相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug-Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach
Laura Maria Fuhr et al.
PHARMACEUTICS (2021)
Variability in fish bioconcentration factors: Influences of study design and consequences for regulation
Pim N. H. Wassenaar et al.
CHEMOSPHERE (2020)
Examining Uncertainty in In Vitro-In Vivo Extrapolation Applied in Fish Bioconcentration Models
Heike Laue et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2020)
ABC transporters in gills of rainbow trout (Oncorhynchus mykiss)
Christian Kropf et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2020)
In Vitro Biotransformation Assays Using Liver S9 Fractions and Hepatocytes from Rainbow Trout (Oncorhynchus mykiss): Overcoming Challenges with Difficult Test Fragrance Chemicals
Christian Kropf et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2020)
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
Manvendra Patel et al.
CHEMICAL REVIEWS (2019)
Biotransformation of Polycyclic Aromatic Hydrocarbons by Trout Liver S9 Fractions: Evaluation of Competitive Inhibition Using a Substrate Depletion Approach
John W. Nichols et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2019)
In vitro biotransformation of pharmaceuticals and pesticides by trout liver S9 in the presence and absence of carbamazepine
Junho Jeon et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019)
Estimating the Bioconcentration Factors of Hydrophobic Organic Compounds from Biotransformation Rates Using Rainbow Trout Hepatocytes
Jennifer J. Trowell et al.
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY (2018)
Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout: Results of an International Ring Trial
John Nichols et al.
TOXICOLOGICAL SCIENCES (2018)
PharmGKB summary: clozapine pathway, pharmacokinetics
Caroline F. Thorn et al.
PHARMACOGENETICS AND GENOMICS (2018)
ASSESSING THE BIOACCUMULATION POTENTIAL OF IONIZABLE ORGANIC COMPOUNDS: CURRENT KNOWLEDGE AND RESEARCH PRIORITIES
James M. Armitage et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2017)
Lysosomal adaptation: How cells respond to lysosomotropic compounds
Shuyan Lu et al.
PLOS ONE (2017)
Antiepileptic use for epilepsy and nonepilepsy disorders A population-based study (1998-2013)
Christine Leong et al.
NEUROLOGY (2016)
SLC transporters as therapeutic targets: emerging opportunities
Lawrence Lin et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
THE ORGANIC ANION TRANSPORTER (OAT) FAMILY: A SYSTEMS BIOLOGY PERSPECTIVE
Sanjay K. Nigam et al.
PHYSIOLOGICAL REVIEWS (2015)
Biotransformation in vitro: An essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data
Iwona Wilk-Zasadna et al.
TOXICOLOGY (2015)
IN VITRO BIOTRANSFORMATION RATES IN FISH LIVER S9: EFFECT OF DOSING TECHNIQUES
Yung-Shan Lee et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2014)
Influence of the CYP2D6 Isoenzyme in Patients Treated with Venlafaxine for Major Depressive Disorder: Clinical and Economic Consequences
Antoni Sicras-Mainar et al.
PLOS ONE (2014)
Utilization and Costs of Antipsychotic Agents: A Canadian Population-Based Study, 1996–2006
Silvia Alessi-Severini et al.
PSYCHIATRIC SERVICES (2014)
Enantiomer-Specific In Vitro Biotransformation of Select Pharmaceuticals in Rainbow Trout (Oncorhynchus mykiss)
Kristin A. Connors et al.
CHIRALITY (2013)
Toward improved models for predicting bioconcentration of well-metabolized compounds by rainbow trout using measured rates of in vitro intrinsic clearance
John W. Nichols et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2013)
Comparative pharmaceutical metabolism by rainbow trout (Oncorhynchus mykiss) liver S9 fractions
Kristin A. Connors et al.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2013)
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability
Fionn E. O'Brien et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment
Stefan Scholz et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2013)
Hepatic Clearance of 6 Polycyclic Aromatic Hydrocarbons by Isolated Perfused Trout Livers: Prediction From In Vitro Clearance by Liver S9 Fractions
John W. Nichols et al.
TOXICOLOGICAL SCIENCES (2013)
In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes
Emily M. Smith et al.
AQUATIC TOXICOLOGY (2012)
Lamotrigine is a substrate for OCT1 in brain endothelial cells
David Dickens et al.
BIOCHEMICAL PHARMACOLOGY (2012)
OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies
Megan Roth et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Constitutive mRNA expression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss)
Stephan Fischer et al.
AQUATIC TOXICOLOGY (2011)
The pH-dependent toxicity of basic pharmaceuticals in the green algae Scenedesmus vacuolatus can be explained with a toxicokinetic ion-trapping model
Judith Neuwoehner et al.
AQUATIC TOXICOLOGY (2011)
In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein
Chunbo Zhang et al.
EPILEPSIA (2011)
Optimization of an isolated perfused rainbow trout liver model: Clearance studies with 7-ethoxycoumarin
John W. Nichols et al.
AQUATIC TOXICOLOGY (2009)
Sertraline and its metabolite desmethylsertraline, but not bupropion or its three major metabolites, have high affinity for P-glycoprotein
Jun-Sheng Wang et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2008)
Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response: A pilot study
Georg Nikisch et al.
PHARMACOLOGICAL RESEARCH (2008)
Time-dependent CYP inhibition
Robert J. Riley et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)
A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic chemicals in aquatic organisms
Jon A. Arnot et al.
ENVIRONMENTAL REVIEWS (2006)
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
EM Leslie et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)
Internal exposure: Linking bioavailability to effects
BI Escher et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2004)
Inhibition of P-glycoprotein by newer antidepressants
J Weiss et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier:: evidence from microdialysis experiments in rats
H Potschka et al.
NEUROSCIENCE LETTERS (2002)
Carbamazepine is not a substrate for P-glycoprotein
A Owen et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2001)