4.7 Article

Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Parasitology

MalDA, Accelerating Malaria Drug Discovery

Tuo Yang et al.

Summary: The Malaria Drug Accelerator (MalDA) is a consortium of 15 leading scientific laboratories aiming to improve and accelerate early antimalarial drug discovery by identifying new, essential, druggable targets. By sharing resources, the consortium strives to eliminate structural barriers often encountered in the drug discovery process.

TRENDS IN PARASITOLOGY (2021)

Article Microbiology

A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites

Henriette Bosson-Vanga et al.

Summary: This study presents a new chemical structure that is active against multiple stages of the human malaria parasite, including those resistant to artemisinins. The molecule also reduces transmission of the parasite to the mosquito vector in a mouse model. This new compound family shows promise for the development of novel antimalarial drugs with a unique multi-stage mechanism of action.

MICROBIOLOGY SPECTRUM (2021)

Article Immunology

Novel pfkelch13 Gene Polymorphism Associates With Artemisinin Resistance in Eastern India

Sabyasachi Das et al.

CLINICAL INFECTIOUS DISEASES (2019)

Article Medicine, General & Internal

Artemisinin Resistance in Plasmodium falciparum Malaria.

Arjen M. Dondorp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Chemistry, Multidisciplinary

Thiol ester-boronic acid coupling. A mechanistically unprecedented and general ketone synthesis

LS Liebeskind et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)

Article Chemistry, Organic

Preparation of 5-substituted 3-aminofuran-2-carboxylate esters

AM Redman et al.

ORGANIC LETTERS (2000)

Article Chemistry, Organic

A short, facile synthesis of 5-substituted 3-amino-1H-pyrrole-2-carboxylates

N Chen et al.

JOURNAL OF ORGANIC CHEMISTRY (2000)