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Article
Biology
Andrea Torneri et al.
Summary: This study investigates the impact of different testing strategies on the dynamics of SARS-CoV-2 infection in a primary school environment. The study demonstrates that repetitive testing strategies can significantly reduce the attack rate in schools, but may result in more cases being detected and class and school closures.
Article
Multidisciplinary Sciences
Kaiyuan Sun et al.
Summary: The study reveals significant transmission heterogeneity of SARS-CoV-2, with a small proportion of individuals contributing to most secondary infections. Transmission risk is positively correlated with exposure duration and social interactions, modulated by demographic and clinical factors. During lockdown, transmission risk increases within families but decreases with isolation and quarantine measures for all types of contacts.
Article
Multidisciplinary Sciences
Jacob E. Lemieux et al.
Summary: Analysis of 772 complete genomes of SARS-CoV-2 from early in the Boston-area epidemic shows multiple introductions of the virus, with two distinct superspreading events. One at a nursing facility resulted in rapid transmission and significant mortality, while the other at an international business conference led to sustained community transmission and widespread spread. The genetic variation generated by these events differed substantially, indicating varying transmission dynamics in superspreading events.
Editorial Material
Multidisciplinary Sciences
Shamez N. Ladhani
Article
Medicine, General & Internal
Piero Poletti et al.
Summary: In this cohort study in Italy, more than half of close contacts of confirmed SARS-CoV-2 patients tested positive for the virus, but most of them did not develop respiratory symptoms or fever. The low proportion of children and young adults who developed symptoms highlights the challenges in identifying SARS-CoV-2 infections.
Article
Medicine, General & Internal
Christelle Meuris et al.
Summary: Recent data suggest a relatively low incidence of COVID-19 among children, but this prospective cohort study in a primary school found that the incidence of COVID-19 among children attending primary school was comparable to that observed among teachers and parents. Most transmission events were found to have originated from within the school, highlighting the need for additional measures to reduce transmission of SARS-CoV-2 in school settings.
Article
Public, Environmental & Occupational Health
Timothy Doyle et al.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2021)
Article
Biochemical Research Methods
Paul Tupper et al.
Summary: The study indicates that children and youth can acquire and transmit COVID-19 in school settings, leading to large transmission clusters and outbreaks. Using a mathematical model, the authors found that only frequent screening of the entire class can substantially reduce the size of infection clusters caused by variability in transmission rate.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Multidisciplinary Sciences
JO Lloyd-Smith et al.
