomatic prion disease
Kristyn Burak et al.
NEUROBIOLOGY OF DISEASE (2018)
Elevated Global DNA Methylation Is Not Exclusive to Amyotrophic Lateral Sclerosis and Is Also Observed in Spinocerebellar Ataxia Types 1 and 2
Hamid Hamzeiy et al.
NEURODEGENERATIVE DISEASES (2018)
Effects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS Mice
Daniela Buonvicino et al.
NEUROSCIENCE (2018)
Pyrosequencing analysis of methylation levels of clock genes in leukocytes from Parkinson's disease patients
Wei Mao et al.
NEUROSCIENCE LETTERS (2018)
Pathological histone acetylation in Parkinson's disease: Neuroprotection and inhibition of microglial activation through SIRT 2 inhibition
Ian F. Harrison et al.
NEUROSCIENCE LETTERS (2018)
MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice
Peter Langfelder et al.
PLOS ONE (2018)
The associations of two SNPs in miRNA-146a and one SNP in ZBTB38-RASA2 with the disease susceptibility and the clinical features of the Chinese patients of sCJD and FFI
Chen Gao et al.
PRION (2018)
miRNA-based signatures in cerebrospinal fluid as potential diagnostic tools for early stage Parkinson’s disease
Marcia Cristina T. dos Santos et al.
Oncotarget (2018)
Analysis of microRNA and Gene Expression Profiles in Alzheimer's Disease: A Meta-Analysis Approach
Shirin Moradifard et al.
SCIENTIFIC REPORTS (2018)
Supplemental Treatment for Huntington's Disease with miR-132 that Is Deficient in Huntington's Disease Brain
Masashi Fukuoka et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2018)
Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD
Boris Kantor et al.
MOLECULAR THERAPY (2018)
Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition
Florian A. Siebzehnrubl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Mitochondrial DNA copy number and D-loop region methylation in carriers of amyotrophic lateral sclerosis gene mutations
Andrea Stoccoro et al.
EPIGENOMICS (2018)
MicroRNA expression analysis identifies a subset of downregulated miRNAs in ALS motor neuron progenitors
Mafalda Rizzuti et al.
SCIENTIFIC REPORTS (2018)
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
Karolina Pircs et al.
CELL REPORTS (2018)
Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis
Maria Liguori et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
DNA Methylation Profiles in Whole Blood of Huntington's Disease Patients
Maja Zadel et al.
FRONTIERS IN NEUROLOGY (2018)
Wide-Ranging Analysis of MicroRNA Profiles in Sporadic Amyotrophic Lateral Sclerosis Using Next-Generation Sequencing
Bruna De Felice et al.
FRONTIERS IN GENETICS (2018)
DNA Hypomethylation in Blood Links B3GALT4 and ZADH2 to Alzheimer's Disease
Andy Madrid et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex
Sarah J. Marzi et al.
NATURE NEUROSCIENCE (2018)
Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model
Karolina J. Janczura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis
Wenting Guo et al.
CELL STRESS (2018)
Nuclear Accumulation of Histone Deacetylase 4 (HDAC4) Exerts Neurotoxicity in Models of Parkinson's Disease
Qimei Wu et al.
MOLECULAR NEUROBIOLOGY (2017)
CSF microRNA Profiling in Alzheimer's Disease: a Screening and Validation Study
Adria Dangla-Valls et al.
MOLECULAR NEUROBIOLOGY (2017)
MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian
Mingshu Mo et al.
ONCOTARGET (2017)
Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies
Lin Guo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Increased circulating microRNAs miR-342-3p and miR-21-5p in natural sheep prion disease
David Sanz Rubio et al.
JOURNAL OF GENERAL VIROLOGY (2017)
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease
Elizabeth M. Ellison et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease
Luana Naia et al.
JOURNAL OF NEUROSCIENCE (2017)
Increased expression of prion protein gene is accompanied by demethylation of CpG sites in a mouse embryonal carcinoma cell line, P19C6
Wuyun Dalai et al.
JOURNAL OF VETERINARY MEDICAL SCIENCE (2017)
CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene
Wuyun Dalai et al.
JOURNAL OF VETERINARY MEDICAL SCIENCE (2017)
The emerging field of epigenetics in neurodegeneration and neuroprotection
Jee-Yeon Hwang et al.
NATURE REVIEWS NEUROSCIENCE (2017)
Epigenetic approach to early-onset Parkinson's disease: low methylation status of SNCA and PARK2 promoter regions
Isil Ezgi Eryilmaz et al.
NEUROLOGICAL RESEARCH (2017)
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice
Andrea Lapucci et al.
NEUROSCIENCE LETTERS (2017)
Inhibition of HDAC6 increases acetylation of peroxiredoxin1/2 and ameliorates 6-OHDA induced dopaminergic injury
Wencheng Jian et al.
NEUROSCIENCE LETTERS (2017)
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
Wenting Guo et al.
