期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 23, 期 18, 页码 -出版社
MDPI
DOI: 10.3390/ijms231810429
关键词
avian astrovirus; pathogenesis; visceral gout
资金
- Special fund for scientific innovation strategy-construction of high level Academy of Agriculture Science [202110TD, R2020PY-JX014, R2020QD-049, R2020PYJC001]
- Guangdong Laboratory for Lingnan Modern Agriculture Project [NZ2021015]
- Collaborative Innovation Center of GDAAS [XTXM202202]
- Science and Technology Planning Project of Jiangmen [2020030103310009038]
- Key Research and Development Program of Guangdong Province [2020B0202090004]
- Yunnan Liao Ming Expert Workstation [202105AF150077]
- Science and Technology Program of Guangdong Province [2021B1212030015]
- Zengcheng District Entrepreneurial Leading Team Project (2021)
This article reviews the recent discoveries in genetic diversity and variation of avian astroviruses, as well as the pathogenesis and relation to visceral gout in poultry. The aim is to gain insights into the prevention and control of visceral gout diseases in poultry and understand the possible producing process.
Avian astroviruses, including chicken astrovirus (CAstV), avian nephritisvirus (ANV), and goose astrovirus (GoAstV), are ubiquitous enteric RNA viruses associated with enteric disorders in avian species. Recent research has found that infection of these astroviruses usually cause visceral gout in chicken, duckling and gosling. However, the underlying mechanism remains unknown. In the current article, we review recent discoveries of genetic diversity and variation of these astroviruses, as well as pathogenesis after astrovirus infection. In addition, we discuss the relation between avian astrovirus infection and visceral gout in poultry. Our aim is to review recent discoveries about the prevention and control of the consequential visceral gout diseases in poultry, along with the attempt to reveal the possible producing process of visceral gout diseases in poultry.
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