期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 220, 期 -, 页码 537-572出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2022.08.098
关键词
Carbohydrate; Polysaccharides; Natural bioactives; Encapsulation; Nanocarriers; Drug delivery
This article summarizes the current developments in nano/micro-encapsulation techniques, with a focus on the encapsulation of natural bioactives using chitosan as a carrier. Polysaccharide-based nano/micro-formulations have emerged as a new trend in scientific research and development, with potential applications in drug delivery systems and nanocarrier formulations.
Nowadays, nano/micro-encapsulation as a pioneering technique may significantly improve the bioavailability and durability of Natural bioactives. For this purpose, chitosan as a bioactive cationic natural polysaccharide has been frequently used as a carrier because of its distinct chemical and biological properties, including polycationic nature, biocompatibility, and biodegradability. Moreover, polysaccharide-based nano/micro-formulations are a new and extensive trend in scientific research and development in the disciplines of biomedicine, bioorganic/ medicinal chemistry, pharmaceutics, agrochemistry, and the food industry. It promises a new paradigm in drug delivery systems and nanocarrier formulations. This review aims to summarize current developments in ap-proaches for designing innovative chitosan micro/nano-matrix, with an emphasis on the encapsulation of natural bioactives. The special emphasis led to a detailed integrative scientific achievement of the functionalities and abilities for encapsulating natural bioactives and mechanisms regulated in vitro/in vivo release in various bio-logical/physiological environments.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据