☆ 4.7 Article

Structure, selenization modification, and antitumor activity of a glucomannan from Platycodon grandiflorum

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Chemistry, Applied

Isolation, structural characterization and bioactivities of polysaccharides from Laminaria japonica: A review

Hai-Yang Li et al.

Summary: This review provides a comprehensive summary of the extraction, purification, structural characterization, and biological activities of Laminaria japonica polysaccharides, offering valuable insights for further research, production, and application in functional foods and therapeutic agents.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Plant Sciences

Ganoderma lucidum polysaccharides inhibit in vitro tumorigenesis, cancer stem cell properties and epithelial-mesenchymal transition in oral squamous cell carcinoma

Marcela Rodrigues de Camargo et al.

Summary: The polysaccharides of Ganoderma lucidum have the potential to be an important ally for tongue squamous cell carcinoma treatment, as they can alter the behavior and morphology of tumor cells, as well as downregulate cancer stem cells and EMT markers.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

添加到收藏夹

Article Chemistry, Applied

Structure, anti-tumor activity, and potential anti-tumor mechanism of a fungus polysaccharide from Fomes officinalis

Shaojie Zhang et al.

Summary: A homogeneous polysaccharide FOP80-1 with anti-tumor activity was purified from Fomes officinalis, showing potential mechanisms of inhibiting tumor proliferation, invasion, and metastasis by increasing ROS, arresting cell cycle, inducing apoptosis, and suppressing angiogenesis.

CARBOHYDRATE POLYMERS (2022)

添加到收藏夹

Article Chemistry, Applied

Conjugation of soy protein isolate (SPI) with pectin: effects of structural modification of the grafting polysaccharide

Xiaobin Ma et al.

Summary: There has been a recent interest in enhancing the emulsifying properties of soy protein isolate (SPI) through Maillard reaction. Pectin, as a commonly-used grafting polysaccharide, has shown usefulness in modifying proteins. The structural characteristics of pectin, such as molecular weight and degree of methoxylation and acetylation, significantly influence conjugation. Lower molecular weight and fewer main chains in pectin result in a higher conjugate yield when conjugated with SPI. The protein structure becomes more loosened after the Maillard reaction, as indicated by reduced fluorescence intensity and surface hydrophobicity. Enzymolysis pectin proves to be the optimal grafting polysaccharide, considering its simple preparation procedures and highest emulsifying properties of the resulting conjugates.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Applied

Extraction, derivatization and antioxidant activities of onion polysaccharide

Shiyang Zhou et al.

Summary: In this study, purified polysaccharides were extracted from fresh onions using hot water extraction, protein removal, and dialysis treatment. The structure of onion polysaccharides was confirmed using various NMR techniques. Antioxidant activities of onion polysaccharide and its derivatives were tested in vitro, showing good antioxidant activity, with phosphorylated polysaccharide demonstrating similar activity to the positive control Vc.

FOOD CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Applied

A dandelion polysaccharide and its selenium nanoparticles: Structure features and evaluation of anti-tumor activity in zebrafish models

Shaojie Zhang et al.

Summary: In this study, a monodisperse spherical nanoparticle Tw-TMP-SeNP was fabricated to enhance the anti-tumor activity of inulin fructan TMP50-2 obtained from dandelion. Both in vitro and in vivo experiments confirmed the significant inhibitory effect of Tw-TMP-SeNP on the proliferation, migration, and angiogenesis of cancer cells, highlighting its potential as a treatment for various cancers.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Article Chemistry, Applied

Structure features, selenylation modification, and improved anti-tumor activity of a polysaccharide from Eriobotrya japonica

Shaojie Zhang et al.

Summary: A homogeneous polysaccharide EJP90-1 was extracted from the leaves of E. japonica, and further modified with sodium selenite-nitric acid to enhance its anti-tumor activity. The selenylation modification derivative EJP90-1-Se exhibited significant antiproliferative activity against cancer cells, and was confirmed to inhibit cell proliferation, migration, and angiogenesis through zebrafish models.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Review Chemistry, Applied

Recent advances in polysaccharides from Lentinus edodes (Berk.): Isolation, structures and bioactivities

Kangjia Sheng et al.

Summary: Lentinus edodes, commonly known as shiitake mushroom, is a widely cultivated edible mushroom in East Asia with rich bioactive polysaccharides, especially beta-glucans. Research on the polysaccharides from L. edodes has shown various remarkable biological activities such as antioxidant, anti-tumor, and immunomodulatory effects, drawing attention from scholars worldwide. Recent studies on the isolation methods, structural features, bioactivities, and mechanisms of L. edodes polysaccharides provide valuable research insights for their further application as therapeutic agents and functional foods.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Applied

Structural elucidation and immunomodulatory evaluation of a polysaccharide from Stevia rebaudiana leaves

Zhengguo Li et al.

