Advances in the Pharmacological Activities and Effects of Perilla Ketone and Isoegomaketone

As components of a traditional Chinese herbal medicine with many physiological activities, perilla ketone and isoegomaketone isolated from perilla essential oil are important active components of Perilla frutescens. Recent studies have shown that these two compounds have promising antitumor, antifungal, antirheumatoid arthritis, antiobesity, anti-inflammatory, healing-promoting, and other activities and can be used to combat toxicity from immunotherapy. Therefore, the multitude of pharmacological activities and effects demonstrate the broad research potential of perilla ketone and isoegomaketone. However, no reviews have been published related to the pharmacological activities or effects of perilla ketone and isoegomaketone. The purpose of this review is as follows: (1) outline the recent advances made in understanding the pharmacological activities of perilla ketone and isoegomaketone; (2) summarize their effects; and (3) discuss future research perspectives.

Automated summary

Perilla ketone and isoegomaketone, important active components of Perilla frutescens, have been shown to exhibit various pharmacological activities such as antitumor, antifungal, anti-inflammatory effects, and potential in combating toxicity from immunotherapy. However, there is a lack of reviews on the pharmacological activities and effects of these compounds.