NATURE COMMUNICATIONS (2017)
A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice
Nuria Suelves et al.
SCIENTIFIC REPORTS (2017)
miR-196a Enhances Neuronal Morphology through Suppressing RANBP10 to Provide Neuroprotection in Huntington's Disease
Lu-Shiun Her et al.
THERANOSTICS (2017)
Parkinson's disease is associated with DNA methylation levels in human blood and saliva
Yu-Hsuan Chuang et al.
GENOME MEDICINE (2017)
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
E. Taskesen et al.
SCIENTIFIC REPORTS (2017)
Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease
Junghee Lee et al.
ACTA NEUROPATHOLOGICA (2017)
Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease
Mark T. W. Ebbert et al.
ACTA NEUROPATHOLOGICA (2017)
miRNAs in synapse development and synaptic plasticity
Zhonghua Hu et al.
CURRENT OPINION IN NEUROBIOLOGY (2017)
DNA methylation age-acceleration is associated with disease duration and age at onset in C9orf72 patients
Ming Zhang et al.
ACTA NEUROPATHOLOGICA (2017)
MicroRNA-27a reduces mutant hutingtin aggregation in an in vitro model of Huntington's disease
Jae-Jun Ban et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease
Jinying Zhao et al.
ALZHEIMERS & DEMENTIA (2017)
RNA-binding proteins with prion-like domains in health and disease
Alice Ford Harrison et al.
BIOCHEMICAL JOURNAL (2017)
Regulation of Histone Acetylation by Autophagy in Parkinson Disease
Goonho Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Peripheral Blood MicroRNA Expression Profiles in Alzheimer's Disease: Screening, Validation, Association with Clinical Phenotype and Implications for Molecular Mechanism
Ru-Jing Ren et al.
MOLECULAR NEUROBIOLOGY (2016)
Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
Steve Horvath et al.
AGING-US (2016)
Micro-RNAs in cognition and cognitive disorders: Potential for novel biomarkers and therapeutics
Bisrat T. Woldemichael et al.
BIOCHEMICAL PHARMACOLOGY (2016)
Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease
Zachary M. March et al.
BRAIN RESEARCH (2016)
DNA methylation profiling in human Huntington's disease brain
Rebecca A. G. De Souza et al.
HUMAN MOLECULAR GENETICS (2016)
MicroRNA abundance is altered in synaptoneurosomes during prion disease
Amrit S. Boese et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2016)
MiR-144-3p and Its Target Gene β-Amyloid Precursor Protein Regulate 1-Methyl-4-Phenyl-1,2-3,6-Tetrahydropyridine-Induced Mitochondrial Dysfunction
Kuo Li et al.
MOLECULES AND CELLS (2016)
HDAC6 alleviates prion peptide-mediated neuronal death via modulating PI3K-Akt-mTOR pathway
Ting Zhu et al.
NEUROBIOLOGY OF AGING (2016)
Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT
Cesar L. Moreno et al.
NEUROBIOLOGY OF DISEASE (2016)
Identification of miRNAs as Potential Biomarkers in Cerebrospinal Fluid from Amyotrophic Lateral Sclerosis Patients
Michele Benigni et al.
NEUROMOLECULAR MEDICINE (2016)
Parkinson's disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus
Roman Tatura et al.
PARKINSONISM & RELATED DISORDERS (2016)
Circulating microRNAs in Huntington's disease: Emerging mediators in metabolic impairment
C. Diez-Planelles et al.
PHARMACOLOGICAL RESEARCH (2016)
Histone Modifications and Cancer
James E. Audia et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Common DNA methylation alterations of Alzheimer's disease and aging in peripheral whole blood
Hongdong Li et al.
ONCOTARGET (2016)
microRNA Profiles in Parkinson's Disease Prefrontal Cortex
Andrew G. Hoss et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Genome-wide12 DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease
Corey T. Watson et al.
GENOME MEDICINE (2016)
MiRNA expression profiles in the brains of mice infected with scrapie agents 139A, ME7 and S15
Chen Gao et al.
EMERGING MICROBES & INFECTIONS (2016)
Aberration of miRNAs Expression in Leukocytes from Sporadic Amyotrophic Lateral Sclerosis
YongPing Chen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)
Marked Differences in C9orf72 Methylation Status and Isoform Expression between C9/ALS Human Embryonic and Induced Pluripotent Stem Cells
Yaara Cohen-Hadad et al.
STEM CELL REPORTS (2016)
The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice
Haiqun Jia et al.
PLOS ONE (2016)
miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington's Disease Monkey Neural Cells
Tanut Kunkanjanawan et al.
PLOS ONE (2016)
Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer's Disease and Amnestic Mild Cognitive Impairment
Nobuyuki Kobayashi et al.
PLoS One (2016)
LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington's Disease
Vanita Chopra et al.
JOURNAL OF HUNTINGTONS DISEASE (2016)
InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams
Henry Heberle et al.