Summary: This study extracted a polysaccharide SRP70-1 from Stevia rebaudiana, analyzed its structure and immunological functions, and found that it may be helpful for the development of functional foods.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Construction and antitumor activity of selenium nanoparticles decorated with the polysaccharide extracted from Citrus limon (L.) Burm. f. (Rutaceae)

Linan Zhou et al.

Summary: The study synthesized stable and well-dispersed selenium nanoparticles, CL90-Tw-SeNP2, which demonstrated significant anti-tumor effects against HepG2 cells. By inducing cell apoptosis, CL90-Tw-SeNP2 showed potential for inhibiting the proliferation of liver cancer cells.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Chemistry, Applied

Structural properties and in vitro and in vivo immunomodulatory activity of an arabinofuranan from the fruits of Akebia quinata

Huimei Wang et al.

Summary: In this study, a natural active polysaccharide AQP70-3 was isolated from Akebia quinata fruits for the first time, showing immunomodulatory activity by stimulating phagocytic activity and increasing cytokine levels of immune cells. Furthermore, AQP70-3 was found to enhance reactive oxygen species and nitric oxide production in zebrafish embryo model.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural elucidation of an immunological arabinan from the rhizomes of Ligusticum chuanxiong, a traditional Chinese medicine

Shaojie Zhang et al.

Summary: In this study, an immunological arabinan, LCP70-2A, was isolated from Ligusticum chuanxiong for the first time. Physicochemical characterization revealed its homogeneous polysaccharide nature and potential as an immunological enhancement supplement by activating macrophages and promoting the secretion of immunoregulatory factors.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Food Science & Technology

Extraction/synthesis and biological activities of selenopolysaccharide

Wenjian Yang et al.

Summary: Selenium is an essential trace element that plays an important role in enhancing immunity and anti-tumor activities. Organic selenium polysaccharides with high selenium content have become a major research focus. The future development and utilization of selenium polysaccharides in healthcare or medicine is of great significance.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Applied

Bioguided chemical characterization of pequi (Caryocar brasiliense) fruit peels towards an anti-diabetic activity

Alisson S. P. Caldeira et al.

Summary: Pequi fruit peels contain polyphenols that exhibit anti-diabetic potential by inhibiting cytokines involved in insulin resistance and α-glucosidase activity, reducing blood glucose levels in mice. The presence of phenolic acids and tannins in the peels highlights their potential for developing functional foods to manage type-2 diabetes.

FOOD CHEMISTRY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Characterization of an antioxidant pectic polysaccharide from Platycodon grandiflorus

Yuan-Feng Zou et al.

Summary: The study extracted a pectic polysaccharide, PGP-I-I, from Platycodon grandiflorus roots, which was found to promote cellular antioxidant defense and protect against oxidative damage.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Review Chemistry, Applied

Triple-helix polysaccharides: Formation mechanisms and analytical methods

Xiaoyu Guo et al.

Summary: This review specifically examines the formation mechanisms, structure-activity relationships, and analytical methods for triple-helix polysaccharides. The insights provided can be valuable for exploring the biological activities of polysaccharides and their applications in the food and pharmaceutical industries.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Article Chemistry, Applied

Structural analysis and biological effects of a neutral polysaccharide from the fruits of Rosa laevigata

Jiaojiao Zhang et al.

Summary: A neutral water-soluble polysaccharide (RLP50-2) was extracted and purified from Rosa laevigata fruits, with monosaccharide composition mainly consisting of glucose, arabinose, and galactose. Structural analysis revealed specific glycosidic linkages and terminal constituents. Biological assays demonstrated immunomodulatory and antitumor activities of RLP50-2, suggesting its potential as a drug candidate in biomedicine.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural characteristics and in vitro and in vivo immunoregulatory properties of a gluco-arabinan from Angelica dahurica

Honglin Wang et al.

Summary: ADP80-2, a water-soluble polysaccharide obtained from Angelica dahurica, exhibits immunomodulatory effects by enhancing phagocytosis and nitric oxide production in macrophages. Its discovery holds promise for the development of novel immunomodulatory agents.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Article Chemistry, Applied

A fructan from Anemarrhena asphodeloides Bunge showing neuroprotective and immunoregulatory effects

Shaojie Zhang et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Chemistry, Applied

Studies on O-acetyl-glucomannans from Amorphophallus species: Comparison of fine structure

Xiao-Dan Shi et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Article Chemistry, Applied

Structural characterization, antioxidant and immunomodulatory activities of a neutral polysaccharide from Cordyceps militaris cultivated on hull-less barley

Ying Zhang et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Chemistry, Applied

A heteropolysaccharide purified from leaves of Ilex latifolia displaying immunomodulatory activity in vitro and in vivo

Zhaoyu Shi et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Chemistry, Applied

Characterization of selenium-containing polysaccharides isolated from selenium-enriched tea and its bioactivities

Yangeng Gu et al.

