4.7 Article

Inhibition of human glioblastoma multiforme cells by 10,11-dehydrocur- vularin through the MMP-2 and PI3K/AKT signaling pathways

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation

Qun Zhao et al.

Summary: The study identified 10,11-dehydrocurvularin (DCV) as a selective inhibitor of STAT3 for intervention in breast cancer, demonstrating its ability to inhibit proliferation, migration, invasion, and induce apoptosis in breast cancer cell lines. DCV directly engages with STAT3 and inhibits its phosphorylation activity, leading to tumor growth inhibition without observed toxicity in mouse xenograft models.

ACTA PHARMACOLOGICA SINICA (2021)

Article Chemistry, Multidisciplinary

Intrinsic and Extrinsic Programming of Product Chain Length and Release Mode in Fungal Collaborating Iterative Polyketide Synthases

Chen Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Oncology

circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma

Jiansheng Chen et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Review Biochemistry & Molecular Biology

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

Miguel F. Sanmamed et al.

Review Acoustics

Current status and future perspectives of sonodynamic therapy in glioma treatment

Xiaobing Wang et al.

ULTRASONICS SONOCHEMISTRY (2017)

Article Oncology

The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines

Ismael Riquelme et al.

PATHOLOGY & ONCOLOGY RESEARCH (2016)

Review Chemistry, Medicinal

Benzenediol lactones: a class of fungal metabolites with diverse structural features and biological activities

Weiyun Shen et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Multidisciplinary Sciences

Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases

Yuquan Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Chemistry, Multidisciplinary

Thioesterase Domains of Fungal Nonreducing Polyketide Synthases Act as Decision Gates during Combinatorial Biosynthesis

Yuquan Xu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Multidisciplinary Sciences

Rational reprogramming of fungal polyketide first-ring cyclization

Yuquan Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis

Sandro Santagata et al.

ACS CHEMICAL BIOLOGY (2012)

Editorial Material Cell Biology

PI3K-PKB/Akt Pathway

Brian A. Hemmings et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Biochemistry & Molecular Biology

NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum

Amal H. Aly et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Review Clinical Neurology

Immunotherapy Approaches for Malignant Glioma From 2007 to 2009

Laura A. Johnson et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2010)

Review Oncology

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

Jeffrey A. Engelman

NATURE REVIEWS CANCER (2009)

Review Cell Biology

Malignant astrocytic glioma: genetics, biology, and paths to treatment

Frank B. Furnari et al.

GENES & DEVELOPMENT (2007)

Review Chemistry, Medicinal

Inhibitors of the HSP90 molecular chaperone: Attacking the master regulator in cancer

Edward McDonald et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)

Article Agriculture, Multidisciplinary

Bioactive metabolites from the fungus Nectria galligena, the main apple canker agent in Chile

M Gutiérrez et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)

Article Medicine, General & Internal

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

R Stupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Oncology

Factors influencing survival in high-grade gliomas

JC Buckner

SEMINARS IN ONCOLOGY (2003)