BMC BIOINFORMATICS (2015)
Serum MicroRNA Profiles Serve as Novel Biomarkers for the Diagnosis of Alzheimer's Disease
Hui Dong et al.
DISEASE MARKERS (2015)
Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients
Ruben Fernandez-Santiago et al.
EMBO MOLECULAR MEDICINE (2015)
DNA Methylation in Memory Formation: Emerging Insights
Frankie D. Heyward et al.
NEUROSCIENTIST (2015)
The epigenetics of aging and neurodegeneration
Roy Lardenoije et al.
PROGRESS IN NEUROBIOLOGY (2015)
Identification of plasma microRNAs as a biomarker of sporadic Amyotrophic Lateral Sclerosis
Ikuko Takahashi et al.
MOLECULAR BRAIN (2015)
Genetic deletion of the Histone Deacetylase 6 exacerbates selected behavioral deficits in the R6/1 mouse model for Huntington's disease
Alienor Ragot et al.
BRAIN AND BEHAVIOR (2015)
Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains
Guang Bai et al.
HUMAN MOLECULAR GENETICS (2015)
Scrapie Infection in Experimental Rodents and SMB-S15 Cells Decreased the Brain Endogenous Levels and Activities of Sirt1
Jing Wang et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2015)
The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease
Xianjun Dong et al.
PLOS ONE (2015)
HDAC inhibition imparts beneficial transgenerational effects in Huntington's disease mice via altered DNA and histone methylation
Haiqun Jia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Serum microRNAs in patients with genetic amyotrophic lateral sclerosis and pre-manifest mutation carriers
Axel Freischmidt et al.
BRAIN (2014)
Prion disease and the 'protein-only hypothesis'
Jiyan Ma et al.
AMYLOIDS IN HEALTH AND DISEASE (2014)
MiRNA Profile in the Substantia Nigra of Parkinson's Disease and Healthy Subjects
Lucia F. Cardo et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2014)
5-Hydroxymethylcytosine is a predominantly stable DNA modification
Martin Bachman et al.
NATURE CHEMISTRY (2014)
MicroRNA-206: A Potential Circulating Biomarker Candidate for Amyotrophic Lateral Sclerosis
Janne M. Toivonen et al.
PLOS ONE (2014)
MicroRNAs and synaptic plasticity-a mutual relationship
Ayla Aksoy-Aksel et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis
Andrew G. Hoss et al.
PLOS GENETICS (2014)
Analysis of microRNA from archived formalin-fixed paraffin-embedded specimens of amyotrophic lateral sclerosis
Koichi Wakabayashi et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease
Fengli Wang et al.
HUMAN MOLECULAR GENETICS (2013)
Profile of microRNAs in the plasma of Parkinson's disease patients and healthy controls
Lucia F. Cardo et al.
JOURNAL OF NEUROLOGY (2013)
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
Jae-Kyo Jeong et al.
NEUROBIOLOGY OF AGING (2013)
DNA Methylation and Its Basic Function
Lisa D. Moore et al.
NEUROPSYCHOPHARMACOLOGY (2013)
Anti-prion activity of an RNA aptamer and its structural basis
Tsukasa Mashima et al.
NUCLEIC ACIDS RESEARCH (2013)
MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington's Disease-Related Mechanisms
Ana Jovicic et al.
PLOS ONE (2013)
Detection and mapping of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA
Andrew H. Laszlo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Altered microRNA expression profile in amyotrophic lateral sclerosis: a role in the regulation of NFL mRNA levels
Danae Campos-Melo et al.
MOLECULAR BRAIN (2013)
DNA methylation age of human tissues and cell types
Steve Horvath
GENOME BIOLOGY (2013)
Nonspecific Prion Protein-Nucleic Acid Interactions Lead to Different Aggregates and Cytotoxic Species
Bruno Macedo et al.
BIOCHEMISTRY (2012)
A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis
Bruna De Felice et al.
GENE (2012)
SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death
Jae-Suk Seo et al.
NEUROBIOLOGY OF AGING (2012)
TAR DNA-binding protein 43 in neurodegenerative disease
Alice S. Chen-Plotkin et al.
NATURE REVIEWS NEUROLOGY (2010)
Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation
Juan Nunez-Iglesias et al.
PLOS ONE (2010)
MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice
Andrew H. Williams et al.
SCIENCE (2009)
Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells
Mariana P. B. Gomes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
MicroRNA-373 induces expression of genes with complementary promoter sequences
Robert F. Place et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Covalent modification of DNA regulates memory formation
Courtney A. Miller et al.
NEURON (2007)
The hypothesis of the catalytic action of nucleic acid on the conversion of prion protein
Y Cordeiro et al.
PROTEIN AND PEPTIDE LETTERS (2005)
RNA molecules stimulate prion protein conversion
NR Deleault et al.
NATURE (2003)
分享论文
