期刊
FITOTERAPIA
卷 161, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.fitote.2022.105244
关键词
Clinopodium polycephalum; Abietane diterpenoids; Triterpenoids; Anti-inflammatory activity
资金
- National Natural Science Foundation of China [81573694]
- Science Foundation of the Educational Department of Liaoning Province [LJKZ0920]
- Liaoning BaiQianWan Talents Program in 2018
Two previously undescribed diterpenes and one curious triterpenoid were isolated from Chnopodium polycephalum, a medicinal plant in China. Their structures were determined using various analytical techniques. These compounds showed inhibitory effects on NO production in cells without affecting cell viability.
Two previously undescribed diterpenes (1 and 2), as well as one curious triterpenoid were isolated from Chnopodium polycephalum, a medicinal plant distributed in southwestern and eastern China. Their structures were elucidated using MS analyses, UV spectrum, and extensive 2D-homo and hetemnuclear NMR data interpretations. Among them, 1 had an unusual skeletal characteristic produced by a rare methyl migration pathway. All monomer compounds exhibited inhibitory effects on NO production in LPS-induced RAW 264.7 cells without affecting cell viabilities, which were comparable to that of positive control.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据