4.7 Article

Complement factor H variants are associated with microangiopathy lesions in IgA nephropathy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Urology & Nephrology

The Role of Complement in Microangiopathic Lesions of IgA Nephropathy

Jingyi Li et al.

Summary: The study found that arteriolar microangiopathic (MA) lesions in IgA nephropathy (IgAN) patients are associated with complement deposition, increased levels of Gd-IgA1 and C3a, and rare genetic variations in complement-related genes.

KIDNEY INTERNATIONAL REPORTS (2022)

Article Transplantation

Glomerular endothelial activation, C4d deposits and microangiopathy in immunoglobulin A nephropathy

Hernan Trimarchi et al.

Summary: IgA nephropathy is a mesangial disease that involves not only the mesangium but also other glomerular components. Vascular damage triggered immune reactions and coagulation cascades, leading to kidney function decline. Research on MA/TMA lesions in IgAN patients varies in percentages and is strongly associated with hypertension.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

Article Urology & Nephrology

Interaction between GALNT12 and C1GALT1 Associates with Galactose-Deficient IgAl and IgA Nephropathy

Yan-Na Wang et al.

Summary: The study identified two novel loci, C1GALT1 and GALNT12, associated with serum levels of galactose-deficient IgA1 in patients with IgA nephropathy. The genetic interaction between GALNT12 and C1GALT1 was found to be significant, suggesting a key role of genetically conferred dysregulation of galactose-deficient IgA1 in the development of IgA nephropathy. Additionally, GALNT12 mRNA expression was significantly lower in patients with IgA nephropathy compared to healthy controls.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

Article Multidisciplinary Sciences

Evidences of histologic thrombotic microangiopathy and the impact in renal outcomes of patients with IgA nephropathy

Precil Diego Miranda de Menezes Neves et al.

PLOS ONE (2020)

Article Urology & Nephrology

Microangiopathic Lesions in IgA Nephropathy: A Cohort Study

Qingqing Cai et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2019)

Article Medicine, General & Internal

Coding and Noncoding Variants in CFH Act Synergistically for Complement Activation in Immunoglobulin A Nephropathy

Wei-yi Guo et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2018)

Article Urology & Nephrology

Fine Mapping Implicates a Deletion of CFHR1 and CFHR3 in Protection from IgA Nephropathy in Han Chinese

Jingyuan Xie et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)

Review Medicine, General & Internal

Primary glomerulonephritides

Juergen Floege et al.

LANCET (2016)

Review Urology & Nephrology

Current Understanding of the Role of Complement in IgA Nephropathy

Nicolas Maillard et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)

Article Urology & Nephrology

Complement Factor C4d Is a Common Denominator in Thrombotic Microangiopathy

Jamie S. Chua et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)

Review Urology & Nephrology

C3 glomerulopathy: consensus report

Matthew C. Pickering et al.

KIDNEY INTERNATIONAL (2013)

Article Genetics & Heredity

Genome-wide association study identifies susceptibility loci for IgA nephropathy

Ali G. Gharavi et al.

NATURE GENETICS (2011)

Article Multidisciplinary Sciences

Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk

Meike Heurich et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Urology & Nephrology

HLA Has Strongest Association with IgA Nephropathy in Genome-Wide Analysis

John Feehally et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)

Article Urology & Nephrology

The complement factor h R1210C mutation is associated with atypical hemolytic uremic syndrome

Ruben Martinez-Barricarte et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

Article Medicine, General & Internal

Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking

Anne E. Hughes et al.

PLOS MEDICINE (2007)

Article Multidisciplinary Sciences

Complement factor H polymorphism in age-related macular degeneration

RJ Klein et al.

SCIENCE (2005)

Review Biochemistry & Molecular Biology

The human complement factor H:: functional roles, genetic variations and disease associations

SR de Córdoba et al.

MOLECULAR IMMUNOLOGY (2004)

Article Biochemistry & Molecular Biology

Factor H binding to bone sialoprotein and osteopontin enables tumor cell evasion of complement-mediated attack

NS Fedarko et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)