4.5 Article

Chemical characterisation and in vitro wound healing activity of Tunisian ghee products

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WILEY
DOI: 10.1111/ijfs.16054

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Antioxidants; chemical characterisation; fibroblast migration; ghee; vitamins; wound healing

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Ayurvedic literature has proven the healing properties of ghee, which can be used for wound healing. This study compares different types of Tunisian ghee and finds that ghee with high antioxidant capacity and rich in vitamins A and E can improve fibroblast migration.
Ayurvedic literature has demonstrated the healing properties of ghee when used systemically and topically. Ghee possesses regenerative properties that can heal wounds, and therefore, the study aimed to compare different types of Tunisian ghee (traditional and industrial cow, goat and sheep) for their wound healing activity. Comparison of the ghee was achieved by studying their antioxidant activity, oxidative stability, fatty acids and vitamin composition analysis, as well as their ability to stimulate dermal fibroblast migration and wound healing process. This study indicates that this Tunisian product with high antioxidant capacity rich in vitamins A and E could improve fibroblast migration, suggesting thus an application as a healing element in an ointment base.

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