FOOD CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Applied

A novel polysaccharide from Castanea mollissima Blume: Preparation, characteristics and antitumor activities in vitro and in vivo

Xiao-dan Dong et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Modification and application of polysaccharide from traditional Chinese medicine such as Dendrobium officinale

Shiyu Huang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Article Chemistry, Applied

Isolation, structural elucidation, and immunoregulation properties of an arabinofuranan from the rinds of Garcinia mangostana

Shaojie Zhang et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Chemistry, Applied

Synthesis of Se-polysaccharide mediated by selenium oxychloride: Structure features and antiproliferative activity

Shengyong Zhu et al.

CARBOHYDRATE POLYMERS (2020)

添加到收藏夹

Article Chemistry, Applied

Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics

Le-Le Zhang et al.

FOOD CHEMISTRY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural characterization and hypoglycemic activity of an intracellular polysaccharide from Sanghuangporus sanghuang mycelia

Junwen Cheng et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Research progress on the biological activities of selenium polysaccharides

Ning Zhou et al.

FOOD & FUNCTION (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Protective effects of Platycodon grandiflorus polysaccharides against apoptosis induced by carbonyl cyanide 3-chlorophenylhydrazone in 3D4/21 cells

Cheng Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Natural polysaccharides exhibit anti-tumor activity by targeting gut microbiota

Liqiao Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Article Food Science & Technology

Functional polysaccharide Lentinan suppresses human breast cancer growth via inducing autophagy and caspase-7-mediated apoptosis

Weiyong Li et al.

JOURNAL OF FUNCTIONAL FOODS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Structural and conformational characterization of linear O-acetyl-glucomannan purified from gel of Aloe barbadensis Miller

Xiao-Dan Shi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Extraction, selenylation modification and antitumor activity of the glucan from Castanea mollissima Blume

Hongyan Li et al.

GLYCOCONJUGATE JOURNAL (2017)

添加到收藏夹

Article Chemistry, Applied

An O-acetyl-glucomannan from the rhizomes of Curculigo orchioides: Structural characterization and anti-osteoporosis activity in vitro

Xueqian Wang et al.

CARBOHYDRATE POLYMERS (2017)

添加到收藏夹

Article Chemistry, Medicinal

Effect of processing method on platycodin D content in Platycodon grandiflorum roots

Jaeyoung Kwon et al.

ARCHIVES OF PHARMACAL RESEARCH (2017)

添加到收藏夹

Article Chemistry, Applied

Synthesis of selenium-containing Artemisia sphaerocephala polysaccharides: Solution conformation and anti-tumor activities in vitro

Junlong Wang et al.

CARBOHYDRATE POLYMERS (2016)

添加到收藏夹

Article Chemistry, Applied

Sugar and acid content of Citrus prediction modeling using FT-IR fingerprinting in combination with multivariate statistical analysis

Seung Yeob Song et al.

FOOD CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Applied

Sulphation pattern analysis of chemically sulphated polysaccharide LbGp1 from Lycium barbarum by GC-MS

Yujiao Sun et al.

FOOD CHEMISTRY (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

Marie Vetizou et al.

SCIENCE (2015)

添加到收藏夹

Article Chemistry, Applied

Characterization and rheological study of the galactomannan extracted from seeds of Cassia grandis

Priscilla B. S. Albuquerque et al.

CARBOHYDRATE POLYMERS (2014)

添加到收藏夹

Article Chemistry, Applied

Chemical modification of an acidic polysaccharide (TAPA1) from Tremella aurantialba and potential biological activities

XiuJu Du et al.

FOOD CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Applied

Analysis of the monosaccharide composition of water-soluble polysaccharides from Sargassum fusiforme by high performance liquid chromatography/electrospray ionisation mass spectrometry

Xiaodan Wu et al.

FOOD CHEMISTRY (2014)

添加到收藏夹

Article Plant Sciences

In vivo and in vitro anti-tumor and anti-metastasis effects of Coriolus versicolor aqueous extract on mouse mammary 4T1 carcinoma

Ke-Wang Luo et al.

PHYTOMEDICINE (2014)

添加到收藏夹

Article Chemistry, Applied

Saponins from Platycodon grandiflorum inhibit hepatic lipogenesis through induction of SIRT1 and activation of AMP-activated protein kinase in high-glucose-induced HepG2 cells

Yong Pil Hwang et al.

FOOD CHEMISTRY (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

A homogalacturonan from the radix of Platycodon grandiflorum and the anti-angiogenesis activity of poly-/oligogalacturonic acids derived therefrom

Yuxia Xu et al.

CARBOHYDRATE RESEARCH (2011)

添加到收藏夹

Article Chemistry, Applied

Antioxidant activities from the aerial parts of Platycodon grandiflorum

Chang-Ho Jeong et al.

FOOD CHEMISTRY (2010)

添加到收藏夹

Article Immunology

Activation of mitogen-activated protein kinases and AP-1 by polysaccharide isolated from the radix of Platycodon grandiflorum in RAW 264.7 cells

YD Yoon et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.