4.5 Article

A novel nonsense variant in the CENPP gene segregates in a Swiss family with autosomal dominant low-frequency sensorineural hearing loss

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Summary: This study aimed to evaluate the potential value of endolymphatic hydrops (EH) in patients with unilateral idiopathic sudden sensorineural hearing loss (UISSNHL) through 3D-FLAIR MRI. EH was observed in UISSNHL patients and may be associated with the pathology of the low-frequency group, but not with prognosis. Assessing EH in other types of hearing loss might not be meaningful, as they may be more related to blood-labyrinth dysfunction.

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