Pulmonary air leak in COVID-19: time to learn from our mistakes

Article Critical Care Medicine

Lung Response to a Higher Positive End-Expiratory Pressure in Mechanically Ventilated Patients With COVID-19

Alessandro Protti et al.

Summary: Patients with early ARDS due to COVID-19 have a large potential for lung recruitment, but their compliance and Pa-CO2 may not improve with higher PEEP, possibly due to hyperinflation.

CHEST (2022)

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Letter Critical Care Medicine

Comparison of radiographic pneumothorax and pneumomediastinum in COVID-19 vs. non-COVID-19 acute respiratory distress syndrome

Daniel B. Knox et al.

INTENSIVE CARE MEDICINE (2022)

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Article Critical Care Medicine

Lung response to prone positioning in mechanically-ventilated patients with COVID-19

Alessandro Protti et al.

Summary: Prone positioning in COVID-19 patients decreases alveolar collapse, hyperinflation, and improves lung aeration. This supports the use of prone positioning in COVID-19, similar to its benefits in other cases of ARDS.

CRITICAL CARE (2022)

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Article Critical Care Medicine

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study

Brenda T. Pun et al.

Summary: This study investigated the prevalence of delirium and coma in critically ill patients with COVID-19, identifying benzodiazepine use and lack of family visitation as modifiable risk factors for delirium. These findings present an opportunity to reduce acute brain dysfunction in patients with COVID-19.

LANCET RESPIRATORY MEDICINE (2021)

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Article Anesthesiology

Barotrauma in mechanically ventilated patients with Coronavirus disease 2019: a survey of 38 hospitals in Lombardy, Italy

Alessandro Protti et al.

Summary: During the outbreak in Lombardy, Italy, the incidence of barotrauma in COVID-19 patients on invasive mechanical ventilation was 7.1%. Only a small number of cases occurred with ventilatory settings that may be considered non-protective.

MINERVA ANESTESIOLOGICA (2021)

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Article Critical Care Medicine

Role of total lung stress on the progression of early COVID-19 pneumonia

Silvia Coppola et al.

Summary: In early COVID-19 pneumonia, hypoxemia is not linked to computed tomography (CT) pathoanatomy, differently from typical ARDS. High lung stress was independently associated with the failure of non-invasive respiratory support.

INTENSIVE CARE MEDICINE (2021)

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Article Medicine, General & Internal